@article{10.2337/dc08-1679,
    author = {Monami, Matteo and Vivarelli, Maria and Desideri, Carla Maria and Colombi, Claudia and Marchionni, Niccolò and Mannucci, Edoardo},
    title = "{Pulse Pressure and Prediction of Incident Foot Ulcers in Type 2 Diabetes}",
    journal = {Diabetes Care},
    volume = {32},
    number = {5},
    pages = {897-899},
    year = {2009},
    month = {02},
    abstract = "{To assess the relevance of pulse pressure as a predictor of foot ulcers in type 2 diabetic subjects.A cohort study was performed on a consecutive series of 1,945 type 2 diabetic outpatients without a foot ulcer at baseline. Incident foot ulcers were identified through the regional hospital discharge system, which contains ICD codes of current diagnoses.During a follow-up of mean ± SD 4.2 ± 2.2 years, 86 ulcers were observed. After adjusting for confounders, the highest quartiles of pulse pressure had a 2.39-fold (95\\% CI 1.14–5.02) risk of foot ulcers. When ischemic ulcers were considered separately, the highest pulse pressure quartile was associated with an increased age- and sex-adjusted risk (2.08 [95\\% CI 1.02–4.24]), whereas no increase of risk was observed for neuropathic ulcers.Elevated pulse pressure represents an independent predictor of foot ulcers in diabetic patients; this parameter should be considered for the stratification of risk of ischemic or neuroischemic ulcers.}",
    issn = {0149-5992},
    doi = {10.2337/dc08-1679},
    url = {https://doi.org/10.2337/dc08-1679},
    eprint = {https://diabetesjournals.org/care/article-pdf/32/5/897/602980/zdc00509000897.pdf},
}