Prediabetes: A Fundamental Text begins with an overview of the demographic, anthropometric, biobehavioral, and biochemical factors that drive the transition from normal blood glucose to prediabetes. Emerging knowledge from the fi elds of genomics, transcriptomics, microRNAs, metabolomics, and microbiomics is incorporated into a comprehensive treatise on the pathobiology of prediabetes.

The focus then shifts to evidence-based management of prediabetes and prevention of type 2 diabetes. Emphasis is placed on practical adaptations that would enable cost effective community diabetes prevention initiatives.

Interventions utilizing lifestyle modification are prioritized over medications, but novel approaches (including cyclical medication strategy, designer nutraceuticals, and metabolic surgery) are also discussed.

The deep understanding offered by Prediabetes: A Fundamental Text is critical to the discovery and delivery of programs for preventing diabetes, and is an essential resource for clinicians, researchers, public health practitioners, and policy makers.