To estimate the frequency of an early-morning glucose rise (EMR) in relatively unselected children with insulindependent diabetes mellitus (IDDM), we assessed capillary blood glucose (CBG) at midsleep (0200-0430) and prebreakfast (0700-0800) in 97 children with diabetes at camp. The EMR (prebreakfast CBG-midsleep CGB) was inversely related to the midsleep CBG level (r = −.45, P <.001). Of the 49 children with midsleep CBG <200 mg/dl, the mean EMR was 34 ± 60 mg/dl, and 18 of these children had rises of >40 mg/dl. In conclusion, when midsleep glycemia is <200 mg/dl, a rise in blood glucose from midsleep to prebreakfast, often >40 mg/dl, is a common element of glycemic control among children with IDDM. The relative importance of the Somogyi phenomenon, the dawn phenomenon, and mere insulin insufficiency in the early-morning hours cannot be determined from these data.
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Original Article|
July 01 1988
Frequency of Early-Morning Rise in Blood Glucose in Children With Diabetes at Camp
Bruce B Duncan, MD;
Bruce B Duncan, MD
Departments of Epidemiology and Biostatistics, University of North Carolina
Chapel Hill
Department of Medicine, Duke University
Durham, North Carolina
Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
Porto Alegre, Brazil
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Maria Ines Schmidt, MD, PhD;
Maria Ines Schmidt, MD, PhD
Departments of Epidemiology and Biostatistics, University of North Carolina
Chapel Hill
Department of Medicine, Duke University
Durham, North Carolina
Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
Porto Alegre, Brazil
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George J Ellis, III, MD;
George J Ellis, III, MD
Departments of Epidemiology and Biostatistics, University of North Carolina
Chapel Hill
Department of Medicine, Duke University
Durham, North Carolina
Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
Porto Alegre, Brazil
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Clarence E Davis, PhD;
Clarence E Davis, PhD
Departments of Epidemiology and Biostatistics, University of North Carolina
Chapel Hill
Department of Medicine, Duke University
Durham, North Carolina
Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
Porto Alegre, Brazil
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Gerardo Heiss, MD
Gerardo Heiss, MD
Departments of Epidemiology and Biostatistics, University of North Carolina
Chapel Hill
Department of Medicine, Duke University
Durham, North Carolina
Faculdade de Medicina, Universidade Federal do Rio Grande do Sul
Porto Alegre, Brazil
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Address correspondence and reprint requests to Bruce B. Duncan, MD, Assessoria Cientifica—Faculdade de Medicina, UFRGS, Rua Ramiro Barcellos, 2600/420, Porto Alegre, R. S. 90210, Brazil.
Citation
Bruce B Duncan, Maria Ines Schmidt, George J Ellis, Clarence E Davis, Gerardo Heiss; Frequency of Early-Morning Rise in Blood Glucose in Children With Diabetes at Camp. Diabetes Care 1 July 1988; 11 (7): 574–578. https://doi.org/10.2337/diacare.11.7.574
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