OBJECTIVE— To characterize demographic, therapeutic, and complication features of patients in the Fort Totten Diabetes Project and to assess the longitudinal impact of intervention strategies.

RESEARCH DESIGN AND METHODS— Individuals (n = 215) of varying American Indian ethnic origin and a quantum of mean age 53 yr (range 14–86 yr), 62% women, with type II diabetes of 9 yr average duration were studied. Annual chart audits of the complete diabetic population were conducted from 1984 to 1988.

RESULTS— Obesity is a major problem complicating diabetes management (average BMI 32 ± 0.9), but BMI does not correlate with glucose control as assessed by total GHb (r = 0.014, NS). Individuals lost an average of 3.7 kg (P < 0.001) during the audit years. Mean GHb declined for the population (11.3–9.7%, P < 0.025) during the interval, but no significant decline was evident when values for individuals were considered. Complication rates for retinopathy, nephropathy, and neuropathy paralleled those rates published for urban populations.

CONCLUSIONS— Diabetes mellitus in American Indians living in a rural, economically deprived area can be identified and cared for with success similar to that published for urban populations.

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