This report examines prospectively, in the Framingham cohort, the relation of diabetes and impaired glucose tolerance to each of the cardiovascular sequelae, taking into account age, sex, and associated cardiovascular risk factors. The incidence of cardiovascular disease, as well as the levels of cardiovascular risk factors, were found to be higher in diabetic than in nondiabetic men and women. The relative impact of diabetes on coronary heart disease, peripheral vascular disease, or stroke incidence was the same in men and women, but for cardiovascular mortality and cardiac failure the impact is greater for women. Present evidence suggests that alleviation of associated cardiovascular risk factors is the most promising course in reducing cardiovascular sequelae in diabetic patients.
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Proceedings of the Kroc Foundation International Conference on Epidemiology of Diabetes and its Macrovascular Complications| March 01 1979
Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham Study
Address reprint requests to W. B. Kannel, Framingham Study, 118 Lincoln Street, Framingham, Massachusetts 01701.
Diabetes Care 1979;2(2):120–126
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W B Kannel, D L McGee; Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham Study. Diabetes Care 1 March 1979; 2 (2): 120–126. https://doi.org/10.2337/diacare.2.2.120
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