A Novel Missense Mutation in the Homeodomain of the Hepatocyte Nuclear Factor-1 α/Maturity-Onset Diabetes of the Young 3 in a Japanese Early-Onset Type 2 Diabetic Patient and Time-Course of Glucose-Stimulated Insulin Secretion

Awata, Takuya; Kurihara, Susumu; Inoue, Kiyoaki; Inoue, Ikuo; Takei, Shin-Ichiro; Ishii, Chikara; Negishi, Kiyohiko; Namai, Kazuyuki; Kanazawa, Yasunori; Kuzuya, Takeshi; Katayama, Shigehiro

doi:10.2337/diacare.21.9.1569

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Letters: Observations| September 01 1998

A Novel Missense Mutation in the Homeodomain of the Hepatocyte Nuclear Factor-1 α/Maturity-Onset Diabetes of the Young 3 in a Japanese Early-Onset Type 2 Diabetic Patient and Time-Course of Glucose-Stimulated Insulin Secretion

Takuya Awata, MD;

Takuya Awata, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Susumu Kurihara, MD;

Susumu Kurihara, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Kiyoaki Inoue, MD;

Kiyoaki Inoue, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Ikuo Inoue, MD;

Ikuo Inoue, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Shin-Ichiro Takei, MD;

Shin-Ichiro Takei, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Chikara Ishii, MD;

Chikara Ishii, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Kiyohiko Negishi, MD;

Kiyohiko Negishi, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Kazuyuki Namai, MD;

Kazuyuki Namai, MD

Omiya Medical Center, Jichi Medical School

Saitama, Japan

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Yasunori Kanazawa, MD;

Yasunori Kanazawa, MD

Omiya Medical Center, Jichi Medical School

Saitama, Japan

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Takeshi Kuzuya, MD;

Takeshi Kuzuya, MD

Diabetes Center, JA Shioya General Hospital

Tochigi, Japan

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Shigehiro Katayama, MD

Fourth Department of Internal Medicine, Saitama Medical School

Saitama, Japan

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Address correspondence to Dr. Takuya Awata, Fourth Department of Internal Medicine, Saitama Medical School, 38 Morohongo, Moroyama, Irumagun, Saitama, 350-0495, Japan. E-mail: awata@saitama-med.ac.jp.

Diabetes Care 1998;21(9):1569–1571

https://doi.org/10.2337/diacare.21.9.1569

PubMed:

9727913

A Novel Missense Mutation in the Homeodomain of the Hepatocyte Nuclear Factor-1 α/Maturity-Onset Diabetes of the Young 3 in a Japanese Early-Onset Type 2 Diabetic Patient and Time-Course of Glucose-Stimulated Insulin Secretion

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A Novel Missense Mutation in the Homeodomain of the Hepatocyte Nuclear Factor-1 α/Maturity-Onset Diabetes of the Young 3 in a Japanese Early-Onset Type 2 Diabetic Patient and Time-Course of Glucose-Stimulated Insulin Secretion

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