Kahn and Davidson (1) conclude that inadequacies in the evidence base support inaction on diabetes prevention in the community. Because we lack evidence from randomized controlled trials of community-based translations of the Diabetes Prevention Program (DPP) showing long-term maintenance of weight loss and prevention of diabetes and diabetes complications, they state that “… it is premature to siphon off precious national health care resources or revenue going into health plans toward an intervention that has no clear clinical benefit” (1).

Fortunately, Kahn and Davidson are not responsible for developing public health policy. Many sound health policies are based on evidence that would fall short of their standard for action. Consider speed limits, seat belts, air bags, tobacco control, clean air, and water standards; none are based on randomized controlled trials required by Kahn and Davidson. The absence of ideal evidence does not remove the responsibility for acting in accordance with the best available evidence to set public health policy. In this situation, the best available evidence, though imperfect, supports the health benefits and return on investment in lifestyle behavior counseling to reduce weight and risk for diabetes in overweight and obese individuals at risk. Kahn and Davidson appear to be adhering to the admirable principles of evidence-based medicine; benefits of pharmacological or surgical interventions must be greater than the harms and worth the cost. However, unlike the introduction of a medication like metformin, lifestyle interventions to promote healthy eating and active living are unlikely to impose significant risk; hence, the cost-effectiveness and opportunity cost are the relevant considerations.

Kahn and Davidson omitted an economic analysis of the Healthy Living Partnerships to Prevent Diabetes (HELP PD) study (2). That analysis provided evidence that the DPP intervention can be delivered by lay community health workers in a group setting for approximately $850 per person over the first 2 years (2). This cost compared favorably with the first 2-year cost of DPP ($2,631). Furthermore, the HELP PD approach provided 2-year weight loss (4.2 kg) and glucose reduction (4.4 mg/dL) that compared well with DPP (3). Kahn and Davidson dismiss these results as artifact; alternatively, our translational approach worked because the program was embedded within a diabetes care center under direction of diabetes educators and used the DPP curriculum and trained community health workers in skillful group facilitation and provided DVDs to standardize intervention delivery.

Public health is best served when policy makers recognize that deciding not to act represents a policy decision and that while evidence evolves, waiting for perfect knowledge to support action would mean never acting to promote or protect the public health. Kahn and Davidson (1) see current evidence as insufficient to support action now. To the extent that policy makers disagree, it may reflect different standards of quality of evidence that different parties apply, along with different judgments regarding the cost of inaction. We agree completely that policy and environmental approaches are needed to address the root causes of the obesity and diabetes epidemics. In the interim, support of lifestyle programs targeting high-risk individuals will be needed to prevent diabetes.

Duality of Interest. No potential conflicts of interest relevant to this article were reported.

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