Issues

Topics: calorie restricted diet , diabetes mellitus, type 2 , diet , genetics , menarche

Diabetes Care October 2013, Vol.36, 3377-3378. doi:https://doi.org/10.2337/dc13-ti11

Commentary

The Challenging Chase for Nutrigenetic Predictors of Metabolic Responses to Dietary Interventions

Mark A. Sarzynski, PHD; Claude Bouchard, PHD

Abstracts

Topics: diet , genotype

Diabetes Care October 2013, Vol.36, 3379-3381. doi:https://doi.org/10.2337/dc13-1399

Original Research

Clinical Care / Education / Nutrition / Psychosocial Research

Disturbed Eating Behavior and Omission of Insulin in Adolescents Receiving Intensified Insulin Treatment: A nationwide population-based study

Line Wisting, MA; Dag Helge Frøisland, MD; Torild Skrivarhaug, MD; Knut Dahl-Jørgensen, MD; Øyvind Rø, MD

Abstract

Topics: adolescent , diabetes mellitus, type 1 , insulin , hemoglobin a, glycosylated , feeding behaviors

Diabetes Care October 2013, Vol.36, 3382-3387. doi:https://doi.org/10.2337/dc13-0431

Benchmarking Is Associated With Improved Quality of Care in Type 2 Diabetes: The OPTIMISE randomized, controlled trial

Michel P. Hermans, MD; Moses Elisaf, MD; Georges Michel, MD; Erik Muls, MD; Frank Nobels, MD; Hans Vandenberghe, MD; Carlos Brotons, MD; for the OPTIMISE (OPtimal Type 2 dIabetes Management Including benchmarking and Standard trEatment) International Steering Committee

Abstracts

Topics: benchmarking , diabetes mellitus, type 2 , follow-up , hemoglobin a, glycosylated , ldl cholesterol lipoproteins

Diabetes Care October 2013, Vol.36, 3388-3395. doi:https://doi.org/10.2337/dc12-1853

Empagliflozin as Add-on to Metformin Plus Sulfonylurea in Patients With Type 2 Diabetes: A 24-week, randomized, double-blind, placebo-controlled trial

Hans-Ulrich Häring, MD; Ludwig Merker, MD; Elke Seewaldt-Becker, PHD; Marc Weimer, PHD; Thomas Meinicke, MD; Hans J. Woerle, MD; Uli C. Broedl, MD; on behalf of the EMPA-REG METSU Trial Investigators

Abstracts

Topics: diabetes mellitus, type 2 , empagliflozin , hemoglobin a, glycosylated , metformin , sulfonylurea compounds

Diabetes Care October 2013, Vol.36, 3396-3404. doi:https://doi.org/10.2337/dc12-2673

NSE, a Potential Biomarker, Is Closely Connected to Diabetic Peripheral Neuropathy

Jianbo Li, MD; Hongman Zhang, MD; Min Xie, MD; Lingfei Yan, MD; Jiawei Chen, MD; Hongxing Wang, MD

Abstract

Topics: biological markers , diabetic neuropathies , neuropathy , peripheral neuropathy , diabetic autonomic neuropathy

Diabetes Care October 2013, Vol.36, 3405-3410. doi:https://doi.org/10.2337/dc13-0590

Clinical Inertia in People With Type 2 Diabetes: A retrospective cohort study of more than 80,000 people

Kamlesh Khunti, MD; Michael L. Wolden, MSC; Brian Larsen Thorsted, MSC; Marc Andersen, PHD; Melanie J. Davies, MD

Abstract

Topics: clinical inertia , diabetes mellitus, type 2 , follow-up , glycemic control , hemoglobin a, glycosylated

Diabetes Care October 2013, Vol.36, 3411-3417. doi:https://doi.org/10.2337/dc13-0331

Cellular and Humoral Immune Responses in Type 1 Diabetic Patients Participating in a Phase III GAD-alum Intervention Trial

Stina Axelsson, PHD; Mikael Chéramy, PHD; Linda Åkerman, MSC; Mikael Pihl, MSC; Johnny Ludvigsson, MD, PHD; Rosaura Casas, PHD

Abstracts

Topics: cytokine , generalized anxiety disorder , bodily secretions , immune response

Diabetes Care October 2013, Vol.36, 3418-3424. doi:https://doi.org/10.2337/dc12-2251

New-Onset Diabetes in Elderly Subjects: Association between HbA_1c levels, mortality, and coronary revascularization

Orit Twito, MD; Ella Ahron, MD; Anat Jaffe, MD; Shani Afek, MD; Efrat Cohen, MA; Martine Granek-Catarivas, MD; Pinchas Klein, MD; Doron Hermoni, MD

Abstract

Topics: coronary revascularization , hemoglobin a, glycosylated , older adult

Diabetes Care October 2013, Vol.36, 3425-3429. doi:https://doi.org/10.2337/dc12-2503

Safety and Efficacy of Sitagliptin Therapy for the Inpatient Management of General Medicine and Surgery Patients With Type 2 Diabetes: A pilot, randomized, controlled study

Guillermo E. Umpierrez, MD; Roma Gianchandani, MD; Dawn Smiley, MD; Sol Jacobs, MD; David H. Wesorick, MD; Christopher Newton, MD; Farnoosh Farrokhi, MD; Limin Peng, PHD; David Reyes, MD; Sangeeta Lathkar-Pradhan, MBBS; Francisco Pasquel, MD

Abstracts

Topics: diabetes mellitus, type 2 , glycemic control , insulin , insulin glargine , sitagliptin

Diabetes Care October 2013, Vol.36, 3430-3435. doi:https://doi.org/10.2337/dc13-0277

Needle-Free Jet Injection of Rapid-Acting Insulin Improves Early Postprandial Glucose Control in Patients With Diabetes

Elsemiek E.C. Engwerda, BSC; Cees J. Tack, MD; Bastiaan E. de Galan, MD

Abstracts

Topics: diabetes mellitus, type 2 , glucose , glycemic control , insulin , insulin administration

Diabetes Care October 2013, Vol.36, 3436-3441. doi:https://doi.org/10.2337/dc13-0492

IRS1 Genotype Modulates Metabolic Syndrome Reversion in Response to 2-Year Weight-Loss Diet Intervention: The POUNDS LOST trial

Qibin Qi, PHD; Min Xu, MD; Hongyu Wu, PHD; Liming Liang, PHD; Catherine M. Champagne, PHD; George A. Bray, MD; Frank M. Sacks, MD; Lu Qi, MD

Abstracts

Topics: diet , diet, high-fat , fat-restricted diet , genotype , metabolic syndrome x

Diabetes Care October 2013, Vol.36, 3442-3447. doi:https://doi.org/10.2337/dc13-0018

Effect of Moderate-Intensity Exercise Versus Activities of Daily Living on 24-Hour Blood Glucose Homeostasis in Male Patients With Type 2 Diabetes

Jan-Willem van Dijk, MSC; Maarten Venema, MSC; Willem van Mechelen, MD; Coen D.A. Stehouwer, MD; Fred Hartgens, MD; Luc J.C. van Loon, PHD

Abstracts

Topics: blood glucose , diabetes mellitus, type 2 , glucose , glycemic control , homeostasis

Diabetes Care October 2013, Vol.36, 3448-3453. doi:https://doi.org/10.2337/dc12-2620

Residual β-Cell Function 3–6 Years After Onset of Type 1 Diabetes Reduces Risk of Severe Hypoglycemia in Children and Adolescents

Jesper S. Sørensen, MD; Jesper Johannesen, MD; Flemming Pociot, MD; Kurt Kristensen, MD; Jane Thomsen, BN; N. Thomas Hertel, MD; Per Kjaersgaard, MD; Caroline Brorsson, MD; Niels H. Birkebaek, MD; the Danish Society for Diabetes in Childhood and Adolescence

Abstract

Topics: child , c-peptide , diabetes mellitus, type 1 , hemoglobin a, glycosylated , hypoglycemia

Diabetes Care October 2013, Vol.36, 3454-3459. doi:https://doi.org/10.2337/dc13-0418

Linagliptin Lowers Albuminuria on Top of Recommended Standard Treatment in Patients With Type 2 Diabetes and Renal Dysfunction

Per-Henrik Groop, MD; Mark E. Cooper, MBBS; Vlado Perkovic, MBBS; Angela Emser, PHD; Hans-Juergen Woerle, MD; Maximilian von Eynatten, MD

Abstract

Topics: albuminuria , diabetes mellitus, type 2 , linagliptin , urine albumin/creatinine ratio , kidney failure

Diabetes Care October 2013, Vol.36, 3460-3468. doi:https://doi.org/10.2337/dc13-0323

ST-Segment Elevation Myocardial Infarction in Women With Type 2 Diabetes

Edyta Radomska, MD; Marcin Sadowski, MD; Jacek Kurzawski, MD; Marek Gierlotka, MD; Lech Poloński, MD

Abstract

Topics: diabetes mellitus, type 2 , st segment elevation myocardial infarction , percutaneous coronary intervention

Diabetes Care October 2013, Vol.36, 3469-3475. doi:https://doi.org/10.2337/dc13-0394

Prandial Insulin Dosing Using the Carbohydrate Counting Technique in Hospitalized Patients With Type 2 Diabetes

Kathleen M. Dungan, MD; Colleen Sagrilla, BS; Mahmoud Abdel-Rasoul, MS; Kwame Osei, MD

Abstracts

Topics: carbohydrates , diabetes mellitus, type 2 , glucose , insulin , prandial insulin

Diabetes Care October 2013, Vol.36, 3476-3482. doi:https://doi.org/10.2337/dc13-0121

Minimal Functional β-Cell Mass in Intraportal Implants That Reduces Glycemic Variability in Type 1 Diabetic Recipients

Pieter Gillard, MD; Robert Hilbrands, MD; Ursule Van de Velde, MSCN; Zhidong Ling, MD; Da Hae Lee, MD; Ilse Weets, MD; Frans Gorus, MD; Christophe De Block, MD; Leonard Kaufman, PHD; Chantal Mathieu, MD; Daniel Pipeleers, MD; Bart Keymeulen, MD

Abstracts

Topics: c-peptide , implants , insulin , transplantation , fasting

Diabetes Care October 2013, Vol.36, 3483-3488. doi:https://doi.org/10.2337/dc13-0128

Diabetic Nephropathy and Microalbuminuria in Pregnant Women With Type 1 and Type 2 Diabetes: Prevalence, antihypertensive strategy, and pregnancy outcome

Julie Agner Damm, MD; Björg Ásbjörnsdóttir, MD; Nicoline Foged Callesen, BS; Jonathan M. Mathiesen, BS; Lene Ringholm, MD; Berit Woetmann Pedersen, MD; Elisabeth R. Mathiesen, MD

Abstract

Topics: antihypertensive agents , diabetes mellitus, type 1 , diabetes mellitus, type 2 , diabetic nephropathy , microalbuminuria

Diabetes Care October 2013, Vol.36, 3489-3494. doi:https://doi.org/10.2337/dc13-1031

Novel Soy Germ Pasta Enriched in Isoflavones Ameliorates Gastroparesis in Type 2 Diabetes: A pilot study

Kenneth D.R. Setchell, PHD; Elisabetta Nardi, MD; Pier-Maria Battezzati, MD; Stefania Asciutti, MD; Danilo Castellani, MD; Gabriele Perriello, MD; Carlo Clerici, MD

Abstracts

Topics: diabetes mellitus, type 2 , gastroparesis , isoflavones , gastric emptying

Diabetes Care October 2013, Vol.36, 3495-3497. doi:https://doi.org/10.2337/dc12-1615

Epidemiology / Health Services Research

Risk of a Recurrent Cardiovascular Event in Individuals With Type 2 Diabetes or Intermediate Hyperglycemia: The Hoorn Study

Amber A.W.A. van der Heijden, MSC; Esther van’t Riet, PHD; Sandra D.M. Bot, PHD; Suzanne C. Cannegieter, PHD; Coen D.A. Stehouwer, MD; Caroline A. Baan, PHD; Jacqueline M. Dekker, PHD; Giel Nijpels, MD

Abstract

Topics: cardiovascular event , diabetes mellitus, type 2 , hyperglycemia , follow-up , cardiovascular diseases

Diabetes Care October 2013, Vol.36, 3498-3502. doi:https://doi.org/10.2337/dc12-2691

Oxidative Stress and Response in Relation to Coronary Artery Disease in Type 1 Diabetes

Tina Costacou, PHD; Rhobert W. Evans, PHD; Gerald L. Schafer, MS; Trevor J. Orchard, MBBCH

Abstract

Topics: antioxidants , biological markers , coronary arteriosclerosis , diabetes mellitus, type 1 , follow-up

Diabetes Care October 2013, Vol.36, 3503-3509. doi:https://doi.org/10.2337/dc12-2378

Impact of Specific Glucose-Control Strategies on Microvascular and Macrovascular Outcomes in 58,000 Adults With Type 2 Diabetes

Romain Neugebauer, PHD; Bruce Fireman, MS; Jason A. Roy, PHD; Patrick J. O’Connor, MD

Abstract

Topics: albuminuria , diabetes mellitus, type 2 , follow-up , glucose , glycemic control

Diabetes Care October 2013, Vol.36, 3510-3516. doi:https://doi.org/10.2337/dc12-2675

Cancer Incidence Among Those Initiating Insulin Therapy With Glargine Versus Human NPH Insulin

Til Stürmer, MD; M. Alison Marquis, MSTAT; Haibo Zhou, PHD; James B. Meigs, MD; Soo Lim, MD; Lawrence Blonde, MD; Eileen MacDonald, MD; Ray Wang, MS; Lisa M. LaVange, PHD; Virginia Pate, MS; John B. Buse, MD

Abstract

Topics: cancer , insulin , insulin glargine , insulin human, isophane , breast cancer

Diabetes Care October 2013, Vol.36, 3517-3525. doi:https://doi.org/10.2337/dc13-0263

Age at Menarche and Type 2 Diabetes Risk: The EPIC-InterAct study

Cathy E. Elks, PHD; Ken K. Ong, FRCPCH; Robert A. Scott, PHD; Yvonne T. van der Schouw, PHD; Judith S. Brand, MSC; Petra A. Wark, MSC; Pilar Amiano, MSC; Beverley Balkau, PHD; Aurelio Barricarte, MD; Heiner Boeing, PHD; Ana Fonseca-Nunes, MSC; Paul W. Franks, PHD; Sara Grioni, BSC; Jytte Halkjaer, PHD; Rudolf Kaaks, PHD; Timothy J. Key, DPHIL; Kay Tee Khaw, MBBCHIR; Amalia Mattiello, MD; Peter M. Nilsson, MD; Kim Overvad, PHD; Domenico Palli, MD; J. Ramón Quirós, MD; Sabina Rinaldi, PHD; Olov Rolandsson, MD; Isabelle Romieu, PHD; Carlotta Sacerdote, MD; María-José Sánchez, MD; Annemieke M.W. Spijkerman, PHD; Anne Tjonneland, DRMEDSCI; Maria-Jose Tormo, MD; Rosario Tumino, MD; Daphne L. van der A, PHD; Nita G. Forouhi, PHD; Stephen J. Sharp, MSC; Claudia Langenberg, MD; Elio Riboli, MD; Nicholas J. Wareham, MD; The InterAct Consortium

Abstract

Topics: diabetes mellitus, type 2 , menarche , body mass index procedure , premature menarche , obesity

Diabetes Care October 2013, Vol.36, 3526-3534. doi:https://doi.org/10.2337/dc13-0446

HbA_1c and Risk of Severe Hypoglycemia in Type 2 Diabetes: The Diabetes and Aging Study

Kasia J. Lipska, MD; E. Margaret Warton, MPH; Elbert S. Huang, MD; Howard H. Moffet, MPH; Silvio E. Inzucchi, MD; Harlan M. Krumholz, MD; Andrew J. Karter, PHD

Abstract

Topics: hemoglobin a, glycosylated , hypoglycemia , diabetes mellitus, type 2 , glycemic control , glucose

Diabetes Care October 2013, Vol.36, 3535-3542. doi:https://doi.org/10.2337/dc13-0610

Disproportionate Body Composition and Neonatal Outcome in Offspring of Mothers With and Without Gestational Diabetes Mellitus

Martina Persson, MD; Helena Fadl, MD; Ulf Hanson, MD; Dharmintra Pasupathy, MD

Abstract

Topics: body composition , gestational diabetes , hypoglycemia , infant , macrosomia

Diabetes Care October 2013, Vol.36, 3543-3548. doi:https://doi.org/10.2337/dc13-0899

Risk of Metabolic Syndrome and Diabetes Among Young Twins and Singletons in Guinea-Bissau

Morten Bjerregaard-Andersen, MD; Lone Hansen, MLT; Leontina I. da Silva, BS; Luis C. Joaquím, MD; Ditte E. Hennild, BMSC; Lene Christiansen, DMSC; Peter Aaby, DMSC; Christine S. Benn, DMSC; Kaare Christensen, DMSC; Morten Sodemann, PHD; Dorte M. Jensen, PHD; Henning Beck-Nielsen, DMSC

Abstracts

Topics: hemoglobin a, glycosylated , twins , guinea-bissau , glucose

Diabetes Care October 2013, Vol.36, 3549-3556. doi:https://doi.org/10.2337/dc12-2653

Association Between Sleep Duration and Diabetes in Black and White Adults

Chandra L. Jackson, PHD; Susan Redline, MD; Ichiro Kawachi, MD; Frank B. Hu, MD

Abstract

Topics: sleep , sleep duration , health behavior , national health interview survey

Diabetes Care October 2013, Vol.36, 3557-3565. doi:https://doi.org/10.2337/dc13-0777

A Prediction Model for Adverse Outcome in Hospitalized Patients With Diabetes

Krishnarajah Nirantharakumar, MRCP; Karla Hemming, PHD; Parth Narendran, PHD; Tom Marshall, PHD; Jamie J. Coleman, MD

Abstracts

Topics: laboratory test finding , length of stay , prognostic factors , insulin , pathology, clinical

Diabetes Care October 2013, Vol.36, 3566-3572. doi:https://doi.org/10.2337/dc13-0452

Differences in the Management of Type 1 Diabetes Among Adults Under Excellent Control Compared With Those Under Poor Control in the T1D Exchange Clinic Registry

Jill H. Simmons, MD; Vincent Chen, PHD; Kellee M. Miller, MPH; Janet B. McGill, MD; Richard M. Bergenstal, MD; Robin S. Goland, MD; David M. Harlan, MD; Joseph F. Largay, PA; Elaine M. Massaro, MS; Roy W. Beck, MD; for the T1D Exchange Clinic Network

Abstracts

Topics: diabetes mellitus, type 1 , glycemic control , hemoglobin a, glycosylated , insulin , diabetic ketoacidosis

Diabetes Care October 2013, Vol.36, 3573-3577. doi:https://doi.org/10.2337/dc12-2643

Methylmercury Exposure and Incident Diabetes in U.S. Men and Women in Two Prospective Cohorts

Dariush Mozaffarian, MD; Peilin Shi, PHD; J. Steven Morris, PHD; Philippe Grandjean, MD; David S. Siscovick, MD; Donna Spiegelman, SCD; Frank B. Hu, MD

Abstract

Topics: mercury , methylmercury compounds , toenail , fish intake , omega-3 fatty acids

Diabetes Care October 2013, Vol.36, 3578-3584. doi:https://doi.org/10.2337/dc13-0894

Hypoglycemia Associated With Hospitalization and Adverse Events in Older People: Population-based cohort study

Sumit R. Majumdar, MD; Brenda R. Hemmelgarn, MD; Meng Lin, MSC; Kerry McBrien, MD; Braden J. Manns, MD; Marcello Tonelli, MD

Abstract

Topics: hypoglycemia

Diabetes Care October 2013, Vol.36, 3585-3590. doi:https://doi.org/10.2337/dc13-0523

HbA_1c and Lower-Extremity Amputation Risk in Low-Income Patients With Diabetes

Wenhui Zhao, MD; Peter T. Katzmarzyk, PHD; Ronald Horswell, PHD; Yujie Wang, MSC; Jolene Johnson, MD; Steven B. Heymsfield, MD; William T. Cefalu, MD; Donna H. Ryan, MD; Gang Hu, MD

Abstract

Topics: follow-up , hemoglobin a, glycosylated , lower extremity amputation

Diabetes Care October 2013, Vol.36, 3591-3598. doi:https://doi.org/10.2337/dc13-0437

Short Leg Length, a Marker of Early Childhood Deprivation, Is Associated With Metabolic Disorders Underlying Type 2 Diabetes: The PROMISE cohort study

Luke W. Johnston, BSC; Stewart B. Harris, MD; Ravi Retnakaran, MD; Hertzel C. Gerstein, MD; Bernard Zinman, MD; Jill Hamilton, MD; Anthony J. Hanley, PHD

Abstract

Topics: child , diabetes mellitus, type 2 , insulin sensitivity , leg , leg, short

Diabetes Care October 2013, Vol.36, 3599-3606. doi:https://doi.org/10.2337/dc13-0254

Emerging Technologies and Therapeutics

Prediction of Diabetes Based on Baseline Metabolic Characteristics in Individuals at High Risk

Ralph A. DeFronzo, MD; Devjit Tripathy, MD; Dawn C. Schwenke, PHD; MaryAnn Banerji, MD; George A. Bray, MD; Thomas A. Buchanan, MD; Stephen C. Clement, MD; Robert R. Henry, MD; Abbas E. Kitabchi, PHD; Sunder Mudaliar, MD; Robert E. Ratner, MD; Frankie B. Stentz, MS; Nicolas Musi, MD; Peter D. Reaven, MD; Amalia Gastaldelli, PHD; for the ACT NOW Study

Abstracts

Topics: diabetes mellitus, type 2 , follow-up , hemoglobin a, glycosylated , insulin , insulin resistance

Diabetes Care October 2013, Vol.36, 3607-3612. doi:https://doi.org/10.2337/dc13-0520

Use of an Insulin Bolus Advisor Improves Glycemic Control in Multiple Daily Insulin Injection (MDI) Therapy Patients With Suboptimal Glycemic Control: First results from the ABACUS trial

Ralph Ziegler, MD; David A. Cavan, MD; Iain Cranston, MD; Katharine Barnard, CPSYCHOL; Jacqueline Ryder, RGN; Claudia Vogel, DDB; Christopher G. Parkin, MS; Walter Koehler, MS; Iris Vesper, MS; Bettina Petersen, PHD; Matthias A. Schweitzer, MD; Robin S. Wagner, DVM

Abstracts

Topics: glycemic control , hypoglycemia , insulin , insulin administration , subcutaneous insulin delivery

Diabetes Care October 2013, Vol.36, 3613-3619. doi:https://doi.org/10.2337/dc13-0251

Pathophysiology / Complications

Renal Structure in Normoalbuminuric and Albuminuric Patients With Type 2 Diabetes and Impaired Renal Function

Elif I. Ekinci, PHD; George Jerums, MD; Alison Skene, MBBS; Paul Crammer, BAPPSC; David Power, PHD; Karey Y. Cheong, BSC; Sianna Panagiotopoulos, PHD; Karen McNeil, MBBS; Scott T. Baker, MBBS; Paola Fioretto, MD; Richard J. MacIsaac, PHD

Abstracts

Topics: diabetes mellitus, type 2 , kidney , kidney glomerulus , microalbuminuria , renal impairment

Diabetes Care October 2013, Vol.36, 3620-3626. doi:https://doi.org/10.2337/dc12-2572

Plasma Lipopolysaccharide Is Closely Associated With Glycemic Control and Abdominal Obesity: Evidence from bariatric surgery

Marius Trøseid, MD; Torunn K. Nestvold, MD; Knut Rudi, PHD; Hanne Thoresen, MD; Erik W. Nielsen, MD; Knut T. Lappegård, MD

Abstract

Topics: adipose tissue , bariatric surgery , cd14 antigen , glycemic control , hemoglobin a, glycosylated

Diabetes Care October 2013, Vol.36, 3627-3632. doi:https://doi.org/10.2337/dc13-0451

Albuminuria According to Status of Autoimmunity and Insulin Sensitivity Among Youth With Type 1 and Type 2 Diabetes

Amy K. Mottl, MD; Abigail Lauer, MS; Dana Dabelea, MD; David M. Maahs, MD; Ralph B. D’Agostino, Jr., PHD; Larry M. Dolan, MD; Lisa K. Gilliam, MD; Jean M. Lawrence, SCD; Beatriz Rodriguez, MD; Santica M. Marcovina, PHD; Giuseppina Imperatore, MD; Roopa Kanakatti Shankar, MBBS; Maryam Afkarian, MD; Kristi Reynolds, PHD; Angela D. Liese, PHD; Michael Mauer, MD; Elizabeth J. Mayer-Davis, PHD; for the SEARCH for Diabetes in Youth Study Group

Abstracts

Topics: adolescent , albuminuria , autoimmunity , diabetes mellitus, type 2 , insulin resistance

Diabetes Care October 2013, Vol.36, 3633-3638. doi:https://doi.org/10.2337/dc13-0568

Plasma Copeptin and Renal Outcomes in Patients With Type 2 Diabetes and Albuminuria

Gilberto Velho, MD; Nadine Bouby, PHD; Samy Hadjadj, MD; Nadia Matallah, MD; Kamel Mohammedi, MD; Frédéric Fumeron, PHD; Louis Potier, MD; Naïma Bellili-Munoz, PHD; Christopher Taveau, MSC; François Alhenc-Gelas, MD; Lise Bankir, PHD; Michel Marre, MD; Ronan Roussel, MD

Abstract

Topics: copeptin , follow-up , kidney , plasma , diabetes mellitus, type 2

Diabetes Care October 2013, Vol.36, 3639-3645. doi:https://doi.org/10.2337/dc13-0683

Corneal Nerve Loss Detected With Corneal Confocal Microscopy Is Symmetrical and Related to the Severity of Diabetic Polyneuropathy

Ioannis N. Petropoulos, MSC; Uazman Alam, MBCHB; Hassan Fadavi, MD; Omar Asghar, MBCHB; Patrick Green, MBCHB; Georgios Ponirakis, MPHIL; Andrew Marshall, MBCHB; Andrew J.M. Boulton, MBCHB; Mitra Tavakoli, MSC; Rayaz A. Malik, MBCHB

Abstract

Topics: cornea , nerve injuries , peripheral neuropathy , neuropathy , sensory perception

Diabetes Care October 2013, Vol.36, 3646-3651. doi:https://doi.org/10.2337/dc13-0193

Alterations to Bone Mineral Composition as an Early Indication of Osteomyelitis in the Diabetic Foot

Karen A. Esmonde-White, PHD; Francis W.L. Esmonde-White, PHD; Crystal M. Holmes, DPM; Michael D. Morris, PHD; Blake J. Roessler, MD

Abstract

Topics: amputation , diabetic foot ulcer , minerals , osteomyelitis , spectrum analysis, raman

Diabetes Care October 2013, Vol.36, 3652-3654. doi:https://doi.org/10.2337/dc13-0510

Long-Term Outcomes of Japanese Type 2 Diabetic Patients With Biopsy-Proven Diabetic Nephropathy

Miho Shimizu, MD; Kengo Furuichi, MD; Tadashi Toyama, MD; Shinji Kitajima, MD; Akinori Hara, MD; Kiyoki Kitagawa, MD; Yasunori Iwata, MD; Norihiko Sakai, MD; Toshinari Takamura, MD; Mitsuhiro Yoshimura, MD; Hitoshi Yokoyama, MD; Shuichi Kaneko, MD; Takashi Wada, MD; The Kanazawa Study Group for Renal Diseases and Hypertension

Abstract

Topics: albuminuria , biopsy , cardiovascular event , diabetic nephropathy , kidney

Diabetes Care October 2013, Vol.36, 3655-3662. doi:https://doi.org/10.2337/dc13-0298

Association of Subclinical Inflammation With Polyneuropathy in the Older Population: KORA F4 study

Christian Herder, PHD; Brenda W.C. Bongaerts, PHD; Wolfgang Rathmann, MD; Margit Heier, MD; Bernd Kowall, PHD; Wolfgang Koenig, MD; Barbara Thorand, PHD; Michael Roden, MD; Christa Meisinger, MD; Dan Ziegler, MD

Abstracts

Topics: immune mediator , inflammation , interleukin-6 , neuropathy , polyneuropathies

Diabetes Care October 2013, Vol.36, 3663-3670. doi:https://doi.org/10.2337/dc13-0382

The Role of Angiogenic and Antiangiogenic Factors in the Second Trimester in the Prediction of Preeclampsia in Pregnant Women With Type 1 Diabetes

Valerie A. Holmes, PHD; Ian S. Young, MD; Christopher C. Patterson, PHD; Michael J.A. Maresh, MD; Donald W.M. Pearson, MD; James D. Walker, MD; David R. McCance, MD; for the Diabetes and Preeclampsia Intervention Trial (DAPIT) Study Group

Abstract

Topics: angiogenesis , angiogenesis inhibitors , diabetes mellitus, type 1 , placenta growth factor , pre-eclampsia

Diabetes Care October 2013, Vol.36, 3671-3677. doi:https://doi.org/10.2337/dc13-0944

Early Diabetic Nephropathy: A complication of reduced insulin sensitivity in type 1 diabetes

Petter Bjornstad, MD; Janet K. Snell-Bergeon, PHD; Marian Rewers, MD; Diana Jalal, MD; Michel B. Chonchol, MD; Richard J. Johnson, MD; David M. Maahs, MD

Abstract

Topics: creatinine-based formula (ckd-epi) , cystatin c measurement , diabetes mellitus, type 1 , diabetic nephropathy , glomerular filtration rate

Diabetes Care October 2013, Vol.36, 3678-3683. doi:https://doi.org/10.2337/dc13-0631

Conduction Slowing in Diabetic Sensorimotor Polyneuropathy

Samantha K. Dunnigan, MSC; Hamid Ebadi, MD; Ari Breiner, MD; Hans D. Katzberg, MD; Leif E. Lovblom, MSC; Bruce A. Perkins, MD; Vera Bril, MD

Abstract

Topics: conduction velocity , demyelination , diabetes mellitus, type 1 , electrodiagnosis , nerve fibers

Diabetes Care October 2013, Vol.36, 3684-3690. doi:https://doi.org/10.2337/dc13-0746

Impact of Glucose Tolerance Status, Sex, and Body Size on Glucose Absorption Patterns During OGTTs

Kristine Færch, MSC; Giovanni Pacini, DSC; John J. Nolan, MD; Torben Hansen, MD; Andrea Tura, PHD; Dorte Vistisen, MSC

Abstract

Topics: glucose , oral glucose tolerance test , process of absorption

Diabetes Care October 2013, Vol.36, 3691-3697. doi:https://doi.org/10.2337/dc13-0592

Diabetic Autonomic Neuropathy Affects Symptom Generation and Brain-Gut Axis

Christina Brock, PHD; Eirik Søfteland, MD; Veronica Gunterberg, MD; Jens Brøndum Frøkjær, PHD; Dina Lelic, PHD; Birgitte Brock, PHD; Georg Dimcevski, PHD; Hans Gregersen, DMSC; Magnus Simrén, PHD; Asbjørn Mohr Drewes, PHD

Abstract

Topics: autonomic nervous system , brain , brain activity , diabetic autonomic neuropathy , electric stimulation

Diabetes Care October 2013, Vol.36, 3698-3705. doi:https://doi.org/10.2337/dc13-0347

SIRS Is Valid in Discriminating Between Severe and Moderate Diabetic Foot Infections

Dane K. Wukich, MD; Kimberlee B. Hobizal, DPM; Katherine Marie Raspovic, DPM; Bedda L. Rosario, PHD

Abstract

Topics: amputation , diabetic foot ulcer , infections , systemic inflammatory response syndrome

Diabetes Care October 2013, Vol.36, 3706-3711. doi:https://doi.org/10.2337/dc13-1083

Small- and Large-Fiber Neuropathy After 40 Years of Type 1 Diabetes: Associations with glycemic control and advanced protein glycation: the Oslo Study

Kari Anne Sveen, MD; Bassam Karimé, MD; Ellen Jørum, MD; Svein Ivar Mellgren, MD; Morten Wang Fagerland, PHD; Vincent M. Monnier, MD; Knut Dahl-Jørgensen, MD; Kristian F. Hanssen, MD

Abstract

Topics: diabetes mellitus, type 1 , glycation , glycemic control , hemoglobin a, glycosylated , neurons

Diabetes Care October 2013, Vol.36, 3712-3717. doi:https://doi.org/10.2337/dc13-0788

Obstructive Sleep Apnea and Diabetic Nephropathy: A cohort study

Abd A. Tahrani, PHD; Asad Ali, MRCP; Neil T. Raymond, MSC; Safia Begum; Kiran Dubb, MSC; Quratul-ain Altaf, MRCP; Milan K. Piya, MRCP; Anthony H. Barnett, MD; Martin J. Stevens, MD

Abstracts

Topics: 3-nitrotyrosine , albuminuria , apnea-hypopnea index procedure , continuous positive airway pressure , diabetes mellitus, type 2

Diabetes Care October 2013, Vol.36, 3718-3725. doi:https://doi.org/10.2337/dc13-0450

Endocrine Secretory Reserve and Proinsulin Processing in Recipients of Islet of Langerhans Versus Whole Pancreas Transplants

Nabeel M. Elkhafif, MD; Sophie Borot, MD; Philippe Morel, MD; Sandrine Demuylder-Mischler, RN; Laurianne Giovannoni, PHD; Christian Toso, MD; Domenico Bosco, PHD; Thierry Berney, MD

Abstract

Topics: insulin , proinsulin , c-peptide , pancreas transplantation , arginine

Diabetes Care October 2013, Vol.36, 3726-3731. doi:https://doi.org/10.2337/dc12-2710

Glycerol and Fatty Acids in Serum Predict the Development of Hyperglycemia and Type 2 Diabetes in Finnish Men

Yuvaraj Mahendran, MSC; Henna Cederberg, MD; Jagadish Vangipurapu, PHD; Antti J. Kangas, MSC (TECH); Pasi Soininen, PHD; Johanna Kuusisto, MD; Matti Uusitupa, MD; Mika Ala-Korpela, PHD; Markku Laakso, MD

Abstracts

Topics: cd95 antigens , diabetes mellitus, type 2 , fasting , fatty-acid synthase , fetal alcohol syndrome

Diabetes Care October 2013, Vol.36, 3732-3738. doi:https://doi.org/10.2337/dc13-0800

Cardiovascular and Metabolic Risk

Temporal Relationship Between Insulin Sensitivity and the Pubertal Decline in Physical Activity in Peripubertal Hispanic and African American Females

Donna Spruijt-Metz, PHD; Britni R. Belcher, PHD; Ya-Wen Hsu, PHD; Arianna D. McClain, PHD; Chih-Ping Chou, PHD; Selena Nguyen-Rodriguez, PHD; Marc J. Weigensberg, MD; Michael I. Goran, PHD

Abstracts

Topics: insulin , insulin sensitivity , lack of exercise , puberty , obesity

Diabetes Care October 2013, Vol.36, 3739-3745. doi:https://doi.org/10.2337/dc13-0083

Association of Hypoglycemic Treatment Regimens With Cardiovascular Outcomes in Overweight and Obese Subjects With Type 2 Diabetes: A substudy of the SCOUT trial

Adam Ali Ghotbi, MD; Lars Køber, MD; Nick Finer, MB; W. Philip T. James, MD; Arya M. Sharma, MD; Ian Caterson, MB; Walmir Coutinho, MD; Luc F. Van Gaal, MD; Christian Torp-Pedersen, MD; Charlotte Andersson, MD

Abstracts

Topics: cardiovascular system , diabetes mellitus, type 2 , diet , heart disease risk factors , hypoglycemic agents

Diabetes Care October 2013, Vol.36, 3746-3753. doi:https://doi.org/10.2337/dc13-0027

Subarachnoid Hemorrhage in Type 1 Diabetes: A prospective cohort study of 4,083 patients with diabetes

Miikka Korja, MD; Lena M. Thorn, MD; Stefanie Hägg, MB; Jukka Putaala, MD; Ron Liebkind, MD; Valma Harjutsalo, PHD; Carol M. Forsblom, PHD; Daniel Gordin, MD; Turgut Tatlisumak, MD; Per-Henrik Groop, MD; on behalf of the FinnDiane Study Group

Abstracts

Topics: diabetes mellitus, type 1 , subarachnoid hemorrhage , follow-up , obstructive sleep apnea , sleep apnea syndromes

Diabetes Care October 2013, Vol.36, 3754-3758. doi:https://doi.org/10.2337/dc13-0260

HbA_1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population: NIPPON DATA90

Masaru Sakurai, MD; Shigeyuki Saitoh, MD; Katsuyuki Miura, MD; Hideaki Nakagawa, MD; Hirofumi Ohnishi, MD; Hiroshi Akasaka, MD; Aya Kadota, MD; Yoshikuni Kita, PHD; Takehito Hayakawa, PHD; Takayoshi Ohkubo, MD; Akira Okayama, MD; Tomonori Okamura, MD; Hirotsugu Ueshima, MD; for the NIPPON DATA90 Research Group

Abstracts

Topics: cardiovascular diseases , hemoglobin a, glycosylated , coronary heart disease , cardiovascular death , ischemic stroke

Diabetes Care October 2013, Vol.36, 3759-3765. doi:https://doi.org/10.2337/dc12-2412

Matrix Gla Protein Species and Risk of Cardiovascular Events in Type 2 Diabetic Patients

Geertje W. Dalmeijer, PHD; Yvonne T. van der Schouw, PHD; Elke J. Magdeleyns, BSC; Cees Vermeer, PHD; W.M. Monique Verschuren, PHD; Jolanda M.A. Boer, PHD; Joline W.J. Beulens, PHD

Abstract

Topics: cardiovascular diseases , heart disease risk factors , heart failure , vitamin k , calcification

Diabetes Care October 2013, Vol.36, 3766-3771. doi:https://doi.org/10.2337/dc13-0065

Prognostic Impact of Aortic Stiffness in High-Risk Type 2 Diabetic Patients: The Rio de Janeiro Type 2 Diabetes Cohort Study

Claudia R.L. Cardoso, PHD; Marcel T. Ferreira, MD; Nathalie C. Leite, PHD; Gil F. Salles, PHD

Abstract

Topics: aortic stiffness , diabetes mellitus, type 2 , follow-up , pulse wave velocity , surrogate endpoints

Diabetes Care October 2013, Vol.36, 3772-3778. doi:https://doi.org/10.2337/dc13-0506

Hepatic Insulin Clearance Is Closely Related to Metabolic Syndrome Components

Olga Pivovarova, PHD; Wolfgang Bernigau, MSC; Thomas Bobbert, MD; Frank Isken, MD; Matthias Möhlig, MD; Joachim Spranger, MD; Martin O. Weickert, MD; Martin Osterhoff, PHD; Andreas F.H. Pfeiffer, MD; Natalia Rudovich, MD

Abstracts

Topics: c-peptide , drug clearance , insulin , metabolic syndrome x , oral glucose tolerance test

Diabetes Care October 2013, Vol.36, 3779-3785. doi:https://doi.org/10.2337/dc12-1203

Long-Lasting Improvements in Liver Fat and Metabolism Despite Body Weight Regain After Dietary Weight Loss

Sven Haufe, MSC; Verena Haas, MSC; Wolfgang Utz, MD; Andreas L. Birkenfeld, MD; Stephanie Jeran, MSC; Jana Böhnke; Anja Mähler, MSC; Friedrich C. Luft, MD; Jeanette Schulz-Menger, MD; Michael Boschmann, MD; Jens Jordan, MD; Stefan Engeli, MD

Abstracts

Topics: diet , follow-up , liver , weight reduction , abdomen

Diabetes Care October 2013, Vol.36, 3786-3792. doi:https://doi.org/10.2337/dc13-0102

Intima-Media Thickness in Severe Obesity: Links with BMI and metabolic status but not with systemic or adipose tissue inflammation

Elise Dalmas, PHD; Jean-François Kahn, MD; Philippe Giral, MD; Meriem Abdennour, PHD; Jean-Luc Bouillot, MD; Soraya Fellahi; Jean-Michel Oppert, MD; Karine Clément, MD; Michèle Guerre-Millo, PHD; Christine Poitou, MD

Abstracts

Topics: carotid intima-media thickness , inflammation , obesity , obesity, morbid , body mass index procedure

Diabetes Care October 2013, Vol.36, 3793-3802. doi:https://doi.org/10.2337/dc13-0256

Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence: A randomized controlled trial in a high-cardiovascular-risk population

Abstracts

Topics: cardiovascular event , cerebrovascular accident , diabetes mellitus, type 2 , diet , fasting blood glucose measurement

Diabetes Care October 2013, Vol.36, 3803-3811. doi:https://doi.org/10.2337/dc13-0955

Novel Communications in Diabetes

Prediction of Retinopathy at 20 Years After Onset in Younger-Onset Type 1 Diabetes Using Mean Metabolic Memory-Free HbA_1c Values: The importance of using HbA_1c data of total, not partial, diabetes duration

Akira Hirose, MD, PHD; Daisuke Furushima, PHN; Naohito Yamaguchi, MD, PHD; Shigehiko Kitano, MD, PHD; Yasuko Uchigata, MD, PHD

Abstract

Topics: diabetes mellitus, type 1 , hemoglobin a, glycosylated , retinal diseases , memory

Diabetes Care October 2013, Vol.36, 3812-3814. doi:https://doi.org/10.2337/dc13-0532

Increased Complement Activation in Human Type 1 Diabetes Pancreata

Patrick Rowe, PHD; Clive Wasserfall, MS; Byron Croker, MD, PHD; Martha Campbell-Thompson, DVM, PHD; Alberto Pugliese, PHD; Mark Atkinson, PHD; Desmond Schatz, MD

Abstracts

Topics: autoantibodies , complement activation , diabetes mellitus, type 1 , diabetes mellitus, type 2 , antigens

Diabetes Care October 2013, Vol.36, 3815-3817. doi:https://doi.org/10.2337/dc13-0203

Expression of Mesenchymal and α-Cell Phenotypic Markers in Islet β-Cells in Recently Diagnosed Diabetes

Michael G. White, MRES; Helen L. Marshall, PHD; Rebecca Rigby, BSC; Guo Cai Huang, PHD; Aimen Amer, FRCS; Trevor Booth, PHD; Steve White, FRCS; James A.M. Shaw, FRCP

Abstracts

Topics: anaplasia , glucagon , insulin , pancreas , phenotype

Diabetes Care October 2013, Vol.36, 3818-3820. doi:https://doi.org/10.2337/dc13-0705

Position Statement

Nutrition Therapy Recommendations for the Management of Adults With Diabetes

Alison B. Evert, MS, RD, CDE; Jackie L. Boucher, MS, RD, LD, CDE; Marjorie Cypress, PHD, C-ANP, CDE; Stephanie A. Dunbar, MPH, RD; Marion J. Franz, MS, RD, CDE; Elizabeth J. Mayer-Davis, PHD, RD; Joshua J. Neumiller, PHARMD, CDE, CGP, FASCP; Robin Nwankwo, MPH, RD, CDE; Cassandra L. Verdi, MPH, RD; Patti Urbanski, MED, RD, LD, CDE; William S. Yancy, Jr., MD, MHSC

Extract

Topics: carbohydrates , diabetes mellitus, type 2 , diet , eating , glycemic control

Diabetes Care October 2013, Vol.36, 3821-3842. doi:https://doi.org/10.2337/dc13-2042

Review Article

Barriers and Potential Solutions to Providing Optimal Guideline-Driven Care to Patients With Diabetes in the U.S.

Robert A. Vigersky, MD; Karen Fitzner, PHD; Jenifer Levinson, AB; for the Diabetes Working Group

Abstracts

Topics: guidelines , patient care management , standard of care , pediatrics , diabetes mellitus complications

Diabetes Care October 2013, Vol.36, 3843-3849. doi:https://doi.org/10.2337/dc13-0680

Erratum

Cluster-randomized trial of a mobile phone personalized behavioral intervention for blood glucose control. Diabetes Care 2011;34:1934–1942

CC Quinn; MD Shardell; ML Terrin; EA Barr; SH Ballew; AL Gruber-Baldini

Extract

Topics: behavioral health interventions , cell phones , glycemic control

Diabetes Care October 2013, Vol.36, 3850. doi:https://doi.org/10.2337/dc13-er11

Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care 2013;36:2981–2987

EM Moore; AG Mander; D Ames; MA Kotowicz; RP Carne; H Brodaty; M Woodward; K Boundy; KA Ellis; AI Bush; NG Faux; R Martins; C Szoeke; C Rowe; DA Watters; the AIBL Investigators

Extract

Topics: cognitive impairment , metformin

Diabetes Care October 2013, Vol.36, 3850. doi:https://doi.org/10.2337/dc13-er11b

Issues and Events

Extract

Topics: health personnel , ohio , oregon , insulin , insulin receptor

Diabetes Care October 2013, Vol.36, 3851. doi:https://doi.org/10.2337/dc13-ie11

Online Letters: Observations

Diagnosis of Gestational Diabetes Mellitus: A Different Paradigm to Consider

Nadia Manzoor, MD; Robert G. Moses, MD

Extract

Topics: gestational diabetes

Diabetes Care October 2013, Vol.36, e187. doi:https://doi.org/10.2337/dc13-1433

Sharing Insulin Pens: Are You Putting Patients at Risk?

Melissa K. Schaefer, MD; Rachel A. Kossover, MPH, RD; Joseph F. Perz, DRPH

Abstracts

Topics: insulin pens

Diabetes Care October 2013, Vol.36, e188-e189. doi:https://doi.org/10.2337/dc13-1522

Online Letters: Comments and Responses

Comment on: Wing et al. Effect of Intensive Lifestyle Intervention on Sexual Dysfunction in Women With Type 2 Diabetes: Results From an Ancillary Look AHEAD Study. Diabetes Care 2013;36:2937–2944

Maria Ida Maiorino, MD; Michela Petrizzo, MD; Giuseppe Bellastella, MD, PHD; Katherine Esposito, MD, PHD

Extract

Topics: diabetes mellitus, type 2 , female sexual dysfunction , life style , look ahead trial

Diabetes Care October 2013, Vol.36, e190. doi:https://doi.org/10.2337/dc13-1495

Response to Comment on: Wing et al. Effect of Intensive Lifestyle Intervention on Sexual Dysfunction in Women With Type 2 Diabetes: Results From an Ancillary Look AHEAD Study. Diabetes Care 2013;36:2937–2944

Rena R. Wing, PHD; Dale S. Bond, PHD; Isaias Noel Gendrano, III, MPH; Thomas Wadden, PHD; Judy Bahnson, BA, CCRP; Cora E. Lewis, MD; Stephen Schneider, MD; Abbas E. Kitabchi, PHD, MD; Brent Van Dorsten, PHD; Raymond C. Rosen, PHD; the Sexual Dysfunction Subgroup of the Look AHEAD Research Group

Extract

Topics: diabetes mellitus, type 2 , female sexual dysfunction , life style , look ahead trial

Diabetes Care October 2013, Vol.36, e191. doi:https://doi.org/10.2337/dc13-1699

Comment on: Raz et al. Personalized Management of Hyperglycemia in Type 2 Diabetes: Reflections From a Diabetes Care Editors’ Expert Forum. Diabetes Care 2013;36:1779–1788

Dario Giugliano, MD, PHD; Katherine Esposito, MD, PHD

Extract