Rachel A. Murphy; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Ilse Reinders; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Melissa E. Garcia; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Gudny Eiriksdottir; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Lenore J. Launer; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Rafn Benediktsson; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Vilmundur Gudnason; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Palmi V. Jonsson; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik); Tamara B. Harris; for the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik)

Abstract

View articletitled, Adipose Tissue, Muscle, and Function: Potential Mediators of Associations Between Body Weight and Mortality in Older Adults With Type 2 Diabetes

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Diabetes Care November 2014, Vol.37, 3213-3219. doi:https://doi.org/10.2337/dc14-0293

Collaborative Care Versus Screening and Follow-up for Patients With Diabetes and Depressive Symptoms: Results of a Primary Care–Based Comparative Effectiveness Trial

Jeffrey A. Johnson; Fatima Al Sayah; Lisa Wozniak; Sandra Rees; Allison Soprovich; Weiyu Qiu; Constance L. Chik; Pierre Chue; Peter Florence; Jennifer Jacquier; Pauline Lysak; Andrea Opgenorth; Wayne Katon; Sumit R. Majumdar

Abstracts

View articletitled, Collaborative Care Versus Screening and Follow-up for Patients With Diabetes and Depressive Symptoms: Results of a Primary Care–Based Comparative Effectiveness Trial

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Diabetes Care November 2014, Vol.37, 3220-3226. doi:https://doi.org/10.2337/dc14-1308

Emerging Technologies and Therapeutics

Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial

Anastassios G. Pittas; Bess Dawson-Hughes; Patricia R. Sheehan; Clifford J. Rosen; James H. Ware; William C. Knowler; Myrlene A. Staten; the D2d Research Group

Abstracts

View articletitled, Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial

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Diabetes Care November 2014, Vol.37, 3227-3234. doi:https://doi.org/10.2337/dc14-1005

New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Oral Agents and Basal Insulin: Glucose Control and Hypoglycemia in a 6-Month Randomized Controlled Trial (EDITION 2)

Hannele Yki-Järvinen; on behalf of the EDITION 2 Study Investigators; Richard Bergenstal; on behalf of the EDITION 2 Study Investigators; Monika Ziemen; on behalf of the EDITION 2 Study Investigators; Marek Wardecki; on behalf of the EDITION 2 Study Investigators; Isabel Muehlen-Bartmer; on behalf of the EDITION 2 Study Investigators; Emmanuelle Boelle; on behalf of the EDITION 2 Study Investigators; Matthew C. Riddle; on behalf of the EDITION 2 Study Investigators

Abstracts

View articletitled, New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Oral Agents and Basal Insulin: Glucose Control and Hypoglycemia in a 6-Month Randomized Controlled Trial (EDITION 2)

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Diabetes Care November 2014, Vol.37, 3235-3243. doi:https://doi.org/10.2337/dc14-0990

Pathophysiology / Complications

The Cross-sectional and Longitudinal Associations of Diabetic Retinopathy With Cognitive Function and Brain MRI Findings: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial

Christina E. Hugenschmidt; James F. Lovato; Walter T. Ambrosius; R. Nick Bryan; Hertzel C. Gerstein; Karen R. Horowitz; Lenore J. Launer; Ronald M. Lazar; Anne M. Murray; Emily Y. Chew; Ronald P. Danis; Jeff D. Williamson; Michael E. Miller; Jingzhong Ding

Abstracts

View articletitled, The Cross-sectional and Longitudinal Associations of Diabetic Retinopathy With Cognitive Function and Brain MRI Findings: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial

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Diabetes Care November 2014, Vol.37, 3244-3252. doi:https://doi.org/10.2337/dc14-0502

Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic Pain: A Randomized, Double-Blind, Placebo- and Active Comparator–Controlled, Adaptive Proof-of-Concept Phase 2 Study

Aaron Vinik; on behalf of the DS5565-A-U201 US Phase II Study Investigators; Julio Rosenstock; on behalf of the DS5565-A-U201 US Phase II Study Investigators; Uma Sharma; on behalf of the DS5565-A-U201 US Phase II Study Investigators; Karen Feins; on behalf of the DS5565-A-U201 US Phase II Study Investigators; Ching Hsu; on behalf of the DS5565-A-U201 US Phase II Study Investigators; Domenico Merante; on behalf of the DS5565-A-U201 US Phase II Study Investigators

Abstract

View articletitled, Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic Pain: A Randomized, Double-Blind, Placebo- and Active Comparator–Controlled, Adaptive Proof-of-Concept Phase 2 Study

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Diabetes Care November 2014, Vol.37, 3253-3261. doi:https://doi.org/10.2337/dc14-1044

Each Degree of Glucose Intolerance in Pregnancy Predicts Distinct Trajectories of β-Cell Function, Insulin Sensitivity, and Glycemia in the First 3 Years Postpartum

Caroline K. Kramer; Balakumar Swaminathan; Anthony J. Hanley; Philip W. Connelly; Mathew Sermer; Bernard Zinman; Ravi Retnakaran

Abstract

View articletitled, Each Degree of Glucose Intolerance in Pregnancy Predicts Distinct Trajectories of β-Cell Function, Insulin Sensitivity, and Glycemia in the First 3 Years Postpartum

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Diabetes Care November 2014, Vol.37, 3262-3269. doi:https://doi.org/10.2337/dc14-1529

Liraglutide and the Preservation of Pancreatic β-Cell Function in Early Type 2 Diabetes: The LIBRA Trial

Ravi Retnakaran; Caroline K. Kramer; Haysook Choi; Balakumar Swaminathan; Bernard Zinman

Abstracts

View articletitled, Liraglutide and the Preservation of Pancreatic β-Cell Function in Early Type 2 Diabetes: The LIBRA Trial

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Diabetes Care November 2014, Vol.37, 3270-3278. doi:https://doi.org/10.2337/dc14-0893

Effect of Hypoglycemia on Brain Structure in People With Type 2 Diabetes: Epidemiological Analysis of the ACCORD-MIND MRI Trial

Zi Zhang; James Lovato; Harsha Battapady; Christos Davatzikos; Hertzel C. Gerstein; Faramarz Ismail-Beigi; Lenore J. Launer; Anne Murray; Zubin Punthakee; Amilcar A. Tirado; Jeff Williamson; R. Nick Bryan; Michael E. Miller

Abstracts

View articletitled, Effect of Hypoglycemia on Brain Structure in People With Type 2 Diabetes: Epidemiological Analysis of the ACCORD-MIND MRI Trial

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Diabetes Care November 2014, Vol.37, 3279-3285. doi:https://doi.org/10.2337/dc14-0973

Impact of Islet Autoimmunity on the Progressive β-Cell Functional Decline in Type 2 Diabetes

Barbara M. Brooks-Worrell; Edward J. Boyko; Jerry P. Palmer

Abstract

View articletitled, Impact of Islet Autoimmunity on the Progressive β-Cell Functional Decline in Type 2 Diabetes

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Diabetes Care November 2014, Vol.37, 3286-3293. doi:https://doi.org/10.2337/dc14-0961

High Calorie Intake Is Associated With Worsening Insulin Resistance and β-Cell Function in Hispanic Women After Gestational Diabetes Mellitus

Zhanghua Chen; Richard M. Watanabe; Daniel O. Stram; Thomas A. Buchanan; Anny H. Xiang

Abstract

View articletitled, High Calorie Intake Is Associated With Worsening Insulin Resistance and β-Cell Function in Hispanic Women After Gestational Diabetes Mellitus

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Diabetes Care November 2014, Vol.37, 3294-3300. doi:https://doi.org/10.2337/dc14-1433

Cardiovascular and Metabolic Risk

Association Between Severe Hypoglycemia, Adverse Macrovascular Events, and Inflammation in the Edinburgh Type 2 Diabetes Study

Rachel Bedenis; Anna H. Price; Christine M. Robertson; Jo R. Morling; Brian M. Frier; Mark W.J. Strachan; Jackie F. Price

Abstract

View articletitled, Association Between Severe Hypoglycemia, Adverse Macrovascular Events, and Inflammation in the Edinburgh Type 2 Diabetes Study

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Diabetes Care November 2014, Vol.37, 3301-3308. doi:https://doi.org/10.2337/dc14-0908

Weight-Loss Therapy in Type 2 Diabetes: Effects of Phentermine and Topiramate Extended Release

W. Timothy Garvey; Donna H. Ryan; Nancy J.V. Bohannon; Robert F. Kushner; Miriam Rueger; Roman V. Dvorak; Barbara Troupin

Abstracts

View articletitled, Weight-Loss Therapy in Type 2 Diabetes: Effects of Phentermine and Topiramate Extended Release

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Diabetes Care November 2014, Vol.37, 3309-3316. doi:https://doi.org/10.2337/dc14-0930

Randomized Trial of Telephone Outreach to Improve Medication Adherence and Metabolic Control in Adults With Diabetes

Patrick J. O’Connor; Julie A. Schmittdiel; Ram D. Pathak; Ronald I. Harris; Katherine M. Newton; Kris A. Ohnsorg; Michele Heisler; Andrew T. Sterrett; Stanley Xu; Wendy T. Dyer; Marsha A. Raebel; Abraham Thomas; Emily B. Schroeder; Jay R. Desai; John F. Steiner

Abstracts

View articletitled, Randomized Trial of Telephone Outreach to Improve Medication Adherence and Metabolic Control in Adults With Diabetes

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Diabetes Care November 2014, Vol.37, 3317-3324. doi:https://doi.org/10.2337/dc14-0596

Changes in Adipose Tissue Depots and Metabolic Markers Following a 1-Year Diet and Exercise Intervention in Overweight and Obese Patients With Type 2 Diabetes

Dympna Gallagher; Stanley Heshka; David E. Kelley; John Thornton; Lawrence Boxt; F. Xavier Pi-Sunyer; Jennifer Patricio; Juliet Mancino; Jeanne M. Clark; the MRI Ancillary Study Group of the Look AHEAD Research Group

Abstracts

View articletitled, Changes in Adipose Tissue Depots and Metabolic Markers Following a 1-Year Diet and Exercise Intervention in Overweight and Obese Patients With Type 2 Diabetes

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Diabetes Care November 2014, Vol.37, 3325-3332. doi:https://doi.org/10.2337/dc14-1585

Novel Communications in Diabetes

Fetal Macrosomia and Neonatal Hyperinsulinemic Hypoglycemia Associated With Transplacental Transfer of Sulfonylurea in a Mother With KCNJ11-Related Neonatal Diabetes

Nele Myngheer; Karel Allegaert; Andrew Hattersley; Tim McDonald; Holger Kramer; Frances M. Ashcroft; Johan Verhaeghe; Chantal Mathieu; Kristina Casteels

Abstract

View articletitled, Fetal Macrosomia and Neonatal Hyperinsulinemic Hypoglycemia Associated With Transplacental Transfer of Sulfonylurea in a Mother With KCNJ11-Related Neonatal Diabetes

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Diabetes Care November 2014, Vol.37, 3333-3335. doi:https://doi.org/10.2337/dc14-1247

Review

The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions

Richard F. Hamman; for the SEARCH for Diabetes in Youth Study Group; Ronny A. Bell; for the SEARCH for Diabetes in Youth Study Group; Dana Dabelea; for the SEARCH for Diabetes in Youth Study Group; Ralph B. D’Agostino, Jr.; for the SEARCH for Diabetes in Youth Study Group; Lawrence Dolan; for the SEARCH for Diabetes in Youth Study Group; Giuseppina Imperatore; for the SEARCH for Diabetes in Youth Study Group; Jean M. Lawrence; for the SEARCH for Diabetes in Youth Study Group; Barbara Linder; for the SEARCH for Diabetes in Youth Study Group; Santica M. Marcovina; for the SEARCH for Diabetes in Youth Study Group; Elizabeth J. Mayer-Davis; for the SEARCH for Diabetes in Youth Study Group; Catherine Pihoker; for the SEARCH for Diabetes in Youth Study Group; Beatriz L. Rodriguez; for the SEARCH for Diabetes in Youth Study Group; Sharon Saydah; for the SEARCH for Diabetes in Youth Study Group

Abstracts

View articletitled, The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions

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Diabetes Care November 2014, Vol.37, 3336-3344. doi:https://doi.org/10.2337/dc14-0574