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1 November 2015
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In this Issue
In This Issue of Diabetes Care
Diabetes Care October 2015, Vol.38, 1995-1996. doi:https://doi.org/10.2337/dc15-ti11
Commentary
Diabetes and Obesity—Time Bombs to Be Defused
Diabetes Care October 2015, Vol.38, 1997-1999. doi:https://doi.org/10.2337/dci15-0008
Clinical Care / Education / Nutrition / Psychosocial Research
Insulin Dose and Cardiovascular Mortality in the ACCORD Trial
Elias S. Siraj; Daniel J. Rubin; Matthew C. Riddle; Michael E. Miller; Fang-Chi Hsu; Faramarz Ismail-Beigi; Shyh-Huei Chen; Walter T. Ambrosius; Abraham Thomas; William Bestermann; John B. Buse; Saul Genuth; Carol Joyce; Christopher S. Kovacs; Patrick J. O'Connor; Ronald J. Sigal; Sol Solomon; for the ACCORD Investigators
Diabetes Care October 2015, Vol.38, 2000-2008. doi:https://doi.org/10.2337/dc15-0598
Randomized, Double-Blind, Phase 3 Trial of Triple Therapy With Dapagliflozin Add-on to Saxagliptin Plus Metformin in Type 2 Diabetes
Chantal Mathieu; Aurelian Emil Ranetti; Danshi Li; Ella Ekholm; William Cook; Boaz Hirshberg; Hungta Chen; Lars Hansen; Nayyar Iqbal
Diabetes Care August 2015, Vol.38, 2009-2017. doi:https://doi.org/10.2337/dc15-0779
Randomized, Double-Blind Trial of Triple Therapy With Saxagliptin Add-on to Dapagliflozin Plus Metformin in Patients With Type 2 Diabetes
Stephan Matthaei; Doina Catrinoiu; Aleksander Celiński; Ella Ekholm; William Cook; Boaz Hirshberg; Hungta Chen; Nayyar Iqbal; Lars Hansen
Diabetes Care August 2015, Vol.38, 2018-2024. doi:https://doi.org/10.2337/dc15-0811
Momentary Predictors of Insulin Restriction Among Adults With Type 1 Diabetes and Eating Disorder Symptomatology
Rhonda M. Merwin; Natalia O. Dmitrieva; Lisa K. Honeycutt; Ashley A. Moskovich; James D. Lane; Nancy L. Zucker; Richard S. Surwit; Mark Feinglos; Jennifer Kuo
Diabetes Care September 2015, Vol.38, 2025-2032. doi:https://doi.org/10.2337/dc15-0753
Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations
Jacques Beltrand; Caroline Elie; Kanetee Busiah; Emmanuel Fournier; Nathalie Boddaert; Nadia Bahi-Buisson; Miriam Vera; Emmanuel Bui-Quoc; Isabelle Ingster-Moati; Marianne Berdugo; Albane Simon; Claire Gozalo; Zoubir Djerada; Isabelle Flechtner; Jean-Marc Treluyer; Raphael Scharfmann; Helene Cavé; Laurence Vaivre-Douret; Michel Polak; on behalf of the GlidKir Study Group
Diabetes Care October 2015, Vol.38, 2033-2041. doi:https://doi.org/10.2337/dc15-0837
Epidemiology / Health Services Research
Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study
Gina S. Wei; Sean A. Coady; Jared P. Reis; Mercedes R. Carnethon; Josef Coresh; Ralph B. D’Agostino, Sr.; David C. Goff, Jr.; David R. Jacobs, Jr.; Elizabeth Selvin; Caroline S. Fox
Diabetes Care September 2015, Vol.38, 2042-2049. doi:https://doi.org/10.2337/dc14-2770
Sleep Disturbances and Glucose Metabolism in Older Adults: The Cardiovascular Health Study
Linn Beate Strand; Mercedes Carnethon; Mary Lou Biggs; Luc Djoussé; Robert C. Kaplan; David S. Siscovick; John A. Robbins; Susan Redline; Sanjay R. Patel; Imre Janszky; Kenneth J. Mukamal
Diabetes Care September 2015, Vol.38, 2050-2058. doi:https://doi.org/10.2337/dc15-0137
Potential Impact of Prescribing Metformin According to eGFR Rather Than Serum Creatinine
Delphine S. Tuot; Feng Lin; Michael G. Shlipak; Vanessa Grubbs; Chi-yuan Hsu; Jerry Yee; Vahakn Shahinian; Rajiv Saran; Sharon Saydah; Desmond E. Williams; Neil R. Powe; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team; for the CDC CKD Surveillance Team
Diabetes Care August 2015, Vol.38, 2059-2067. doi:https://doi.org/10.2337/dc15-0542
Use of an α-Glucosidase Inhibitor and the Risk of Colorectal Cancer in Patients With Diabetes: A Nationwide, Population-Based Cohort Study
Diabetes Care August 2015, Vol.38, 2068-2074. doi:https://doi.org/10.2337/dc15-0563
Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project
Julian Esparza-Romero; Mauro E. Valencia; Rene Urquidez-Romero; Lisa S. Chaudhari; Robert L. Hanson; William C. Knowler; Eric Ravussin; Peter H. Bennett; Leslie O. Schulz
Diabetes Care August 2015, Vol.38, 2075-2082. doi:https://doi.org/10.2337/dc15-0089
The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients With Type 2 Diabetes
Diabetes Care September 2015, Vol.38, 2083-2089. doi:https://doi.org/10.2337/dc15-1358
Socioeconomic Disparities in Weight and Behavioral Outcomes Among American Indian and Alaska Native Participants of a Translational Lifestyle Intervention Project
Luohua Jiang; Haixiao Huang; Ann Johnson; Edward J. Dill; Janette Beals; Spero M. Manson; Yvette Roubideaux; the Special Diabetes Program for Indians Diabetes Prevention Demonstration Project
Diabetes Care October 2015, Vol.38, 2090-2099. doi:https://doi.org/10.2337/dc15-0394
Differential Association Between HDL Subclasses and the Development of Type 2 Diabetes in a Prospective Study of Japanese Americans
You-Cheol Hwang; Tomoshige Hayashi; Wilfred Y. Fujimoto; Steven E. Kahn; Donna L. Leonetti; Marguerite J. McNeely; Edward J. Boyko
Diabetes Care September 2015, Vol.38, 2100-2105. doi:https://doi.org/10.2337/dc15-0625
Emerging Technologies and Therapeutics
Safety and Efficacy of Omarigliptin (MK-3102), a Novel Once-Weekly DPP-4 Inhibitor for the Treatment of Patients With Type 2 Diabetes
Wayne H.-H. Sheu; Ira Gantz; Menghui Chen; Shailaja Suryawanshi; Arpana Mirza; Barry J. Goldstein; Keith D. Kaufman; Samuel S. Engel
Diabetes Care August 2015, Vol.38, 2106-2114. doi:https://doi.org/10.2337/dc15-0109
Effect of Repeated Glucagon Doses on Hepatic Glycogen in Type 1 Diabetes: Implications for a Bihormonal Closed-Loop System
Jessica R. Castle; Joseph El Youssef; Parkash A. Bakhtiani; Yu Cai; Jade M. Stobbe; Deborah Branigan; Katrina Ramsey; Peter Jacobs; Ravi Reddy; Mark Woods; W. Kenneth Ward
Diabetes Care September 2015, Vol.38, 2115-2119. doi:https://doi.org/10.2337/dc15-0754
Pathophysiology / Complications
Sickle Cell Trait Worsens Oxidative Stress, Abnormal Blood Rheology, and Vascular Dysfunction in Type 2 Diabetes
Mor Diaw; Vincent Pialoux; Cyril Martin; Abdoulaye Samb; Saliou Diop; Camille Faes; Pauline Mury; Niama Sall Diop; Saïd-Norou Diop; Brigitte Ranque; Maïmouna Ndour Mbaye; Nigel S. Key; Philippe Connes
Diabetes Care August 2015, Vol.38, 2120-2127. doi:https://doi.org/10.2337/dc15-0699
The Presence and Consequence of Nonalbuminuric Chronic Kidney Disease in Patients With Type 1 Diabetes
Lena M. Thorn; Daniel Gordin; Valma Harjutsalo; Stefanie Hägg; Robert Masar; Markku Saraheimo; Nina Tolonen; Johan Wadén; Per-Henrik Groop; Carol M. Forsblom; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group; on behalf of the FinnDiane Study Group
Diabetes Care August 2015, Vol.38, 2128-2133. doi:https://doi.org/10.2337/dc15-0641
Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial
Andrés Díaz-López; Nancy Babio; Miguel A. Martínez-González; Dolores Corella; Antonio J. Amor; Montse Fitó; Ramon Estruch; Fernando Arós; Enrique Gómez-Gracia; Miquel Fiol; José Lapetra; Lluís Serra-Majem; Josep Basora; F. Javier Basterra-Gortari; Vicente Zanon-Moreno; Miguel Ángel Muñoz; Jordi Salas-Salvadó; the PREDIMED Study Investigators
Diabetes Care September 2015, Vol.38, 2134-2141. doi:https://doi.org/10.2337/dc15-1117
Incidence of Fractures in Patients With Type 2 Diabetes in the SAVOR-TIMI 53 Trial
Ofri Mosenzon; Cheryl Wei; Jaime Davidson; Benjamin M. Scirica; Ilan Yanuv; Aliza Rozenberg; Boaz Hirshberg; Avivit Cahn; Christina Stahre; Krzysztof Strojek; Deepak L. Bhatt; Itamar Raz
Diabetes Care September 2015, Vol.38, 2142-2150. doi:https://doi.org/10.2337/dc15-1068
The Impact of Nocturnal Hypoglycemia on Sleep in Subjects With Type 2 Diabetes
Poul Jennum; Kirstine Stender-Petersen; Rasmus Rabøl; Niklas Rye Jørgensen; Pei-Ling Chu; Sten Madsbad
Diabetes Care September 2015, Vol.38, 2151-2157. doi:https://doi.org/10.2337/dc15-0907
Cardiovascular and Metabolic Risk
Subclinical Atherosclerosis Is Inversely Associated With Gray Matter Volume in African Americans With Type 2 Diabetes
Barry I. Freedman; Jasmin Divers; Christopher T. Whitlow; Donald W. Bowden; Nicholette D. Palmer; S. Carrie Smith; Jianzhao Xu; Thomas C. Register; J. Jeffrey Carr; Benjamin C. Wagner; Jeff D. Williamson; Kaycee M. Sink; Joseph A. Maldjian
Diabetes Care September 2015, Vol.38, 2158-2165. doi:https://doi.org/10.2337/dc15-1035
Novel Communications in Diabetes
Review
Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes
Diabetes Care October 2015, Vol.38, 2169-2176. doi:https://doi.org/10.2337/dc14-3082
Meta-analysis
Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis
Luca A. Lotta; Ali Abbasi; Stephen J. Sharp; Anna-Stina Sahlqvist; Dawn Waterworth; Julia M. Brosnan; Robert A. Scott; Claudia Langenberg; Nicholas J. Wareham
Diabetes Care October 2015, Vol.38, 2177-2187. doi:https://doi.org/10.2337/dc15-1218
Erratum
Erratum. Glycemic Variability Is Associated With Reduced Cardiac Autonomic Modulation in Women With Type 2 Diabetes. Diabetes Care 2015;38:682–688
Jesper Fleischer; Simon Lebech Cichosz; Pernille Hoeyem; Esben Laugesen; Per Loegstrup Poulsen; Jens Sandahl Christiansen; Lise Tarnow; Troels Krarup Hansen
Diabetes Care October 2015, Vol.38, 2188. doi:https://doi.org/10.2337/dc15-er11
Issues and Events
E-Letters: Observations
Enumerating β-Cells in Whole Human Islets: Sex Differences and Associations With Clinical Outcomes After Islet Transplantation
Enza Marchese; Caitlin Rodeghier; Rebecca S. Monson; Benjamin McCracken; Tingqi Shi; Wesley Schrock; Joan Martellotto; Jose Oberholzer; Kirstie K. Danielson
Diabetes Care September 2015, Vol.38, e176-e177. doi:https://doi.org/10.2337/dc15-0723
Association Between Plantar Temperatures and Triaxial Stresses in Individuals With Diabetes
Metin Yavuz; Ryan W. Brem; Alan G. Glaros; Alan Garrett; Michael Flyzik; Lawrence Lavery; Brian L. Davis; Henry Hilario; Linda S. Adams
Diabetes Care August 2015, Vol.38, e178-e179. doi:https://doi.org/10.2337/dc15-1147
Arterial Wall Elastic Properties and Endothelial Dysfunction in the Diabetic Foot Syndrome in Patients With Type 2 Diabetes
Alexios S. Antonopoulos; Gerasimos Siasos; Theodosia Konsola; Evangelos Oikonomou; Nicholas Tentolouris; Christina Kollia; Nikolaos Gouliopoulos; Theodoros Zografos; Athanasios G. Papavassiliou; Dimitris Tousoulis
Diabetes Care August 2015, Vol.38, e180-e181. doi:https://doi.org/10.2337/dc15-1042
Anti-PD1 Pembrolizumab Can Induce Exceptional Fulminant Type 1 Diabetes
Caroline Gaudy; Céline Clévy; Sandrine Monestier; Noémie Dubois; Yanis Préau; Stéphanie Mallet; Marie-Aleth Richard; Jean-Jacques Grob; René Valéro; Sophie Béliard
Diabetes Care August 2015, Vol.38, e182-e183. doi:https://doi.org/10.2337/dc15-1331
Peak Plantar Shear and Pressure and Foot Ulcer Locations: A Call to Revisit Ulceration Pathomechanics
Diabetes Care September 2015, Vol.38, e184-e185. doi:https://doi.org/10.2337/dc15-1596
Feasibility of Outpatient 24-Hour Closed-Loop Insulin Delivery
Martin I. de Bock; Anirban Roy; Matthew N. Cooper; Julie A. Dart; Carolyn L. Berthold; Adam J. Retterath; Kate E. Freeman; Benyamin Grosman; Natalie Kurtz; Fran Kaufman; Timothy W. Jones; Elizabeth A. Davis
Diabetes Care August 2015, Vol.38, e186-e187. doi:https://doi.org/10.2337/dc15-1047
E-Letters: Comments and Responses
Response to Comment on Krul-Poel et al. Effect of Vitamin D Supplementation on Glycemic Control in Patients With Type 2 Diabetes (SUNNY Trial): A Randomized Placebo-Controlled Trial. Diabetes Care 2015;38:1420–1426
Diabetes Care October 2015, Vol.38, e191-e192. doi:https://doi.org/10.2337/dci15-0005
Comment on Juraschek et al. Cardiorespiratory Fitness and Incident Diabetes: The FIT (Henry Ford ExercIse Testing) Project. Diabetes Care 2015;38:1075–1081
Diabetes Care October 2015, Vol.38, e193. doi:https://doi.org/10.2337/dc15-1427
Response to Comment on Juraschek et al. Cardiorespiratory Fitness and Incident Diabetes: The FIT (Henry Ford ExercIse Testing) Project. Diabetes Care 2015;38:1075–1081
Diabetes Care October 2015, Vol.38, e194-e195. doi:https://doi.org/10.2337/dci15-0007
Comment on Shukla et al. Food Order Has a Significant Impact on Postprandial Glucose and Insulin Levels. Diabetes Care 2015;38:e98–e99
Diabetes Care October 2015, Vol.38, e196. doi:https://doi.org/10.2337/dc15-1472
Response to Comment on Shukla et al. Food Order Has a Significant Impact on Postprandial Glucose and Insulin Levels. Diabetes Care 2015;38:e98–e99
Diabetes Care October 2015, Vol.38, e197. doi:https://doi.org/10.2337/dci15-0010
Comment on Erondu et al. Diabetic Ketoacidosis and Related Events in the Canagliflozin Type 2 Diabetes Clinical Program. Diabetes Care 2015;38:1680–1686
Diabetes Care October 2015, Vol.38, e198. doi:https://doi.org/10.2337/dc15-1700
