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1 June 2015
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care May 2015, Vol.38, 945-946. doi:https://doi.org/10.2337/dc15-ti06
Editor’s Note
Commentaries
Incretin-Based Drugs and Adverse Pancreatic Events: Almost a Decade Later and Uncertainty Remains
Diabetes Care May 2015, Vol.38, 951-953. doi:https://doi.org/10.2337/dc15-0347
Kelly West Award Lecture
Progressive Renal Decline: The New Paradigm of Diabetic Nephropathy in Type 1 Diabetes
Diabetes Care May 2015, Vol.38, 954-962. doi:https://doi.org/10.2337/dc15-0184
Profiles in Progress
James R. Gavin III, MD, PhD—A Humble and Remarkable Trailblazer, Scientist, Advocate, Mentor, and Educator for Diabetes
Diabetes Care May 2015, Vol.38, 963-967. doi:https://doi.org/10.2337/dc14-3035
Type 1 Diabetes at a Crossroads
Current State of Type 1 Diabetes Treatment in the U.S.: Updated Data From the T1D Exchange Clinic Registry
Kellee M. Miller; for the T1D Exchange Clinic Network; Nicole C. Foster; for the T1D Exchange Clinic Network; Roy W. Beck; for the T1D Exchange Clinic Network; Richard M. Bergenstal; for the T1D Exchange Clinic Network; Stephanie N. DuBose; for the T1D Exchange Clinic Network; Linda A. DiMeglio; for the T1D Exchange Clinic Network; David M. Maahs; for the T1D Exchange Clinic Network; William V. Tamborlane; for the T1D Exchange Clinic Network
Diabetes Care May 2015, Vol.38, 971-978. doi:https://doi.org/10.2337/dc15-0078
Current Concepts on the Pathogenesis of Type 1 Diabetes—Considerations for Attempts to Prevent and Reverse the Disease
Diabetes Care May 2015, Vol.38, 979-988. doi:https://doi.org/10.2337/dc15-0144
Prevention and Reversal of Type 1 Diabetes—Past Challenges and Future Opportunities
Diabetes Care May 2015, Vol.38, 997-1007. doi:https://doi.org/10.2337/dc15-0349
Impact of Fat, Protein, and Glycemic Index on Postprandial Glucose Control in Type 1 Diabetes: Implications for Intensive Diabetes Management in the Continuous Glucose Monitoring Era
Kirstine J. Bell; Carmel E. Smart; Garry M. Steil; Jennie C. Brand-Miller; Bruce King; Howard A. Wolpert
Diabetes Care May 2015, Vol.38, 1008-1015. doi:https://doi.org/10.2337/dc15-0100
Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia
Pratik Choudhary; Michael R. Rickels; Peter A. Senior; Marie-Christine Vantyghem; Paola Maffi; Thomas W. Kay; Bart Keymeulen; Nobuya Inagaki; Frantisek Saudek; Roger Lehmann; Bernhard J. Hering
Diabetes Care May 2015, Vol.38, 1016-1029. doi:https://doi.org/10.2337/dc15-0090
Islet Transplantation for Type 1 Diabetes, 2015: What Have We Learned From Alloislet and Autoislet Successes?
Diabetes Care May 2015, Vol.38, 1030-1035. doi:https://doi.org/10.2337/dc15-0079
Clinical Care / Education / Nutrition / Psychosocial Research
Selective Insulin Resistance in Homeostatic and Cognitive Control Brain Areas in Overweight and Obese Adults
Stephanie Kullmann; Martin Heni; Ralf Veit; Klaus Scheffler; Jürgen Machann; Hans-Ulrich Häring; Andreas Fritsche; Hubert Preissl
Diabetes Care March 2015, Vol.38, 1044-1050. doi:https://doi.org/10.2337/dc14-2319
Comparison of Glycemic and Metabolic Control in Youth With Type 1 Diabetes With and Without Antipsychotic Medication: Analysis From the Nationwide German/Austrian Diabetes Survey (DPV)
Angela Galler; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Esther Bollow; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Michael Meusers; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Bela Bartus; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Andrea Näke; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Holger Haberland; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Edith Schober; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus; Reinhard W. Holl; for the German Federal Ministry of Education and Research (BMBF) Competence Network Diabetes Mellitus
Diabetes Care March 2015, Vol.38, 1051-1057. doi:https://doi.org/10.2337/dc14-2538
Epidemiology / Health Services Research
The Hemoglobin Glycation Index Identifies Subpopulations With Harms or Benefits From Intensive Treatment in the ACCORD Trial
Diabetes Care April 2015, Vol.38, 1067-1074. doi:https://doi.org/10.2337/dc14-1844
Cardiorespiratory Fitness and Incident Diabetes: The FIT (Henry Ford ExercIse Testing) Project
Stephen P. Juraschek; Michael J. Blaha; Roger S. Blumenthal; Clinton Brawner; Waqas Qureshi; Steven J. Keteyian; John Schairer; Jonathan K. Ehrman; Mouaz H. Al-Mallah
Diabetes Care March 2015, Vol.38, 1075-1081. doi:https://doi.org/10.2337/dc14-2714
Relations Between Subclinical Disease Markers and Type 2 Diabetes, Metabolic Syndrome, and Incident Cardiovascular Disease: The Jackson Heart Study
Vanessa Xanthakis; Jung Hye Sung; Tandaw E. Samdarshi; Alethea N. Hill; Solomon K. Musani; Mario Sims; Kamel A. Ghraibeh; Philip R. Liebson; Herman A. Taylor; Ramachandran S. Vasan; Ervin R. Fox
Diabetes Care March 2015, Vol.38, 1082-1088. doi:https://doi.org/10.2337/dc14-2460
Incretin-Based Therapy and Risk of Acute Pancreatitis: A Nationwide Population-Based Case-Control Study
Reimar Wernich Thomsen; Lars Pedersen; Niels Møller; Johnny Kahlert; Henning Beck-Nielsen; Henrik Toft Sørensen
Diabetes Care January 2015, Vol.38, 1089-1098. doi:https://doi.org/10.2337/dc13-2983
Circulating and Dietary Trans Fatty Acids and Incident Type 2 Diabetes in Older Adults: The Cardiovascular Health Study
Qianyi Wang; Fumiaki Imamura; Wenjie Ma; Molin Wang; Rozenn N. Lemaitre; Irena B. King; Xiaoling Song; Mary L. Biggs; Joseph A. Delaney; Kenneth J. Mukamal; Luc Djousse; David S. Siscovick; Dariush Mozaffarian
Diabetes Care March 2015, Vol.38, 1099-1107. doi:https://doi.org/10.2337/dc14-2101
Pathophysiology / Complications
Effects of Acute Hypoglycemia on Working Memory and Language Processing in Adults With and Without Type 1 Diabetes
Kate V. Allen; Martin J. Pickering; Nicola N. Zammitt; Robert J. Hartsuiker; Matthew J. Traxler; Brian M. Frier; Ian J. Deary
Diabetes Care March 2015, Vol.38, 1108-1115. doi:https://doi.org/10.2337/dc14-1657
Diabetic Peripheral Neuropathy Compromises Balance During Daily Activities
Diabetes Care March 2015, Vol.38, 1116-1122. doi:https://doi.org/10.2337/dc14-1982
Hyperglycemia Potentiates the Slowing of Gastric Emptying Induced by Exogenous GLP-1
Mark P. Plummer; Karen L. Jones; Caroline E. Cousins; Laurence G. Trahair; Juris J. Meier; Marianne J. Chapman; Michael Horowitz; Adam M. Deane
Diabetes Care March 2015, Vol.38, 1123-1129. doi:https://doi.org/10.2337/dc14-3091
Kidney Injury Molecule-1 and the Loss of Kidney Function in Diabetic Nephropathy: A Likely Causal Link in Patients With Type 1 Diabetes
Nicolae M. Panduru; on behalf of the FinnDiane Study Group; Niina Sandholm; on behalf of the FinnDiane Study Group; Carol Forsblom; on behalf of the FinnDiane Study Group; Markku Saraheimo; on behalf of the FinnDiane Study Group; Emma H. Dahlström; on behalf of the FinnDiane Study Group; Lena M. Thorn; on behalf of the FinnDiane Study Group; Daniel Gordin; on behalf of the FinnDiane Study Group; Nina Tolonen; on behalf of the FinnDiane Study Group; Johan Wadén; on behalf of the FinnDiane Study Group; Valma Harjutsalo; on behalf of the FinnDiane Study Group; Angelika Bierhaus; on behalf of the FinnDiane Study Group; Per M. Humpert; on behalf of the FinnDiane Study Group; Per-Henrik Groop; on behalf of the FinnDiane Study Group
Diabetes Care March 2015, Vol.38, 1130-1137. doi:https://doi.org/10.2337/dc14-2330
Small Nerve Fiber Quantification in the Diagnosis of Diabetic Sensorimotor Polyneuropathy: Comparing Corneal Confocal Microscopy With Intraepidermal Nerve Fiber Density
Xin Chen; Jim Graham; Mohammad A. Dabbah; Ioannis N. Petropoulos; Georgios Ponirakis; Omar Asghar; Uazman Alam; Andrew Marshall; Hassan Fadavi; Maryam Ferdousi; Shazli Azmi; Mitra Tavakoli; Nathan Efron; Maria Jeziorska; Rayaz A. Malik
Diabetes Care March 2015, Vol.38, 1138-1144. doi:https://doi.org/10.2337/dc14-2422
Cardiovascular and Metabolic Risk
Efficacy and Safety of Saxagliptin in Older Participants in the SAVOR-TIMI 53 Trial
Lawrence A. Leiter; Hwee Teoh; Eugene Braunwald; Ofri Mosenzon; Avivit Cahn; K.M. Prasanna Kumar; Alena Smahelova; Boaz Hirshberg; Christina Stahre; Robert Frederich; Francois Bonnici; Benjamin M. Scirica; Deepak L. Bhatt; Itamar Raz; for the SAVOR-TIMI 53 Steering Committee and Investigators
Diabetes Care March 2015, Vol.38, 1145-1153. doi:https://doi.org/10.2337/dc14-2868
Changes in Gene Expression in Responders and Nonresponders to a Low-Intensity Walking Intervention
Megan E. Osler; Tomas Fritz; Kenneth Caidahl; Anna Krook; Juleen R. Zierath; Harriet Wallberg-Henriksson
Diabetes Care March 2015, Vol.38, 1154-1160. doi:https://doi.org/10.2337/dc14-2606
Review
Weight Management in Type 2 Diabetes: Current and Emerging Approaches to Treatment
Diabetes Care May 2015, Vol.38, 1161-1172. doi:https://doi.org/10.2337/dc14-1630
Errata
Erratum. Combination of Empagliflozin and Linagliptin as Second-Line Therapy in Subjects With Type 2 Diabetes Inadequately Controlled on Metformin. Diabetes Care 2015;38:384–393
Ralph A. DeFronzo; Andrew Lewin; Sanjay Patel; Dacheng Liu; Renee Kaste; Hans J. Woerle; Uli C. Broedl
Diabetes Care May 2015, Vol.38, 1173. doi:https://doi.org/10.2337/dc15-er06
Erratum. Initial Combination of Empagliflozin and Linagliptin in Subjects With Type 2 Diabetes. Diabetes Care 2015;38:394–402
Andrew Lewin; Ralph A. DeFronzo; Sanjay Patel; Dacheng Liu; Renee Kaste; Hans J. Woerle; Uli C. Broedl
Diabetes Care May 2015, Vol.38, 1173. doi:https://doi.org/10.2337/dc15-er06a
Issues and Events
E-Letters: Observations
Trends and Characteristics of Self-reported Case Presentation of Diabetes Diagnosis Among Youth From 2002 to 2010: Findings From the SEARCH for Diabetes in Youth Study
Sharon H. Saydah; Giuseppina Imperatore; Leora Henkin; Ralph D’Agostino, Jr.; Jasmin Divers; Elizabeth J. Mayer-Davis; Dana Dabelea; Georgeanna Klingensmith; Catherine Pihoker; Jean M. Lawrence
Diabetes Care May 2015, Vol.38, e84-e85. doi:https://doi.org/10.2337/dc15-0157
Role of Noninsulin Therapies Alone or in Combination in Chromosome 6q24-Related Transient Neonatal Diabetes: Sulfonylurea Improves but Does Not Always Normalize Insulin Secretion
David Carmody; Flavius A. Beca; Charles D. Bell; Jessica L. Hwang; Jazzmyne T. Dickens; Nancy A. Devine; Deborah J.G. Mackay; I. Karen Temple; Lisa R. Hays; Rochelle N. Naylor; Louis H. Philipson; Siri Atma W. Greeley
Diabetes Care May 2015, Vol.38, e86-e87. doi:https://doi.org/10.2337/dc14-3056
E-Letters: Comments and Responses
Comment on Hsu et al. BMI Cut Points to Identify At-Risk Asian Americans for Type 2 Diabetes Screening. Diabetes Care 2015;38:150–158
Diabetes Care May 2015, Vol.38, e90. doi:https://doi.org/10.2337/dc15-0470