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1 July 2016
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care June 2016, Vol.39, 1067-1068. doi:https://doi.org/10.2337/dc16-ti07
Editor’s Commentary
Diabetes Care: “Lagniappe” and “Seeing Is Believing”!
William T. Cefalu; Andrew J.M. Boulton; William V. Tamborlane; Robert G. Moses; Derek LeRoith; Eddie L. Greene; Frank B. Hu; George Bakris; Judith Wylie-Rosett; Julio Rosenstock; Katie Weinger; Lawrence Blonde; Mary de Groot; Stephen S. Rich; David D’Alessio; Matthew C. Riddle; Lyn Reynolds
Diabetes Care June 2016, Vol.39, 1069-1071. doi:https://doi.org/10.2337/dc16-0891
Commentaries
Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor
Diabetes Care June 2016, Vol.39, 1072-1074. doi:https://doi.org/10.2337/dci16-0008
Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists
Diabetes Care June 2016, Vol.39, 1075-1077. doi:https://doi.org/10.2337/dci15-0033
Diabetes Care Symposium
NIH Precision Medicine Initiative: Implications for Diabetes Research
Diabetes Care June 2016, Vol.39, 1080-1084. doi:https://doi.org/10.2337/dc16-0541
Precision Medicine in Diabetes: Is It Time?
Diabetes Care June 2016, Vol.39, 1085-1088. doi:https://doi.org/10.2337/dc16-0586
Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding: Results of the Longitudinal Assessment of Bariatric Surgery Study
Jonathan Q. Purnell; Faith Selzer; Abdus S. Wahed; John Pender; Walter Pories; Alfons Pomp; Greg Dakin; James Mitchell; Luis Garcia; Myrlene A. Staten; Carol McCloskey; David E. Cummings; David R. Flum; Anita Courcoulas; Bruce M. Wolfe
Diabetes Care June 2016, Vol.39, 1101-1107. doi:https://doi.org/10.2337/dc15-2138
CV Protection in the EMPA-REG OUTCOME Trial: A “Thrifty Substrate” Hypothesis
Diabetes Care June 2016, Vol.39, 1108-1114. doi:https://doi.org/10.2337/dc16-0330
Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis
Diabetes Care June 2016, Vol.39, 1115-1122. doi:https://doi.org/10.2337/dc16-0542
The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes
The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes
Diabetes Care April 2016, Vol.39, 1123-1126. doi:https://doi.org/10.2337/dc16-0824
Mitigating Meal-Related Glycemic Excursions in an Insulin-Sparing Manner During Closed-Loop Insulin Delivery: The Beneficial Effects of Adjunctive Pramlintide and Liraglutide
Jennifer L. Sherr; Neha S. Patel; Camille I. Michaud; Miladys M. Palau-Collazo; Michelle A. Van Name; William V. Tamborlane; Eda Cengiz; Lori R. Carria; Eileen M. Tichy; Stuart A. Weinzimer
Diabetes Care April 2016, Vol.39, 1127-1134. doi:https://doi.org/10.2337/dc16-0089
Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas
Jordan E. Pinsker; Joon Bok Lee; Eyal Dassau; Dale E. Seborg; Paige K. Bradley; Ravi Gondhalekar; Wendy C. Bevier; Lauren Huyett; Howard C. Zisser; Francis J. Doyle, III
Diabetes Care February 2016, Vol.39, 1135-1142. doi:https://doi.org/10.2337/dc15-2344
Multinational Home Use of Closed-Loop Control Is Safe and Effective
Stacey M. Anderson; Dan Raghinaru; Jordan E. Pinsker; Federico Boscari; Eric Renard; Bruce A. Buckingham; Revital Nimri; Francis J. Doyle, III; Sue A. Brown; Patrick Keith-Hynes; Marc D. Breton; Daniel Chernavvsky; Wendy C. Bevier; Paige K. Bradley; Daniela Bruttomesso; Simone Del Favero; Roberta Calore; Claudio Cobelli; Angelo Avogaro; Anne Farret; Jerome Place; Trang T. Ly; Satya Shanmugham; Moshe Phillip; Eyal Dassau; Isuru S. Dasanayake; Craig Kollman; John W. Lum; Roy W. Beck; Boris Kovatchev; for the Control to Range Study Group
Diabetes Care March 2016, Vol.39, 1143-1150. doi:https://doi.org/10.2337/dc15-2468
Day-and-Night Closed-Loop Glucose Control in Patients With Type 1 Diabetes Under Free-Living Conditions: Results of a Single-Arm 1-Month Experience Compared With a Previously Reported Feasibility Study of Evening and Night at Home
Eric Renard; Anne Farret; Jort Kropff; Daniela Bruttomesso; Mirko Messori; Jerome Place; Roberto Visentin; Roberta Calore; Chiara Toffanin; Federico Di Palma; Giordano Lanzola; Paolo Magni; Federico Boscari; Silvia Galasso; Angelo Avogaro; Patrick Keith-Hynes; Boris Kovatchev; Simone Del Favero; Claudio Cobelli; Lalo Magni; J. Hans DeVries; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium; for the AP@home Consortium
Diabetes Care April 2016, Vol.39, 1151-1160. doi:https://doi.org/10.2337/dc16-0008
Design Considerations for Artificial Pancreas Pivotal Studies
Diabetes Care December 2015, Vol.39, 1161-1167. doi:https://doi.org/10.2337/dc15-2449
Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial
Martin Tauschmann; Janet M. Allen; Malgorzata E. Wilinska; Hood Thabit; Zoë Stewart; Peiyao Cheng; Craig Kollman; Carlo L. Acerini; David B. Dunger; Roman Hovorka
Diabetes Care November 2015, Vol.39, 1168-1174. doi:https://doi.org/10.2337/dc15-2078
Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report
David M. Maahs; Bruce A. Buckingham; Jessica R. Castle; Ali Cinar; Edward R. Damiano; Eyal Dassau; J. Hans DeVries; Francis J. Doyle, III; Steven C. Griffen; Ahmad Haidar; Lutz Heinemann; Roman Hovorka; Timothy W. Jones; Craig Kollman; Boris Kovatchev; Brian L. Levy; Revital Nimri; David N. O’Neal; Moshe Philip; Eric Renard; Steven J. Russell; Stuart A. Weinzimer; Howard Zisser; John W. Lum
Diabetes Care March 2016, Vol.39, 1175-1179. doi:https://doi.org/10.2337/dc15-2716
Randomized Summer Camp Crossover Trial in 5- to 9-Year-Old Children: Outpatient Wearable Artificial Pancreas Is Feasible and Safe
Simone Del Favero; Federico Boscari; Mirko Messori; Ivana Rabbone; Riccardo Bonfanti; Alberto Sabbion; Dario Iafusco; Riccardo Schiaffini; Roberto Visentin; Roberta Calore; Yenny Leal Moncada; Silvia Galasso; Alfonso Galderisi; Valeria Vallone; Federico Di Palma; Eleonora Losiouk; Giordano Lanzola; Davide Tinti; Andrea Rigamonti; Marco Marigliano; Angela Zanfardino; Novella Rapini; Angelo Avogaro; Daniel Chernavvsky; Lalo Magni; Claudio Cobelli; Daniela Bruttomesso
Diabetes Care March 2016, Vol.39, 1180-1185. doi:https://doi.org/10.2337/dc15-2815
Diabetes Care Expert Forum
Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum
William T. Cefalu; John B. Buse; Jaakko Tuomilehto; G. Alexander Fleming; Ele Ferrannini; Hertzel C. Gerstein; Peter H. Bennett; Ambady Ramachandran; Itamar Raz; Julio Rosenstock; Steven E. Kahn
Diabetes Care June 2016, Vol.39, 1186-1201. doi:https://doi.org/10.2337/dc16-0873
Clinical Care / Education / Nutrition / Psychosocial Research
Cognitive Dysfunction: Part and Parcel of the Diabetic Foot
Rachel Natovich; Talma Kushnir; Ilana Harman-Boehm; Daniella Margalit; Itzhak Siev-Ner; Daniel Tsalichin; Ilia Volkov; Shmuel Giveon; Deborah Rubin-Asher; Tali Cukierman-Yaffe
Diabetes Care May 2016, Vol.39, 1202-1207. doi:https://doi.org/10.2337/dc15-2838
Epidemiology / Health Services Research
Seasonal Changes in the Prevalence of Gestational Diabetes Mellitus
Diabetes Care May 2016, Vol.39, 1218-1221. doi:https://doi.org/10.2337/dc16-0451
Disability-Free Life-Years Lost Among Adults Aged ≥50 Years With and Without Diabetes
Barbara H. Bardenheier; Ji Lin; Xiaohui Zhuo; Mohammed K. Ali; Theodore J. Thompson; Yiling J. Cheng; Edward W. Gregg
Diabetes Care December 2015, Vol.39, 1222-1229. doi:https://doi.org/10.2337/dc15-1095
Emerging Technologies and Therapeutics
Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia
Bernhard J. Hering; William R. Clarke; Nancy D. Bridges; Thomas L. Eggerman; Rodolfo Alejandro; Melena D. Bellin; Kathryn Chaloner; Christine W. Czarniecki; Julia S. Goldstein; Lawrence G. Hunsicker; Dixon B. Kaufman; Olle Korsgren; Christian P. Larsen; Xunrong Luo; James F. Markmann; Ali Naji; Jose Oberholzer; Andrew M. Posselt; Michael R. Rickels; Camillo Ricordi; Mark A. Robien; Peter A. Senior; A.M. James Shapiro; Peter G. Stock; Nicole A. Turgeon; for the Clinical Islet Transplantation Consortium
Diabetes Care April 2016, Vol.39, 1230-1240. doi:https://doi.org/10.2337/dc15-1988
Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies
Christof M. Kazda; Ying Ding; Ronan P. Kelly; Parag Garhyan; Chunxue Shi; Chay Ngee Lim; Haoda Fu; David E. Watson; Andrew J. Lewin; William H. Landschulz; Mark A. Deeg; David E. Moller; Thomas A. Hardy
Diabetes Care December 2015, Vol.39, 1241-1249. doi:https://doi.org/10.2337/dc15-1643
Pathophysiology / Complications
Maternal Serum Prolactin and Prediction of Postpartum β-Cell Function and Risk of Prediabetes/Diabetes
Ravi Retnakaran; Chang Ye; Caroline K. Kramer; Philip W. Connelly; Anthony J. Hanley; Mathew Sermer; Bernard Zinman
Diabetes Care April 2016, Vol.39, 1250-1258. doi:https://doi.org/10.2337/dc16-0043
Cardiovascular and Metabolic Risk
Dynamic Changes in Renal Function Are Associated With Major Cardiovascular Events in Patients With Type 2 Diabetes
Stéphanie Ragot; Pierre-Jean Saulnier; Gilberto Velho; Elise Gand; Astrid de Hauteclocque; Yousri Slaoui; Louis Potier; Philippe Sosner; Jean-Michel Halimi; Philippe Zaoui; Vincent Rigalleau; Frederic Fumeron; Ronan Roussel; Michel Marre; Samy Hadjadj; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups; on behalf of the SURDIAGENE and DIABHYCAR study groups
Diabetes Care May 2016, Vol.39, 1259-1266. doi:https://doi.org/10.2337/dc15-2607
Cardiovascular Mortality in Patients With Type 2 Diabetes and Recent Acute Coronary Syndromes From the EXAMINE Trial
William B. White; Stuart Kupfer; Faiez Zannad; Cyrus R. Mehta; Craig A. Wilson; Lanyu Lei; George L. Bakris; Steven E. Nissen; William C. Cushman; Simon R. Heller; Richard M. Bergenstal; Penny R. Fleck; Christopher P. Cannon; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators; for the EXAMINE Investigators
Diabetes Care June 2016, Vol.39, 1267-1273. doi:https://doi.org/10.2337/dc16-0303
Meta-analysis
Prognostic Value of Coronary Computed Tomography Angiography in Patients With Diabetes: A Meta-analysis
Csilla Celeng; Pál Maurovich-Horvat; Brian B. Ghoshhajra; Béla Merkely; Tim Leiner; Richard A.P. Takx
Diabetes Care June 2016, Vol.39, 1274-1280. doi:https://doi.org/10.2337/dc16-0281
Point-Counterpoint
Should Restrictions Be Relaxed for Metformin Use in Chronic Kidney Disease? No, We Should Never Again Compromise Safety!
Diabetes Care June 2016, Vol.39, 1281-1286. doi:https://doi.org/10.2337/dc15-2327
Should Restrictions Be Relaxed for Metformin Use in Chronic Kidney Disease? Yes, They Should Be Relaxed! What’s the Fuss?
Diabetes Care June 2016, Vol.39, 1287-1291. doi:https://doi.org/10.2337/dc15-2534
Clinical Images in Diabetes
Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets
Diabetes Care June 2016, Vol.39, 1292-1294. doi:https://doi.org/10.2337/dc16-0737
Issues and Events
E-Letters: Comments and Responses
Comment on Mita et al. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial. Diabetes Care 2016;39:455–464
Diabetes Care June 2016, Vol.39, e102-e103. doi:https://doi.org/10.2337/dc16-0475
Response to Comment on Mita et al. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial. Diabetes Care 2016;39:455–464
Diabetes Care June 2016, Vol.39, e104-e105. doi:https://doi.org/10.2337/dci16-0012
E-Letters: Observations
IADPSG and WHO 2013 Gestational Diabetes Mellitus Criteria Identify Obese Women With Marked Insulin Resistance in Early Pregnancy
Jürgen Harreiter; David Simmons; Gernot Desoye; Rosa Corcoy; Juan M. Adelantado; Roland Devlieger; Andre van Assche; Sander Galjaard; Peter Damm; Elisabeth R. Mathiesen; Dorte M. Jensen; Lise Lotte T. Andersen; Fidelma Dunne; Annunziata Lapolla; Maria G. Dalfra; Alessandra Bertolotto; Urzula Mantaj; Ewa Wender-Ozegowska; Agnieszka Zawiejska; David Hill; Judith G.M. Jelsma; Frank J. Snoek; Christof Worda; Dagmar Bancher-Todesca; Mireille N.M. van Poppel; Alexandra Kautzky-Willer; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group; on behalf of the DALI Core Investigator group
Diabetes Care May 2016, Vol.39, e90-e92. doi:https://doi.org/10.2337/dc16-0200
HbA1c-Based Classification Reveals Epidemic of Diabetes and Prediabetes in Vietnam
Diabetes Care May 2016, Vol.39, e93-e94. doi:https://doi.org/10.2337/dc16-0654
Nocturnal Hypoglycemia and Physical Activity in Children With Diabetes: New Insights by Continuous Glucose Monitoring and Accelerometry
Diabetes Care May 2016, Vol.39, e95-e96. doi:https://doi.org/10.2337/dc16-0411
Exhaled Breath Isoprene Rises During Hypoglycemia in Type 1 Diabetes
Sankalpa Neupane; Robert Peverall; Graham Richmond; Tom P.J. Blaikie; David Taylor; Gus Hancock; Mark L. Evans
Diabetes Care June 2016, Vol.39, e97-e98. doi:https://doi.org/10.2337/dc16-0461
Evaluating the Quality of Comprehensive Cardiometabolic Care for Patients With Type 2 Diabetes in the U.S.: The Diabetes Collaborative Registry
Suzanne V. Arnold; Silvio E. Inzucchi; Darren K. McGuire; Sanjeev N. Mehta; Abhinav Goyal; Laurence S. Sperling; Thomas M. Maddox; Daniel Einhorn; Nathan D. Wong; Robert E. Ratner; Niklas Hammar; Peter Fenici; John J. Sheehan; Jennifer L. Wong; Mikhail Kosiborod
Diabetes Care May 2016, Vol.39, e99-e101. doi:https://doi.org/10.2337/dc16-0585
