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August 2016
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care July 2016, Vol.39, 1297-1298. doi:https://doi.org/10.2337/dc16-ti08
Perspectives in Care
Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions
Diabetes Care July 2016, Vol.39, 1299-1306. doi:https://doi.org/10.2337/dc15-2727
Commentaries
Evaluation of a Technology to Support a Translational Diabetes Prevention Intervention
Diabetes Care July 2016, Vol.39, 1307-1308. doi:https://doi.org/10.2337/dci16-0001
Clinical Care / Education / Nutrition / Psychosocial Research
Neuronal Food Reward Activity in Patients With Type 2 Diabetes With Improved Glycemic Control After Bariatric Surgery
Sabine Frank; Jaana M. Heinze; Andreas Fritsche; Katarzyna Linder; Maximilian von Feilitzsch; Alfred Königsrainer; Hans-Ulrich Häring; Ralf Veit; Hubert Preissl
Diabetes Care June 2016, Vol.39, 1311-1317. doi:https://doi.org/10.2337/dc16-0094
Prandial Options to Advance Basal Insulin Glargine Therapy: Testing Lixisenatide Plus Basal Insulin Versus Insulin Glulisine Either as Basal-Plus or Basal-Bolus in Type 2 Diabetes: The GetGoal Duo-2 Trial
Julio Rosenstock; on behalf of the GetGoal Duo-2 Trial Investigators; Bruno Guerci; on behalf of the GetGoal Duo-2 Trial Investigators; Markolf Hanefeld; on behalf of the GetGoal Duo-2 Trial Investigators; Sandro Gentile; on behalf of the GetGoal Duo-2 Trial Investigators; Ronnie Aronson; on behalf of the GetGoal Duo-2 Trial Investigators; Francisco J. Tinahones; on behalf of the GetGoal Duo-2 Trial Investigators; Christine Roy-Duval; on behalf of the GetGoal Duo-2 Trial Investigators; Elisabeth Souhami; on behalf of the GetGoal Duo-2 Trial Investigators; Marek Wardecki; on behalf of the GetGoal Duo-2 Trial Investigators; Jenny Ye; on behalf of the GetGoal Duo-2 Trial Investigators; Riccardo Perfetti; on behalf of the GetGoal Duo-2 Trial Investigators; Simon Heller; on behalf of the GetGoal Duo-2 Trial Investigators
Diabetes Care May 2016, Vol.39, 1318-1328. doi:https://doi.org/10.2337/dc16-0014
Predisposing Factors for Any and Major Hypoglycemia With Saxagliptin Versus Placebo and Overall: Analysis From the SAVOR-TIMI 53 Trial
Avivit Cahn; Itamar Raz; Ofri Mosenzon; Gil Leibowitz; Ilan Yanuv; Aliza Rozenberg; Nayyar Iqbal; Boaz Hirshberg; Mikaela Sjostrand; Christina Stahre; KyungAh Im; Estella Kanevsky; Benjamin M. Scirica; Deepak L. Bhatt; Eugene Braunwald
Diabetes Care May 2016, Vol.39, 1329-1337. doi:https://doi.org/10.2337/dc15-2763
Does β-Cell Autoimmunity Play a Role in Cystic Fibrosis–Related Diabetes? Analysis Based on the German/Austrian Diabetes Patienten Verlaufsdokumentation Registry
Katja Konrad; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Thomas Kapellen; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Eggert Lilienthal; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Nicole Prinz; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Maria Bauer; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Angelika Thon; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Ernst Rietschel; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Dagobert Wiemann; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus; Reinhard W. Holl; on behalf of the DPV Initiative and the Competence Network Diabetes Mellitus
Diabetes Care June 2016, Vol.39, 1338-1344. doi:https://doi.org/10.2337/dc16-0020
Association of Weight Loss Maintenance and Weight Regain on 4-Year Changes in CVD Risk Factors: the Action for Health in Diabetes (Look AHEAD) Clinical Trial
Diabetes Care June 2016, Vol.39, 1345-1355. doi:https://doi.org/10.2337/dc16-0509
Long-term Cognitive Implications of Intrauterine Hyperglycemia in Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study)
Birgitte Bytoft; Sine Knorr; Zuzana Vlachova; Rikke B. Jensen; Elisabeth R. Mathiesen; Henning Beck-Nielsen; Claus H. Gravholt; Dorte M. Jensen; Tine D. Clausen; Erik L. Mortensen; Peter Damm
Diabetes Care June 2016, Vol.39, 1356-1363. doi:https://doi.org/10.2337/dc16-0168
Text Message Support for Weight Loss in Patients With Prediabetes: A Randomized Clinical Trial
Henry H. Fischer; Ilana P. Fischer; Rocio I. Pereira; Anna L. Furniss; Jeanne M. Rozwadowski; Susan L. Moore; Michael J. Durfee; Silvia G. Raghunath; Adam G. Tsai; Edward P. Havranek
Diabetes Care February 2016, Vol.39, 1364-1370. doi:https://doi.org/10.2337/dc15-2137
Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation
Ryan T. Crews; Biing-Jiun Shen; Laura Campbell; Peter J. Lamont; Andrew J.M. Boulton; Mark Peyrot; Robert S. Kirsner; Loretta Vileikyte
Diabetes Care June 2016, Vol.39, 1371-1377. doi:https://doi.org/10.2337/dc15-2373
Epidemiology / Health Services Research
Mortality in Type 1 Diabetes in the DCCT/EDIC Versus the General Population
Diabetes Care July 2016, Vol.39, 1378-1383. doi:https://doi.org/10.2337/dc15-2399
Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study
Amélie Bonnefond; Ramsi Keller; David Meyre; Fanny Stutzmann; Dorothée Thuillier; Dimitre G. Stefanov; Philippe Froguel; Fritz F. Horber; John G. Kral
Diabetes Care May 2016, Vol.39, 1384-1392. doi:https://doi.org/10.2337/dc16-0115
Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study
Niina Pitkänen; Markus Juonala; Tapani Rönnemaa; Matthew A. Sabin; Nina Hutri-Kähönen; Mika Kähönen; Terho Lehtimäki; Jorma S.A. Viikari; Olli T. Raitakari
Diabetes Care June 2016, Vol.39, 1393-1399. doi:https://doi.org/10.2337/dc16-0167
Long-term Microvascular Disease Outcomes in Patients With Type 2 Diabetes After Bariatric Surgery: Evidence for the Legacy Effect of Surgery
Karen J. Coleman; Sebastien Haneuse; Eric Johnson; Andy Bogart; David Fisher; Patrick J. O’Connor; Nancy E. Sherwood; Steve Sidney; Mary Kay Theis; Jane Anau; Emily B. Schroeder; Rebecca O’Brien; David Arterburn
Diabetes Care June 2016, Vol.39, 1400-1407. doi:https://doi.org/10.2337/dc16-0194
Emerging Technologies and Therapeutics
Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes
Andres Digenio; Richard L. Dunbar; Veronica J. Alexander; Marcus Hompesch; Linda Morrow; Richard G. Lee; Mark J. Graham; Steven G. Hughes; Rosie Yu; Walter Singleton; Brenda F. Baker; Sanjay Bhanot; Rosanne M. Crooke
Diabetes Care June 2016, Vol.39, 1408-1415. doi:https://doi.org/10.2337/dc16-0126
Cardiovascular and Metabolic Risk
Nonalcoholic Fatty Liver Disease Is Associated With Ventricular Arrhythmias in Patients With Type 2 Diabetes Referred for Clinically Indicated 24-Hour Holter Monitoring
Alessandro Mantovani; Antonio Rigamonti; Stefano Bonapace; Bruna Bolzan; Matteo Pernigo; Giovanni Morani; Lorenzo Franceschini; Corinna Bergamini; Lorenzo Bertolini; Filippo Valbusa; Riccardo Rigolon; Isabella Pichiri; Giacomo Zoppini; Enzo Bonora; Francesco Violi; Giovanni Targher
Diabetes Care May 2016, Vol.39, 1416-1423. doi:https://doi.org/10.2337/dc16-0091
HDL Cholesterol as a Residual Risk Factor for Vascular Events and All-Cause Mortality in Patients With Type 2 Diabetes
Shahnam Sharif; Yolanda van der Graaf; Hendrik M. Nathoe; Harold W. de Valk; Frank L.J. Visseren; Jan Westerink; on behalf of the SMART Study Group
Diabetes Care May 2016, Vol.39, 1424-1430. doi:https://doi.org/10.2337/dc16-0155
The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test Heralds Biomarkers of Type 2 Diabetes Risk in Obese Youth
Joon Young Kim; Sara F. Michaliszyn; Alexis Nasr; SoJung Lee; Hala Tfayli; Tamara Hannon; Kara S. Hughan; Fida Bacha; Silva Arslanian
Diabetes Care June 2016, Vol.39, 1431-1439. doi:https://doi.org/10.2337/dc16-0352
Arterial Stiffness Is Positively Associated With 18F-fluorodeoxyglucose Positron Emission Tomography–Assessed Subclinical Vascular Inflammation in People With Early Type 2 Diabetes
Stefanie A. de Boer; Marieke C. Hovinga-de Boer; Hiddo J.L. Heerspink; Joop D. Lefrandt; Arie M. van Roon; Helen L. Lutgers; Andor W.J.M. Glaudemans; Pieter W. Kamphuisen; Riemer H.J.A. Slart; Douwe J. Mulder
Diabetes Care June 2016, Vol.39, 1440-1447. doi:https://doi.org/10.2337/dc16-0327
Meta-analysis
Metabolic Effects of Monounsaturated Fatty Acid–Enriched Diets Compared With Carbohydrate or Polyunsaturated Fatty Acid–Enriched Diets in Patients With Type 2 Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Diabetes Care July 2016, Vol.39, 1448-1457. doi:https://doi.org/10.2337/dc16-0513
Point-Counterpoint
Are There Clinical Implications of Racial Differences in HbA1c? Yes, to Not Consider Can Do Great Harm!
Diabetes Care July 2016, Vol.39, 1458-1461. doi:https://doi.org/10.2337/dc15-2686
Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference
Diabetes Care July 2016, Vol.39, 1462-1467. doi:https://doi.org/10.2337/dc16-0042
“Prediabetes”: Are There Problems With This Label? Yes, the Label Creates Further Problems!
Diabetes Care July 2016, Vol.39, 1468-1471. doi:https://doi.org/10.2337/dc15-2113
“Prediabetes”: Are There Problems With This Label? No, We Need Heightened Awareness of This Condition!
Diabetes Care July 2016, Vol.39, 1472-1477. doi:https://doi.org/10.2337/dc16-1143
Issues and Events
E-Letters: Observations
Day-and-Night Closed-Loop Control Using the Unified Safety System in Adolescents With Type 1 Diabetes at Camp
Trang T. Ly; Bruce A. Buckingham; Daniel J. DeSalvo; Satya Shanmugham; Marta Satin-Smith; Mark D. DeBoer; Mary C. Oliveri; Elaine Schertz; Marc D. Breton; Daniel R. Cherñavvsky
Diabetes Care June 2016, Vol.39, e106-e107. doi:https://doi.org/10.2337/dc16-0817
An Extra 1,000 Steps Per Day Relates to Improved Cardiovascular Health in Children With Type 1 Diabetes
Jemma Anderson; Jennifer J. Couper; Christine Mpundu-Kaambwa; Lynne C. Giles; Roger Gent; Brian Coppin; Alexia S. Peña
Diabetes Care June 2016, Vol.39, e108-e109. doi:https://doi.org/10.2337/dc16-0526
Impact of Twin Gestation and Fetal Sex on Maternal Risk of Diabetes During and After Pregnancy
Diabetes Care May 2016, Vol.39, e110-e111. doi:https://doi.org/10.2337/dc16-0825
Continuous Glucose Sensor Survival and Accuracy Over 14 Consecutive Days
Daniel J. DeSalvo; Trang T. Ly; R. Paul Wadwa; Laurel Messer; Emily Westfall; Divya Gopisetty; Sarah Hanes; Rie von Eyben; David M. Maahs; Bruce A. Buckingham
Diabetes Care May 2016, Vol.39, e112-e113. doi:https://doi.org/10.2337/dc16-0796
Metformin Therapy and Circulating NT-proBNP Levels: The CAMERA Trial
Diabetes Care June 2016, Vol.39, e114-e115. doi:https://doi.org/10.2337/dc16-0887
Management of Diabetic Ketoacidosis in Severe Insulin Resistance
Diabetes Care June 2016, Vol.39, e116-e118. doi:https://doi.org/10.2337/dc16-0635
Celiac Disease Negatively Influences Lipid Profiles in Young Children With Type 1 Diabetes: Effect of the Gluten-Free Diet
Silvana Salardi; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Giulio Maltoni; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Stefano Zucchini; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Dario Iafusco; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Santino Confetto; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Angela Zanfardino; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Sonia Toni; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Barbara Piccini; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Maximiliano Zioutas; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Marco Marigliano; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Vittoria Cauvin; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Roberto Franceschi; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Ivana Rabbone; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Barbara Predieri; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Riccardo Schiaffini; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Alessandro Salvatoni; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Petra Reinstadler; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Giulia Berioli; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Valentino Cherubini; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED); Giuseppe d’Annunzio; for the Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED)
Diabetes Care June 2016, Vol.39, e119-e120. doi:https://doi.org/10.2337/dc16-0717
Diabetic Ketoacidosis Following Bariatric Surgery in Patients With Type 2 Diabetes
Amin Andalib; Aly Elbahrawy; Saeed Alshlwi; Ahmed Alkhamis; Wen Hu; Sebastian Demyttenaere; Rajesh Aggarwal; Olivier Court
Diabetes Care May 2016, Vol.39, e121-e122. doi:https://doi.org/10.2337/dc16-0280
Effect of Sodium–Glucose Cotransporter 2 Inhibitors on Diabetic Ketoacidosis Among Patients With Type 2 Diabetes: A Meta-analysis of Randomized Controlled Trials
Diabetes Care June 2016, Vol.39, e123-e124. doi:https://doi.org/10.2337/dc16-0885
E-Letters: Comments and Responses
Response to Comment on Koivusalo et al. Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial. Diabetes Care 2016;39:24–30
Diabetes Care July 2016, Vol.39, e126-e127. doi:https://doi.org/10.2337/dci16-0014
Response to Comment on Schwartz et al. The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema. Diabetes Care 2016;39:179–186
Stanley S. Schwartz; Solomon Epstein; Barbara E. Corkey; Struan F.A. Grant; James R. Gavin, III; Richard B. Aguilar
Diabetes Care July 2016, Vol.39, e129-e130. doi:https://doi.org/10.2337/dci16-0011
Comment on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care 2016;39:392–399
Diabetes Care July 2016, Vol.39, e131-e132. doi:https://doi.org/10.2337/dc16-0105
Comment on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care 2016;39:392–399
Diabetes Care July 2016, Vol.39, e133-e134. doi:https://doi.org/10.2337/dc16-0196
Comment on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care 2016;39:392–399
Diabetes Care July 2016, Vol.39, e135. doi:https://doi.org/10.2337/dc16-0176
Response to Comments on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care 2016;39:392–399
Ludwik Fedorko; James M. Bowen; Wilhelmine Jones; George Oreopoulos; Ron Goeree; Robert B. Hopkins; Daria J. O’Reilly
Diabetes Care July 2016, Vol.39, e136-e137. doi:https://doi.org/10.2337/dci16-0006
