Issues

Topics: autoantibodies , diabetes mellitus, type 1 , diabetes mellitus, type 2 , hemoglobin a, glycosylated , insulin

Diabetes Care August 2016, Vol.39, 1479-1480. doi:https://doi.org/10.2337/dc16-ti09

Profiles in Progress

George A. Bray, MD: Progress in Obesity—Multidisciplinary Research, Multidimensional Man

Donna H. Ryan; Barbara C. Hansen; William T. Cefalu

Extract

Topics: obesity

Diabetes Care August 2016, Vol.39, 1481-1485. doi:https://doi.org/10.2337/dc16-1375

Clinical Care / Education / Nutrition / Psychosocial Research

Insulin Injection Into Lipohypertrophic Tissue: Blunted and More Variable Insulin Absorption and Action and Impaired Postprandial Glucose Control

Susanne Famulla; Ulrike Hövelmann; Annelie Fischer; Hans-Veit Coester; Lidia Hermanski; Matthias Kaltheuner; Lars Kaltheuner; Lutz Heinemann; Tim Heise; Laurence Hirsch

Abstracts

Topics: glucose , insulin , insulin administration , process of absorption , glycemic control

Diabetes Care July 2016, Vol.39, 1486-1492. doi:https://doi.org/10.2337/dc16-0610

Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain

Richard W. Simpson; John H. Wlodarczyk

Abstracts

Topics: buprenorphine , pain , neuropathic pain , neuropathic pain, peripheral

Diabetes Care June 2016, Vol.39, 1493-1500. doi:https://doi.org/10.2337/dc16-0123

Once-Daily Liraglutide Versus Lixisenatide as Add-on to Metformin in Type 2 Diabetes: A 26-Week Randomized Controlled Clinical Trial

Michael Nauck; Manfredi Rizzo; Andrew Johnson; Heidrun Bosch-Traberg; Jesper Madsen; Bertrand Cariou

Abstracts

Topics: hemoglobin a, glycosylated , liraglutide , lixisenatide , metformin , diabetes mellitus, type 2

Diabetes Care June 2016, Vol.39, 1501-1509. doi:https://doi.org/10.2337/dc15-2479

Durability of Addition of Roux-en-Y Gastric Bypass to Lifestyle Intervention and Medical Management in Achieving Primary Treatment Goals for Uncontrolled Type 2 Diabetes in Mild to Moderate Obesity: A Randomized Control Trial

Sayeed Ikramuddin; Judith Korner; Wei-Jei Lee; John P. Bantle; Avis J. Thomas; John E. Connett; Daniel B. Leslie; William B. Inabnet, III; Qi Wang; Robert W. Jeffery; Keong Chong; Lee-Ming Chuang; Michael D. Jensen; Adrian Vella; Leaque Ahmed; Kumar Belani; Amy E. Olofson; Heather A. Bainbridge; Charles J. Billington

Abstracts

Topics: adverse event , diabetes mellitus, type 2 , gastric bypass , gastric bypass, roux-en-y , hemoglobin a, glycosylated

Diabetes Care June 2016, Vol.39, 1510-1518. doi:https://doi.org/10.2337/dc15-2481

Elevations in the Fasting Serum Proinsulin–to–C-Peptide Ratio Precede the Onset of Type 1 Diabetes

Emily K. Sims; Zunaira Chaudhry; Renecia Watkins; Farooq Syed; Janice Blum; Fangqian Ouyang; Susan M. Perkins; Raghavendra G. Mirmira; Jay Sosenko; Linda A. DiMeglio; Carmella Evans-Molina

Abstract

Topics: diabetes mellitus, type 1 , fasting , c-peptide , proinsulin , insulin

Diabetes Care July 2016, Vol.39, 1519-1526. doi:https://doi.org/10.2337/dc15-2849

Intensification of Diabetes Therapy and Time Until A1C Goal Attainment Among Patients With Newly Diagnosed Type 2 Diabetes Who Fail Metformin Monotherapy Within a Large Integrated Health System

Kevin M. Pantalone; Brian J. Wells; Kevin M. Chagin; Flavia Ejzykowicz; Changhong Yu; Alex Milinovich; Janine M. Bauman; Michael W. Kattan; Swapnil Rajpathak; Robert S. Zimmerman

Abstract

Topics: clinical inertia , diabetes mellitus, type 2 , metformin , follow-up , early intervention (education)

Diabetes Care August 2016, Vol.39, 1527-1534. doi:https://doi.org/10.2337/dc16-0227

Epidemiology / Health Services Research

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study

Kendra Vehik; Kristian F. Lynch; Desmond A. Schatz; Beena Akolkar; William Hagopian; Marian Rewers; Jin-Xiong She; Olli Simell; Jorma Toppari; Anette-G. Ziegler; Åke Lernmark; Ezio Bonifacio; Jeffrey P. Krischer; the TEDDY Study Group

Abstracts

Topics: autoantibodies , diabetes mellitus, type 1 , child , seroconversion , autoimmunity

Diabetes Care June 2016, Vol.39, 1535-1542. doi:https://doi.org/10.2337/dc16-0181

Association Between Diabetes and Hippocampal Atrophy in Elderly Japanese: The Hisayama Study

Naoki Hirabayashi; Jun Hata; Tomoyuki Ohara; Naoko Mukai; Masaharu Nagata; Mao Shibata; Seiji Gotoh; Yoshihiko Furuta; Fumio Yamashita; Kazufumi Yoshihara; Takanari Kitazono; Nobuyuki Sudo; Yutaka Kiyohara; Toshiharu Ninomiya

Abstract

Topics: cerebral atrophy , deuterium , hippocampal atrophy , magnetic resonance imaging , older adult

Diabetes Care July 2016, Vol.39, 1543-1549. doi:https://doi.org/10.2337/dc15-2800

Changes in Mortality in People With IGT Before and After the Onset of Diabetes During the 23-Year Follow-up of the Da Qing Diabetes Prevention Study

Qiuhong Gong; Ping Zhang; Jinping Wang; Yali An; Edward W. Gregg; Hui Li; Bo Zhang; Ying Shuai; Wenying Yang; Yanyan Chen; Shuqian Liu; Michael M. Engelgau; Yinghua Hu; Peter H. Bennett; Guangwei Li

Abstracts

Topics: diabetes mellitus, type 2 , diabetes prevention , follow-up

Diabetes Care July 2016, Vol.39, 1550-1555. doi:https://doi.org/10.2337/dc16-0429

Diagnosed and Undiagnosed Diabetes Prevalence by County in the U.S., 1999–2012

Laura Dwyer-Lindgren; Johan P. Mackenbach; Frank J. van Lenthe; Abraham D. Flaxman; Ali H. Mokdad

Abstract

Topics: undiagnosed , behavioral risk factor surveillance system

Diabetes Care August 2016, Vol.39, 1556-1562. doi:https://doi.org/10.2337/dc16-0678

Early Prediction of Developing Type 2 Diabetes by Plasma Acylcarnitines: A Population-Based Study

Liang Sun; Liming Liang; Xianfu Gao; Huiping Zhang; Pang Yao; Yao Hu; Yiwei Ma; Feijie Wang; Qianlu Jin; Huaixing Li; Rongxia Li; Yong Liu; Frank B. Hu; Rong Zeng; Xu Lin; Jiarui Wu

Abstracts

Topics: diabetes mellitus, type 2 , fasting blood glucose measurement , plasma , follow-up , insulin

Diabetes Care July 2016, Vol.39, 1563-1570. doi:https://doi.org/10.2337/dc16-0232

A Population-Based Study of All-Cause Mortality and Cardiovascular Disease in Association With Prior History of Hypoglycemia Among Patients With Type 1 Diabetes

Chin-Li Lu; Hsiu-Nien Shen; Susan C. Hu; Jung-Der Wang; Chung-Yi Li

Abstract

Topics: cardiovascular diseases , hypoglycemia , diabetes mellitus, type 1 , hypoglycemic agents

Diabetes Care July 2016, Vol.39, 1571-1578. doi:https://doi.org/10.2337/dc15-2418

Emerging Technologies and Therapeutics

Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Lixisenatide and Insulin Glargine, Versus Insulin Glargine in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy: The LixiLan Proof-of-Concept Randomized Trial

Julio Rosenstock; Michaela Diamant; Vanita R. Aroda; Louise Silvestre; Elisabeth Souhami; Tianyue Zhou; Riccardo Perfetti; Vivian Fonseca; for the LixiLan PoC Study Group

Abstracts

Topics: diabetes mellitus, type 2 , hemoglobin a, glycosylated , insulin glargine , lixisenatide , metformin

Diabetes Care June 2016, Vol.39, 1579-1586. doi:https://doi.org/10.2337/dc16-0046

Pathophysiology / Complications

Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes

James M. Hotaling; Aruna V. Sarma; Darshan P. Patel; Barbara H. Braffett; Patricia A. Cleary; Eva Feldman; William H. Herman; Catherine L. Martin; Alan M. Jacobson; Hunter Wessells; Rodica Pop-Busui; for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group

Abstracts

Topics: dcct trial , diabetes mellitus, type 1 , diabetic autonomic neuropathy , edic trial , urinary incontinence

Diabetes Care June 2016, Vol.39, 1587-1593. doi:https://doi.org/10.2337/dc16-0059

Association of Plasma DPP4 Activity With Mild Cognitive Impairment in Elderly Patients With Type 2 Diabetes: Results From the GDMD Study in China

Tianpeng Zheng; Linyuan Qin; Bo Chen; Xueping Hu; Xiaoxi Zhang; Yihong Liu; Hongbo Liu; Shenghua Qin; Gang Li; Qinghua Li

Abstracts

Topics: diabetes mellitus, type 2 , hemoglobin a, glycosylated , minimal cognitive impairment , older adult , interleukin-6

Diabetes Care July 2016, Vol.39, 1594-1601. doi:https://doi.org/10.2337/dc16-0316

Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series

Abstracts

Topics: arginine test , biological markers , c-peptide , diabetes mellitus, type 2 , glucose

Diabetes Care July 2016, Vol.39, 1602-1613. doi:https://doi.org/10.2337/dc15-0931

Increased Burden of Cerebral Small Vessel Disease in Patients With Type 2 Diabetes and Retinopathy

Jordi Sanahuja; Núria Alonso; Javier Diez; Emilio Ortega; Esther Rubinat; Alícia Traveset; Núria Alcubierre; Àngels Betriu; Esmeralda Castelblanco; Marta Hernández; Francisco Purroy; Maria Vittoria Arcidiacono; Carmen Jurjo; Elvira Fernández; Manuel Puig-Domingo; Per-Henrik Groop; Dídac Mauricio

Abstracts

Topics: brain , diabetes mellitus, type 2 , magnetic resonance imaging , retinal diseases , white matter lesions

Diabetes Care June 2016, Vol.39, 1614-1620. doi:https://doi.org/10.2337/dc15-2671

Cardiovascular and Metabolic Risk

Coprogression of Cardiovascular Risk Factors in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study

The Writing Group for the DCCT/EDIC Research Group

Abstracts

Topics: dcct trial , diabetes mellitus, type 1 , edic trial , follow-up , heart disease risk factors

Diabetes Care July 2016, Vol.39, 1621-1630. doi:https://doi.org/10.2337/dc16-0502

Novel Communications in Diabetes

Optimized Mealtime Insulin Dosing for Fat and Protein in Type 1 Diabetes: Application of a Model-Based Approach to Derive Insulin Doses for Open-Loop Diabetes Management

Kirstine J. Bell; Elena Toschi; Garry M. Steil; Howard A. Wolpert

Abstracts

Topics: insulin , diabetes mellitus, type 1 , glucose , carbohydrates

Diabetes Care July 2016, Vol.39, 1631-1634. doi:https://doi.org/10.2337/dc15-2855

Consensus Report

Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities

Kristen J. Nadeau; Barbara J. Anderson; Erika G. Berg; Jane L. Chiang; Hubert Chou; Kenneth C. Copeland; Tamara S. Hannon; Terry T.-K. Huang; Jane L. Lynch; Jeff Powell; Elizabeth Sellers; William V. Tamborlane; Philip Zeitler

Abstract

Topics: adolescent , diabetes mellitus, type 2

Diabetes Care August 2016, Vol.39, 1635-1642. doi:https://doi.org/10.2337/dc16-1066

Meta-Analysis

Global Estimates on the Number of People Blind or Visually Impaired by Diabetic Retinopathy: A Meta-analysis From 1990 to 2010

Janet L. Leasher; Rupert R.A. Bourne; Seth R. Flaxman; Jost B. Jonas; Jill Keeffe; Kovin Naidoo; Konrad Pesudovs; Holly Price; Richard A. White; Tien Y. Wong; Serge Resnikoff; Hugh R. Taylor; on behalf of the Vision Loss Expert Group of the Global Burden of Disease Study

Abstracts

Topics: blindness , diabetic retinopathy , visual impairment

Diabetes Care August 2016, Vol.39, 1643-1649. doi:https://doi.org/10.2337/dc15-2171

Clinical Images in Diabetes

Diagnostic Dilemma: Clinical and Histological Abnormalities in a Hispanic Patient With Diabetes

Laura M. Jacobsen; Amanda L. Posgai; Martha Campbell-Thompson; Desmond A. Schatz

Extract

Topics: autoantibodies , c-peptide , diabetes mellitus, type 1 , diabetes mellitus, type 2 , donors

Diabetes Care August 2016, Vol.39, 1650-1652. doi:https://doi.org/10.2337/dc16-0711

Erratum

Erratum. Classification and diagnosis of diabetes. Sec. 2. In Standards of Medical Care in Diabetes–2016. Diabetes Care 2016;39(Suppl. 1):S13–S22

American Diabetes Association

Extract

Topics: cardiovascular diseases , chronic venous disease , impaired fasting glucose , prediabetes

Diabetes Care August 2016, Vol.39, 1653. doi:https://doi.org/10.2337/dc16-er09

Issues and Events

Abstracts

Topics: databases , podcasts , standard of care , health personnel

Diabetes Care August 2016, Vol.39, 1654. doi:https://doi.org/10.2337/dc16-ie09

E-Letters: Observations

Carbohydrate Counting at Meal Time Followed by a Small Secondary Postprandial Bolus Injection at 3 Hours Prevents Late Hyperglycemia, Without Hypoglycemia, After a High-Carbohydrate, High-Fat Meal in Type 1 Diabetes

Matthew D. Campbell; Mark Walker; David King; Javier T. Gonzalez; Dean Allerton; Emma J. Stevenson; James A. Shaw; Daniel J. West

Abstracts

Topics: carbohydrates , diabetes mellitus, type 1 , hyperglycemia , hypoglycemia , mealtimes

Diabetes Care June 2016, Vol.39, e141-e142. doi:https://doi.org/10.2337/dc16-0709

Primary Prevention of Sexual Dysfunction With Mediterranean Diet in Type 2 Diabetes: The MÈDITA Randomized Trial

Maria Ida Maiorino; Giuseppe Bellastella; Paolo Chiodini; Ornella Romano; Lorenzo Scappaticcio; Dario Giugliano; Katherine Esposito

Abstracts

Topics: diabetes mellitus, type 2 , mediterranean diet , sexual disorders , sexual dysfunction , primary prevention

Diabetes Care June 2016, Vol.39, e143-e144. doi:https://doi.org/10.2337/dc16-0910

Do Patient Characteristics Impact Decisions by Clinicians on Hemoglobin A_1c Targets?

Saeid Shahraz; Anastassios G. Pittas; Christine M. Lundquist; Goodarz Danaei; David M. Kent

Extract

Topics: hemoglobin a , hemoglobin a, glycosylated

Diabetes Care June 2016, Vol.39, e145-e146. doi:https://doi.org/10.2337/dc16-0532

Secreted Frizzled-Related Protein 4 (SFRP4): A Novel Biomarker of β-Cell Dysfunction and Insulin Resistance in Individuals With Prediabetes and Type 2 Diabetes

Kaviya Anand; Sudha Vidyasagar; Ian Lasrado; Gautam Kumar Pandey; Anandakumar Amutha; Harish Ranjani; Ranjit Mohan Anjana; Viswanathan Mohan; Kuppan Gokulakrishnan

Extract

Topics: biological markers , diabetes mellitus, type 2 , insulin resistance , prediabetes , hemoglobin

Diabetes Care July 2016, Vol.39, e147-e148. doi:https://doi.org/10.2337/dc16-0756

E-Letters: Comments and Responses

Comment on Podmore et al. Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study. Diabetes Care 2016;39:572–581

Luca Mascitelli; Mark R. Goldstein; Leo R. Zacharski

Abstracts

Topics: biological markers , diabetes mellitus, type 2 , iron metabolism , iron

Diabetes Care August 2016, Vol.39, e149-e150. doi:https://doi.org/10.2337/dc16-0538

Comment on Muraki et al. Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies. Diabetes Care 2016;39:376–384

Antonio C. Bossi

Extract

Topics: diabetes mellitus, type 2 , potato , prospective studies

Diabetes Care August 2016, Vol.39, e151. doi:https://doi.org/10.2337/dc16-0434

Response to Comment on Muraki et al. Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies. Diabetes Care 2016;39:376–384

Isao Muraki; Qi Sun

Extract

Topics: diabetes mellitus, type 2 , potato , prospective studies

Diabetes Care August 2016, Vol.39, e152. doi:https://doi.org/10.2337/dci16-0015

Comment on Beltrand et al. Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Diabetes Care 2015;38:2033–2041

Martine Vaxillaire; Amélie Bonnefond; Philippe Froguel

Extract

Topics: mutation , neonatal diabetes mellitus , potassium channel , sulfonylurea compounds

Diabetes Care August 2016, Vol.39, e153-e154. doi:https://doi.org/10.2337/dc15-2703

Response to Comment on Beltrand et al. Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Diabetes Care 2015;38:2033–2041

Jacques Beltrand; Michel Polak

Extract

Topics: mutation , neonatal diabetes mellitus , potassium channel , sulfonylurea compounds

Diabetes Care August 2016, Vol.39, e155. doi:https://doi.org/10.2337/dci16-0002

Comment on Kovatchev and Cobelli. Glucose Variability: Timing, Risk Analysis, and Relationship to Hypoglycemia in Diabetes. Diabetes Care 2016;39:502–510

F. John Service

Extract

Topics: glucose , hypoglycemia

Diabetes Care August 2016, Vol.39, e156. doi:https://doi.org/10.2337/dc16-0841

Response to Comment on Kovatchev and Cobelli. Glucose Variability: Timing, Risk Analysis, and Relationship to Hypoglycemia in Diabetes. Diabetes Care 2016;39:502–510

Boris Kovatchev; Claudio Cobelli

Extract

Topics: glucose , hypoglycemia

Diabetes Care August 2016, Vol.39, e157-e158. doi:https://doi.org/10.2337/dci16-0019

Comment on Yang et al. Association of Statin Use and Reduced Risk of Lower-Extremity Amputation Among Patients With Diabetes: A Nationwide Population-Based Cohort Observation. Diabetes Care 2016;39:e54–e55

Joshua D. Fox; Katherine L. Baquerizo-Nole; Flor Macquhae; Ingrid Herskovitz; Jeremy B. Freedman; Loretta Vileikyte; David J. Margolis; Robert S. Kirsner

Extract

Topics: lower extremity amputation , statins

Diabetes Care August 2016, Vol.39, e159-e160. doi:https://doi.org/10.2337/dc16-0415

Response to Comment on Yang et al. Association of Statin Use and Reduced Risk of Lower-Extremity Amputation Among Patients With Diabetes: A Nationwide Population-Based Cohort Observation. Diabetes Care 2016;39:e54–e55

Tsung-Lin Yang; Liang-Yu Lin; Chin-Chou Huang; Po-Hsun Huang; Shing-Jong Lin; Jaw-Wen Chen; Wan-Leong Chan; Hsin-Bang Leu

Extract