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1 April 2017
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Cover: Hand holding frail old man. Credit: Robert Carter. For more information, please visit gettyimages.com.
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care March 2017, Vol.40, 433-434. doi:https://doi.org/10.2337/dc17-ti04
Profiles in Progress
Emerging Science and Concepts for Management of Diabetes and Aging
Diabetes and Aging: Unique Considerations and Goals of Care
Diabetes Care March 2017, Vol.40, 440-443. doi:https://doi.org/10.2337/dci17-0005
The Pathophysiology of Hyperglycemia in Older Adults: Clinical Considerations
Diabetes Care March 2017, Vol.40, 444-452. doi:https://doi.org/10.2337/dc16-1732
Hemoglobin A1c and Mortality in Older Adults With and Without Diabetes: Results From the National Health and Nutrition Examination Surveys (1988–2011)
Diabetes Care February 2017, Vol.40, 453-460. doi:https://doi.org/10.2337/dci16-0042
Cognitive Dysfunction in Older Adults With Diabetes: What a Clinician Needs to Know
Diabetes Care March 2017, Vol.40, 461-467. doi:https://doi.org/10.2337/dc16-1229
Trends in Drug Utilization, Glycemic Control, and Rates of Severe Hypoglycemia, 2006–2013
Kasia J. Lipska; Xiaoxi Yao; Jeph Herrin; Rozalina G. McCoy; Joseph S. Ross; Michael A. Steinman; Silvio E. Inzucchi; Thomas M. Gill; Harlan M. Krumholz; Nilay D. Shah
Diabetes Care September 2016, Vol.40, 468-475. doi:https://doi.org/10.2337/dc16-0985
Management of Atherosclerotic Cardiovascular Disease Risk Factors in the Older Adult Patient With Diabetes
Diabetes Care March 2017, Vol.40, 476-484. doi:https://doi.org/10.2337/dc16-0815
Lixisenatide Therapy in Older Patients With Type 2 Diabetes Inadequately Controlled on Their Current Antidiabetic Treatment: The GetGoal-O Randomized Trial
Graydon S. Meneilly; Christine Roy-Duval; Hasan Alawi; George Dailey; Diego Bellido; Carlos Trescoli; Helard Manrique Hurtado; Hailing Guo; Valerie Pilorget; Riccardo Perfetti; Hamish Simpson; on behalf of the GetGoal-O Trial Investigators
Diabetes Care February 2017, Vol.40, 485-493. doi:https://doi.org/10.2337/dc16-2143
Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)
M. Angelyn Bethel; for the TECOS Study Group; Samuel S. Engel; for the TECOS Study Group; Jennifer B. Green; for the TECOS Study Group; Zhen Huang; for the TECOS Study Group; Robert G. Josse; for the TECOS Study Group; Keith D. Kaufman; for the TECOS Study Group; Eberhard Standl; for the TECOS Study Group; Shailaja Suryawanshi; for the TECOS Study Group; Frans Van de Werf; for the TECOS Study Group; Darren K. McGuire; for the TECOS Study Group; Eric D. Peterson; for the TECOS Study Group; Rury R. Holman; for the TECOS Study Group
Diabetes Care January 2017, Vol.40, 494-501. doi:https://doi.org/10.2337/dc16-1135
The Impact of Medicare Part D on the Proportion of Out-of-Pocket Prescription Drug Costs Among Older Adults With Diabetes
Diabetes Care November 2016, Vol.40, 502-508. doi:https://doi.org/10.2337/dc16-0902
Management of Inpatient Hyperglycemia and Diabetes in Older Adults
Diabetes Care March 2017, Vol.40, 509-517. doi:https://doi.org/10.2337/dc16-0989
A Proposal for an Out-of-Range Glycemic Population Health Safety Measure for Older Adults With Diabetes
Diabetes Care November 2016, Vol.40, 518-525. doi:https://doi.org/10.2337/dc16-0953
Is HbA1c <7% a Marker of Poor Performance in Individuals >65 Years Old?
Diabetes Care March 2017, Vol.40, 526-528. doi:https://doi.org/10.2337/dci16-0043
Epidemiology / Health Services Research
Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
Diabetes Care January 2017, Vol.40, 529-537. doi:https://doi.org/10.2337/dc16-1958
REPLACE-BG: A Randomized Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Well-Controlled Type 1 Diabetes
Grazia Aleppo; Katrina J. Ruedy; Tonya D. Riddlesworth; Davida F. Kruger; Anne L. Peters; Irl Hirsch; Richard M. Bergenstal; Elena Toschi; Andrew J. Ahmann; Viral N. Shah; Michael R. Rickels; Bruce W. Bode; Athena Philis-Tsimikas; Rodica Pop-Busui; Henry Rodriguez; Emily Eyth; Anuj Bhargava; Craig Kollman; Roy W. Beck; for the REPLACE-BG Study Group
Diabetes Care February 2017, Vol.40, 538-545. doi:https://doi.org/10.2337/dc16-2482
Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes
Ravi Shah; Venkatesh Murthy; Michael Pacold; Kirsty Danielson; Kahraman Tanriverdi; Martin G. Larson; Kristina Hanspers; Alexander Pico; Eric Mick; Jared Reis; Sarah de Ferranti; Elizaveta Freinkman; Daniel Levy; Udo Hoffmann; Stavroula Osganian; Saumya Das; Jane E. Freedman
Diabetes Care February 2017, Vol.40, 546-553. doi:https://doi.org/10.2337/dc16-1354
Emerging Technologies and Therapeutics
Comparison of Insulin Glargine 300 Units/mL and 100 Units/mL in Adults With Type 1 Diabetes: Continuous Glucose Monitoring Profiles and Variability Using Morning or Evening Injections
Richard M. Bergenstal; Timothy S. Bailey; David Rodbard; Monika Ziemen; Hailing Guo; Isabel Muehlen-Bartmer; Andrew J. Ahmann
Diabetes Care January 2017, Vol.40, 554-560. doi:https://doi.org/10.2337/dc16-0684
Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development
Maria Acevedo-Calado; Eddie A. James; Michael P. Morran; Susan L. Pietropaolo; Qin Ouyang; David Arribas-Layton; Marco Songini; Marco Liguori; Anna Casu; Richard J. Auchus; Shuai Huang; Liping Yu; Aaron Michels; Roberto Gianani; Massimo Pietropaolo
Diabetes Care February 2017, Vol.40, 561-568. doi:https://doi.org/10.2337/dc16-1527
Pathophysiology / Complications
Proinflammatory Cytokines Predict the Incidence and Progression of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study
Christian Herder; Julia M. Kannenberg; Cornelia Huth; Maren Carstensen-Kirberg; Wolfgang Rathmann; Wolfgang Koenig; Margit Heier; Sonja Püttgen; Barbara Thorand; Annette Peters; Michael Roden; Christa Meisinger; Dan Ziegler
Diabetes Care February 2017, Vol.40, 569-576. doi:https://doi.org/10.2337/dc16-2259
Serum Trypsinogen Levels in Type 1 Diabetes
Xia Li; Martha Campbell-Thompson; Clive H. Wasserfall; Kieran McGrail; Amanda Posgai; Andrew R. Schultz; Todd M. Brusko; Jonathan Shuster; Faming Liang; Andrew Muir; Desmond Schatz; Michael J. Haller; Mark A. Atkinson
Diabetes Care January 2017, Vol.40, 577-582. doi:https://doi.org/10.2337/dc16-1774
Relationships Between Type 2 Diabetes, Neuropathy, and Microvascular Dysfunction: Evidence From Patients With Cryptogenic Axonal Polyneuropathy
Anna L. Emanuel; Mariska D. Nieuwenhoff; Erica S. Klaassen; Ajay Verma; Mark H.H. Kramer; Rob Strijers; Alexander F.J.E. Vrancken; Etto Eringa; Geert Jan Groeneveld; Erik H. Serné
Diabetes Care February 2017, Vol.40, 583-590. doi:https://doi.org/10.2337/dc16-1690
Cardiovascular and Metabolic Risk
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study
Aramesh Saremi; Scott Howell; Dawn C. Schwenke; Gideon Bahn; Paul J. Beisswenger; Peter D. Reaven; for the VADT Investigators
Diabetes Care February 2017, Vol.40, 591-598. doi:https://doi.org/10.2337/dc16-1875
Nondiabetic Glucometabolic Status and Progression of Aortic Stiffness: The Whitehall II Study
Carmel M. McEniery; Ian B. Wilkinson; Nanna B. Johansen; Daniel R. Witte; Archana Singh-Manoux; Mika Kivimaki; Adam G. Tabak; Eric J. Brunner; Martin J. Shipley
Diabetes Care January 2017, Vol.40, 599-606. doi:https://doi.org/10.2337/dc16-1773
Predictors of Dyslipidemia Over Time in Youth With Type 1 Diabetes: For the SEARCH for Diabetes in Youth Study
Amy S. Shah; David M. Maahs; Jeanette M. Stafford; Lawrence M. Dolan; Wei Lang; Giuseppina Imperatore; Ronny A. Bell; Angela D. Liese; Kristi Reynolds; Catherine Pihoker; Santica Marcovina; Ralph B. D’Agostino, Jr.; Dana Dabelea
Diabetes Care January 2017, Vol.40, 607-613. doi:https://doi.org/10.2337/dc16-2193
Meta-analysis
Insulin and Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Type 2 Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Maria Ida Maiorino; Paolo Chiodini; Giuseppe Bellastella; Annalisa Capuano; Katherine Esposito; Dario Giugliano
Diabetes Care March 2017, Vol.40, 614-624. doi:https://doi.org/10.2337/dc16-1957
Errata
Erratum. The Use of Anthropometric Measures for Cardiometabolic Risk Identification in a Rural African Population. Diabetes Care 2013;37:e64–e65
Georgina A.V. Murphy; Gershim Asiki; Rebecca N. Nsubuga; Elizabeth H. Young; Janet Seeley; Manjinder S. Sandhu; Anatoli Kamali
Diabetes Care January 2017, Vol.40, 625. doi:https://doi.org/10.2337/dc17-er04a
Erratum. Clinical Course of Myocardial Infarction Among Diabetic Patients. Diabetes Care 1980;3:526–529
Diabetes Care January 2017, Vol.40, 625. doi:https://doi.org/10.2337/dc17-er04b
Issues and Events
e-Letters
Observations
Poor Adherence to Ketone Testing in Patients With Type 1 Diabetes
Anastasia Albanese-O’Neill; for the T1D Exchange Clinic Network; Mengdi Wu; for the T1D Exchange Clinic Network; Kellee M. Miller; for the T1D Exchange Clinic Network; Laura Jacobsen; for the T1D Exchange Clinic Network; Michael J. Haller; for the T1D Exchange Clinic Network; Desmond Schatz; for the T1D Exchange Clinic Network
Diabetes Care January 2017, Vol.40, e38-e39. doi:https://doi.org/10.2337/dc16-2620
Potential Hypoxic Renal Injury in Patients With Diabetes on SGLT2 Inhibitors: Caution Regarding Concomitant Use of NSAIDs and Iodinated Contrast Media
Diabetes Care January 2017, Vol.40, e40-e41. doi:https://doi.org/10.2337/dc16-2200
Metabolic Consequences of Restorative Surgery After Gastric Bypass
Diabetes Care February 2017, Vol.40, e42-e43. doi:https://doi.org/10.2337/dc16-2561
Five-Year Outcomes of a Randomized Trial of Gastric Band Surgery in Overweight but Not Obese People With Type 2 Diabetes
Diabetes Care February 2017, Vol.40, e44-e45. doi:https://doi.org/10.2337/dc16-2149
Comments and Responses
Response to Comment on Inzucchi et al. Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Diabetes Care 2016;39:1684–1692
Silvio E. Inzucchi; for the IRIS Trial Investigators; Catherine M. Viscoli; for the IRIS Trial Investigators; Lawrence H. Young; for the IRIS Trial Investigators; Karen L. Furie; for the IRIS Trial Investigators; Mark Gorman; for the IRIS Trial Investigators; Anne M. Lovejoy; for the IRIS Trial Investigators; Samuel Dagogo-Jack; for the IRIS Trial Investigators; Faramarz Ismail-Beigi; for the IRIS Trial Investigators; Mary T. Korytkowski; for the IRIS Trial Investigators; Richard E. Pratley; for the IRIS Trial Investigators; Gregory G. Schwartz; for the IRIS Trial Investigators; Walter N. Kernan; for the IRIS Trial Investigators
Diabetes Care March 2017, Vol.40, e47-e48. doi:https://doi.org/10.2337/dci16-0048
