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August 2018
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care July 2018, Vol.41, 1541-1542. doi:https://doi.org/10.2337/dc18-ti08
Perspectives in Care
SGLT2 Inhibitors in Combination Therapy: From Mechanisms to Clinical Considerations in Type 2 Diabetes Management
Michaël J.B. van Baar; Charlotte C. van Ruiten; Marcel H.A. Muskiet; Liselotte van Bloemendaal; Richard G. IJzerman; Daniël H. van Raalte
Diabetes Care July 2018, Vol.41, 1543-1556. doi:https://doi.org/10.2337/dc18-0588
Commentaries
Primum Non Nocere: Refocusing Our Attention on Severe Hypoglycemia Prevention
Diabetes Care July 2018, Vol.41, 1557-1559. doi:https://doi.org/10.2337/dci18-0020
Can We RISE to the Challenge of Youth-Onset Type 2 Diabetes?
Diabetes Care June 2018, Vol.41, 1560-1562. doi:https://doi.org/10.2337/dci18-0025
Diabetes Care Symposium
Intensive Glycemic Treatment During Type 1 Diabetes Pregnancy: A Story of (Mostly) Sweet Success!
Diabetes Care June 2018, Vol.41, 1563-1571. doi:https://doi.org/10.2337/dci18-0001
Closing the Loop on Managing Youth With Type 1 Diabetes: Children Are Not Just Small Adults
Diabetes Care June 2018, Vol.41, 1572-1578. doi:https://doi.org/10.2337/dci18-0003
Diabetes Technology Update: Use of Insulin Pumps and Continuous Glucose Monitoring in the Hospital
Diabetes Care June 2018, Vol.41, 1579-1589. doi:https://doi.org/10.2337/dci18-0002
Clinical Care / Education / Nutrition / Psychosocial Research
Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts
Erin S. LeBlanc; Richard E. Pratley; Bess Dawson-Hughes; Myrlene A. Staten; Patricia R. Sheehan; Michael R. Lewis; Anne Peters; Sun H. Kim; Ranee Chatterjee; Vanita R. Aroda; Chhavi Chadha; Lisa M. Neff; Irwin G. Brodsky; Clifford Rosen; Cyrus V. Desouza; John P. Foreyt; Daniel S. Hsia; Karen C. Johnson; Philip Raskin; Sangeeta R. Kashyap; Patrick O’Neil; Lawrence S. Phillips; Neda Rasouli; Emilia P. Liao; David C. Robbins; Anastassios G. Pittas; D2d Research Group
Diabetes Care June 2018, Vol.41, 1590-1599. doi:https://doi.org/10.2337/dc18-0240
Sustained Reduction in Severe Hypoglycemia in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: Two-Year Follow-up in the HypoCOMPaSS Randomized Clinical Trial
Stuart A. Little; Jane Speight; Lalantha Leelarathna; Emma Walkinshaw; Horng Kai Tan; Anita Bowes; Alexandra Lubina-Solomon; Thomas J. Chadwick; Deborah D. Stocken; Catherine Brennand; Sally M. Marshall; Ruth Wood; David Kerr; Daniel Flanagan; Simon R. Heller; Mark L. Evans; James A.M. Shaw
Diabetes Care April 2018, Vol.41, 1600-1607. doi:https://doi.org/10.2337/dc17-2682
Type 1 Diabetes Self-Management From Emerging Adulthood Through Older Adulthood
Diabetes Care May 2018, Vol.41, 1608-1614. doi:https://doi.org/10.2337/dc17-2597
Dietary Patterns Over Time and Microalbuminuria in Youth and Young Adults With Type 1 Diabetes: The SEARCH Nutrition Ancillary Study
Tina Costacou; Jamie Crandell; Anna R. Kahkoska; Angela D. Liese; Dana Dabelea; Jean M. Lawrence; David J. Pettitt; Kristi Reynolds; Elizabeth J. Mayer-Davis; Amy K. Mottl
Diabetes Care June 2018, Vol.41, 1615-1622. doi:https://doi.org/10.2337/dc18-0319
Preventing Diabetes Distress in Adolescents With Type 1 Diabetes: Results 1 Year After Participation in the STePS Program
Diabetes Care June 2018, Vol.41, 1623-1630. doi:https://doi.org/10.2337/dc17-2556
Epidemiology / Health Services Research
Health Care Utilization and Burden of Diabetic Ketoacidosis in the U.S. Over the Past Decade: A Nationwide Analysis
Diabetes Care May 2018, Vol.41, 1631-1638. doi:https://doi.org/10.2337/dc17-1379
Ambulatory Medication Reconciliation and Frequency of Hospitalizations and Emergency Department Visits in Patients With Diabetes
Alexander Turchin; Olukayode Sosina; Huabing Zhang; Maria Shubina; Sonali P. Desai; Donald C. Simonson; Marcia A. Testa
Diabetes Care June 2018, Vol.41, 1639-1645. doi:https://doi.org/10.2337/dc17-1260
Diabetes and Trajectories of Estimated Glomerular Filtration Rate: A Prospective Cohort Analysis of the Atherosclerosis Risk in Communities Study
Bethany Warren; Casey M. Rebholz; Yingying Sang; Alexandra K. Lee; Josef Coresh; Elizabeth Selvin; Morgan E. Grams
Diabetes Care June 2018, Vol.41, 1646-1653. doi:https://doi.org/10.2337/dc18-0277
Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study
Stephanie Brinkhues; Nicole H.T.M. Dukers-Muijrers; Christian J.P.A. Hoebe; Carla J.H. van der Kallen; Annemarie Koster; Ronald M.A. Henry; Coen D.A. Stehouwer; Paul H.M. Savelkoul; Nicolaas C. Schaper; Miranda T. Schram
Diabetes Care June 2018, Vol.41, 1654-1662. doi:https://doi.org/10.2337/dc17-2144
Emerging Therapies: Drugs and Regimens
Neoplasms Reported With Liraglutide or Placebo in People With Type 2 Diabetes: Results From the LEADER Randomized Trial
Michael A. Nauck; Thomas Jon Jensen; Carina Rosenkilde; Salvatore Calanna; John B. Buse; the LEADER Publication Committee on behalf of the LEADER Trial Investigators
Diabetes Care June 2018, Vol.41, 1663-1671. doi:https://doi.org/10.2337/dc17-1825
A Randomized Controlled Trial Comparing Efficacy and Safety of Insulin Glargine 300 Units/mL Versus 100 Units/mL in Older People With Type 2 Diabetes: Results From the SENIOR Study
Robert Ritzel; Stewart B. Harris; Helen Baron; Hermes Florez; Ronan Roussel; Melanie Espinasse; Isabel Muehlen-Bartmer; Nianxian Zhang; Monica Bertolini; Claire Brulle-Wohlhueter; Medha Munshi; Geremia B. Bolli
Diabetes Care June 2018, Vol.41, 1672-1680. doi:https://doi.org/10.2337/dc18-0168
Emerging Technologies: Data Systems and Devices
Investigation of the Accuracy of 18 Marketed Blood Glucose Monitors
David C. Klonoff; Joan Lee Parkes; Boris P. Kovatchev; David Kerr; Wendy C. Bevier; Ronald L. Brazg; Mark Christiansen; Timothy S. Bailey; James H. Nichols; Michael A. Kohn
Diabetes Care June 2018, Vol.41, 1681-1688. doi:https://doi.org/10.2337/dc17-1960
Pathophysiology / Complications
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes
Nordin M.J. Hanssen; Jan Westerink; Jean L.J.M. Scheijen; Yolanda van der Graaf; Coen D.A. Stehouwer; Casper G. Schalkwijk; SMART Study Group
Diabetes Care May 2018, Vol.41, 1689-1695. doi:https://doi.org/10.2337/dc18-0159
Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: I. Observations Using the Hyperglycemic Clamp
Diabetes Care June 2018, Vol.41, 1696-1706. doi:https://doi.org/10.2337/dc18-0244
Impact of Insulin and Metformin Versus Metformin Alone on β-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes
Diabetes Care June 2018, Vol.41, 1717-1725. doi:https://doi.org/10.2337/dc18-0787
Mexican Carriers of the HNF1A p.E508K Variant Do Not Experience an Enhanced Response to Sulfonylureas
Alexandro J. Martagón; Omar Yaxmehen Bello-Chavolla; Olimpia Arellano-Campos; Paloma Almeda-Valdés; Geoffrey A. Walford; Ivette Cruz-Bautista; Donají V. Gómez-Velasco; Roopa Mehta; Liliana Muñoz-Hernández; Magdalena Sevilla-González; Tannia L. Viveros-Ruiz; María Luisa Ordoñez-Sánchez; Rosario Rodríguez-Guillen; Jose C. Florez; María Teresa Tusié-Luna; Carlos A. Aguilar-Salinas; Slim Initiative in Genomic Medicine for the Americas (SIGMA) Type 2 Diabetes Consortium
Diabetes Care May 2018, Vol.41, 1726-1731. doi:https://doi.org/10.2337/dc18-0384
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
Panu K. Luukkonen; Sanja Sädevirta; You Zhou; Brandon Kayser; Ashfaq Ali; Linda Ahonen; Susanna Lallukka; Véronique Pelloux; Melania Gaggini; Ching Jian; Antti Hakkarainen; Nina Lundbom; Helena Gylling; Anne Salonen; Matej Orešič; Tuulia Hyötyläinen; Marju Orho-Melander; Aila Rissanen; Amalia Gastaldelli; Karine Clément; Leanne Hodson; Hannele Yki-Järvinen
Diabetes Care May 2018, Vol.41, 1732-1739. doi:https://doi.org/10.2337/dc18-0071
Pathophysiological Characteristics Underlying Different Glucose Response Curves: A Latent Class Trajectory Analysis From the Prospective EGIR-RISC Study
Adam Hulman; Daniel R. Witte; Dorte Vistisen; Beverley Balkau; Jacqueline M. Dekker; Christian Herder; Mensud Hatunic; Thomas Konrad; Kristine Færch; Melania Manco
Diabetes Care May 2018, Vol.41, 1740-1748. doi:https://doi.org/10.2337/dc18-0279
Cognitive Function Deficits Associated With Long-Duration Type 1 Diabetes and Vascular Complications
Gail Musen; Liane J. Tinsley; Katrina A. Marcinkowski; David Pober; Jennifer K. Sun; Maya Khatri; Richie Huynh; Annie Lu; George L. King; Hillary A. Keenan
Diabetes Care June 2018, Vol.41, 1749-1756. doi:https://doi.org/10.2337/dc17-1955
Effect of Aspirin on Cancer Chemoprevention in Japanese Patients With Type 2 Diabetes: 10-Year Observational Follow-up of a Randomized Controlled Trial
Sadanori Okada; Takeshi Morimoto; Hisao Ogawa; Mio Sakuma; Chisa Matsumoto; Hirofumi Soejima; Masafumi Nakayama; Naofumi Doi; Hideaki Jinnouchi; Masako Waki; Izuru Masuda; Yoshihiko Saito; JPAD Trial Investigators
Diabetes Care June 2018, Vol.41, 1757-1764. doi:https://doi.org/10.2337/dc18-0368
Identification of Novel Urinary Biomarkers for Predicting Renal Prognosis in Patients With Type 2 Diabetes by Glycan Profiling in a Multicenter Prospective Cohort Study: U-CARE Study 1
Koki Mise; Mariko Imamura; Satoshi Yamaguchi; Sanae Teshigawara; Atsuhito Tone; Haruhito A. Uchida; Jun Eguchi; Atsuko Nakatsuka; Daisuke Ogawa; Michihiro Yoshida; Masao Yamada; Kenichi Shikata; Jun Wada
Diabetes Care June 2018, Vol.41, 1765-1775. doi:https://doi.org/10.2337/dc18-0030
Cardiovascular and Metabolic Risk
National Rates of Initiation and Intensification of Antidiabetic Therapy Among Patients With Commercial Insurance
Diabetes Care May 2018, Vol.41, 1776-1782. doi:https://doi.org/10.2337/dc17-2585
Hypoglycemia, Cardiovascular Outcomes, and Death: The LEADER Experience
Bernard Zinman; Steven P. Marso; Erik Christiansen; Salvatore Calanna; Søren Rasmussen; John B. Buse; the LEADER Publication Committee on behalf of the LEADER Trial Investigators
Diabetes Care June 2018, Vol.41, 1783-1791. doi:https://doi.org/10.2337/dc17-2677
Adiponectin, Free Fatty Acids, and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Acute Coronary Syndrome
Ilse C. Schrieks; Anna Nozza; Barbara E. Stähli; John B. Buse; Robert R. Henry; Klas Malmberg; Bruce Neal; Stephen J. Nicholls; Lars Rydén; Linda Mellbin; Anders Svensson; Hans Wedel; Arlette Weichert; A. Michael Lincoff; Jean-Claude Tardif; Diederick E. Grobbee; Gregory G. Schwartz
Diabetes Care June 2018, Vol.41, 1792-1800. doi:https://doi.org/10.2337/dc18-0158
Effect of Empagliflozin on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial (E-LIFT Trial)
Mohammad Shafi Kuchay; Sonal Krishan; Sunil Kumar Mishra; Khalid Jamal Farooqui; Manish Kumar Singh; Jasjeet Singh Wasir; Beena Bansal; Parjeet Kaur; Ganesh Jevalikar; Harmendeep Kaur Gill; Narendra Singh Choudhary; Ambrish Mithal
Diabetes Care June 2018, Vol.41, 1801-1808. doi:https://doi.org/10.2337/dc18-0165
Novel Communications in Diabetes
Effects of Pentoxifylline on Soluble Klotho Concentrations and Renal Tubular Cell Expression in Diabetic Kidney Disease
Juan F. Navarro-González; María Dolores Sánchez-Niño; Javier Donate-Correa; Ernesto Martín-Núñez; Carla Ferri; Nayra Pérez-Delgado; José Luis Górriz; Alberto Martínez-Castelao; Alberto Ortiz; Carmen Mora-Fernández
Diabetes Care June 2018, Vol.41, 1817-1820. doi:https://doi.org/10.2337/dc18-0078
Review
Large-for-Gestational-Age Neonates in Type 1 Diabetes and Pregnancy: Contribution of Factors Beyond Hyperglycemia
Diabetes Care July 2018, Vol.41, 1821-1828. doi:https://doi.org/10.2337/dc18-0551
Images in Clinical Diabetes
Visual Inspection of Chromatograms Assists Interpretation of HbA1c: A Case Report
Diabetes Care July 2018, Vol.41, 1829-1830. doi:https://doi.org/10.2337/dc18-0378
Erratum
Erratum. Insulin Access and Affordability Working Group: Conclusions and Recommendations. Diabetes Care 2018;41;1299–1311
William T. Cefalu; on behalf of the Insulin Access and Affordability Working Group; Daniel E. Dawes; on behalf of the Insulin Access and Affordability Working Group; Gina Gavlak; on behalf of the Insulin Access and Affordability Working Group; Dana Goldman; on behalf of the Insulin Access and Affordability Working Group; William H. Herman; on behalf of the Insulin Access and Affordability Working Group; Karen Van Nuys; on behalf of the Insulin Access and Affordability Working Group; Alvin C. Powers; on behalf of the Insulin Access and Affordability Working Group; Simeon I. Taylor; on behalf of the Insulin Access and Affordability Working Group; Alan L. Yatvin; on behalf of the Insulin Access and Affordability Working Group
Diabetes Care July 2018, Vol.41, 1831. doi:https://doi.org/10.2337/dc18-er08
Issues and Events
e-Letters
Observations
Acute Effect of Empagliflozin on Fractional Excretion of Sodium and eGFR in Youth With Type 2 Diabetes
Petter Bjornstad; Lori Laffel; William V. Tamborlane; Gudrun Simons; Stefan Hantel; Maximilian von Eynatten; Jyothis George; Jan Marquard; David Z.I. Cherney
Diabetes Care June 2018, Vol.41, e129-e130. doi:https://doi.org/10.2337/dc18-0394
