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April 2019
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Topics:
diabetes mellitus, type 1
,
insulin
,
insulin infusion systems
,
metformin
,
diabetes prevention
Diabetes Care March 2019, Vol.42, 497-498. doi:https://doi.org/10.2337/dc19-ti04
Commentary
More Evidence for a Prevention-Related Indication for Metformin: Let the Arguments Resume!
Diabetes Care March 2019, Vol.42, 499-501. doi:https://doi.org/10.2337/dci18-0062
Profiles in Progress
Elizabeth Barrett-Connor: Instrumental Contributor to the Understanding of Midlife Well-being and Health in Both Women and Men
Diabetes Care March 2019, Vol.42, 502-506. doi:https://doi.org/10.2337/dci19-0004
Clinical Care / Education / Nutrition / Psychosocial Research
Frailty and Risk of Fractures in Patients With Type 2 Diabetes
Guowei Li; Jerilynn C. Prior; William D. Leslie; Lehana Thabane; Alexandra Papaioannou; Robert G. Josse; Stephanie M. Kaiser; Christopher S. Kovacs; Tassos Anastassiades; Tanveer Towheed; K. Shawn Davison; Mitchell Levine; David Goltzman; Jonathan D. Adachi; for the CaMos Research Group
Topics:
diabetes mellitus, type 2
,
fractures
,
frailty
,
osteoporotic fracture risk
Diabetes Care January 2019, Vol.42, 507-513. doi:https://doi.org/10.2337/dc18-1965
Overall Quality of Care Predicts the Variability of Key Risk Factors for Complications in Type 2 Diabetes: An Observational, Longitudinal Retrospective Study
Antonio Ceriello; Maria Chiara Rossi; Salvatore De Cosmo; Giuseppe Lucisano; Roberto Pontremoli; Paola Fioretto; Carlo Giorda; Antonio Pacilli; Francesca Viazzi; Giuseppina Russo; Antonio Nicolucci; on behalf of the AMD-Annals Study Group
Topics:
blood pressure
,
diabetes mellitus, type 2
,
hemoglobin a, glycosylated
,
high density lipoprotein cholesterol
,
ldl cholesterol lipoproteins
Diabetes Care February 2019, Vol.42, 514-519. doi:https://doi.org/10.2337/dc18-1471
Comparative Effects of Proximal and Distal Small Intestinal Glucose Exposure on Glycemia, Incretin Hormone Secretion, and the Incretin Effect in Health and Type 2 Diabetes
Xiang Zhang; Richard L. Young; Michelle Bound; Sanyuan Hu; Karen L. Jones; Michael Horowitz; Christopher K. Rayner; Tongzhi Wu
Topics:
diabetes mellitus, type 2
,
glucagon-like peptide 1
,
glucose
,
incretin
,
infusion procedures
Diabetes Care February 2019, Vol.42, 520-528. doi:https://doi.org/10.2337/dc18-2156
Effects of Light Therapy on Mood and Insulin Sensitivity in Patients With Type 2 Diabetes and Depression: Results From a Randomized Placebo-Controlled Trial
Annelies Brouwer; Daniel H. van Raalte; Hoang-Ton Nguyen; Femke Rutters; Peter M. van de Ven; Petra J.M. Elders; Annette C. Moll; Eus J.W. Van Someren; Frank J. Snoek; Aartjan T.F. Beekman; Marijke A. Bremmer
Topics:
depressive disorders
,
diabetes mellitus, type 2
,
insulin sensitivity
,
phototherapy
,
ultraviolet therapy
Diabetes Care March 2019, Vol.42, 529-538. doi:https://doi.org/10.2337/dc18-1732
Epidemiology / Health Services Research
Cumulative Risk of End-Stage Renal Disease Among Patients With Type 2 Diabetes: A Nationwide Inception Cohort Study
Patrik Finne; Per-Henrik Groop; Martti Arffman; Marjo Kervinen; Jaakko Helve; Carola Grönhagen-Riska; Reijo Sund
Diabetes Care January 2019, Vol.42, 539-544. doi:https://doi.org/10.2337/dc18-1485
Real-World Costs of Continuous Insulin Pump Therapy and Multiple Daily Injections for Type 1 Diabetes: A Population-Based and Propensity-Matched Cohort From the Swedish National Diabetes Register
Emilie Toresson Grip; Ann-Marie Svensson; Mervete Miftaraj; Björn Eliasson; Stefan Franzén; Soffia Gudbjörnsdottir; Katarina Steen Carlsson
Diabetes Care January 2019, Vol.42, 545-552. doi:https://doi.org/10.2337/dc18-1850
Maternal and Newborn Vitamin D–Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
German Tapia; Karl Mårild; Sandra R. Dahl; Nicolai A. Lund-Blix; Marte K. Viken; Benedicte A. Lie; Pål R. Njølstad; Geir Joner; Torild Skrivarhaug; Arieh S. Cohen; Ketil Størdal; Lars C. Stene
Topics:
child
,
diabetes mellitus, type 1
,
genotype
,
pregnancy
,
umbilical cord blood
Diabetes Care January 2019, Vol.42, 553-559. doi:https://doi.org/10.2337/dc18-2176
The Impact of Obesity on the Incidence of Type 2 Diabetes Among Women With Polycystic Ovary Syndrome
Diabetes Care January 2019, Vol.42, 560-567. doi:https://doi.org/10.2337/dc18-1738
Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study
Linda E.T. Vissers; Ivonne Sluijs; Yvonne T. van der Schouw; Nita G. Forouhi; Fumiaki Imamura; Stephen Burgess; Aurelio Barricarte; Heiner Boeing; Catalina Bonet; Maria-Dolores Chirlaque; Guy Fagherazzi; Paul W. Franks; Heinz Freisling; Marc J. Gunter; J. Ramón Quirós; Daniel B. Ibsen; Rudolf Kaaks; Timothy Key; Kay T. Khaw; Tilman Kühn; Olatz Mokoroa; Peter M. Nilsson; Kim Overvad; Valeria Pala; Domenico Palli; Salvatore Panico; Carlotta Sacerdote; Annemieke M.W. Spijkerman; Anne Tjonneland; Rosario Tumino; Miguel Rodríguez-Barranco; Olov Rolandsson; Elio Riboli; Stephen J. Sharp; Claudia Langenberg; Nicholas J. Wareham
Topics:
dairy products
,
diabetes mellitus, type 2
,
diet
,
genotype determination
,
milk
Diabetes Care February 2019, Vol.42, 568-575. doi:https://doi.org/10.2337/dc18-2034
Changes in Screening Practices for Prediabetes and Diabetes Since the Recommendation for Hemoglobin A1c Testing
Topics:
glucose
,
glucose measurement
,
hemoglobin a, glycosylated
,
prediabetes
,
screening
Diabetes Care February 2019, Vol.42, 576-584. doi:https://doi.org/10.2337/dc17-1726
Emerging Therapies: Drugs and Regimens
Antisense Inhibition of Glucagon Receptor by IONIS-GCGRRx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy
Erin S. Morgan; Li-Jung Tai; Nguyen C. Pham; Julia K. Overman; Lynnetta M. Watts; Anne Smith; Shiangtung W. Jung; Martin Gajdošík; Martin Krššák; Michael Krebs; Richard S. Geary; Brenda F. Baker; Sanjay Bhanot
Topics:
diabetes mellitus, type 2
,
gcgr gene
,
hemoglobin a, glycosylated
,
lipids
,
liver glycogen
Diabetes Care February 2019, Vol.42, 585-593. doi:https://doi.org/10.2337/dc18-1343
Emerging Technologies: Data Systems and Devices
Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial
Martin Tauschmann; Janet M. Allen; Katrin Nagl; Maria Fritsch; James Yong; Emily Metcalfe; Dominique Schaeffer; Muriel Fichelle; Ulrike Schierloh; Alena G. Thiele; Daniela Abt; Harald Kojzar; Julia K. Mader; Sonja Slegtenhorst; Nicole Barber; Malgorzata E. Wilinska; Charlotte Boughton; Gianluca Musolino; Judy Sibayan; Nathan Cohen; Craig Kollman; Sabine E. Hofer; Elke Fröhlich-Reiterer; Thomas M. Kapellen; Carlo L. Acerini; Carine de Beaufort; Fiona Campbell; Birgit Rami-Merhar; Roman Hovorka; on behalf of KidsAP Consortium
Diabetes Care January 2019, Vol.42, 594-600. doi:https://doi.org/10.2337/dc18-1881
Pathophysiology / Complications
Long-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study
Topics:
hemoglobin a, glycosylated
,
metformin
,
glucose
,
diabetes prevention
,
fasting blood glucose measurement
Diabetes Care March 2019, Vol.42, 601-608. doi:https://doi.org/10.2337/dc18-1970
Impact of Age of Onset, Puberty, and Glycemic Control Followed From Diagnosis on Incidence of Retinopathy in Type 1 Diabetes: The VISS Study
Topics:
diabetic retinopathy
,
proliferative diabetic retinopathy
,
puberty
,
retinal diseases
,
hemoglobin a, glycosylated
Diabetes Care January 2019, Vol.42, 609-616. doi:https://doi.org/10.2337/dc18-1950
Effect of Glucose Improvement on Spirometric Maneuvers in Patients With Type 2 Diabetes: The Sweet Breath Study
Liliana Gutiérrez-Carrasquilla; Enric Sánchez; Ferran Barbé; Mireia Dalmases; Carolina López-Cano; Marta Hernández; Ferran Rius; Paola Carmona; Cristina Hernández; Rafael Simó; Albert Lecube
Topics:
diabetes mellitus, type 2
,
forced expiratory volume function
,
hemoglobin a, glycosylated
,
pulmonary function
,
pulmonary function tests
Diabetes Care January 2019, Vol.42, 617-624. doi:https://doi.org/10.2337/dc18-1948
Occurrence of Diabetic Nephropathy After Renal Transplantation Despite Intensive Glycemic Control: An Observational Cohort Study
Maarten Coemans; Elisabet Van Loon; Evelyne Lerut; Pieter Gillard; Ben Sprangers; Aleksandar Senev; Marie-Paule Emonds; Jan Van Keer; Jasper Callemeyn; Liesbeth Daniëls; Jeroen Sichien; Geert Verbeke; Dirk Kuypers; Chantal Mathieu; Maarten Naesens
Topics:
biopsy
,
diabetic nephropathy
,
glycemic control
,
hemoglobin measurement
,
kidney
Diabetes Care February 2019, Vol.42, 625-634. doi:https://doi.org/10.2337/dc18-1936
Cardiovascular and Metabolic Risk
Sex Differences in Cardiovascular Risk Profile From Childhood to Midlife Between Individuals Who Did and Did Not Develop Diabetes at Follow-up: The Bogalusa Heart Study
Tingting Du; Camilo Fernandez; Rupert Barshop; Yajun Guo; Marie Krousel-Wood; Wei Chen; Lu Qi; Emily Harville; Franck Mauvais-Jarvis; Vivian Fonseca; Lydia Bazzano
Topics:
bogalusa heart study
,
child
,
follow-up
,
heart disease risk factors
,
ldl cholesterol lipoproteins
Diabetes Care January 2019, Vol.42, 635-643. doi:https://doi.org/10.2337/dc18-2029
Cardiovascular Risk Factor Burden in People With Incident Type 2 Diabetes in the U.S. Receiving Antidiabetic and Cardioprotective Therapies
Topics:
antidiabetics
,
antihypertensive agents
,
cardiovascular diseases
,
diabetes mellitus, type 2
,
follow-up
Diabetes Care March 2019, Vol.42, 644-650. doi:https://doi.org/10.2337/dc18-1865
Diagnostic Accuracy of a Device for the Automated Detection of Diabetic Retinopathy in a Primary Care Setting
Frank D. Verbraak; Michael D. Abramoff; Gonny C.F. Bausch; Caroline Klaver; Giel Nijpels; Reinier O. Schlingemann; Amber A. van der Heijden
Diabetes Care February 2019, Vol.42, 651-656. doi:https://doi.org/10.2337/dc18-0148
Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study
Barbara H. Braffett; Samuel Dagogo-Jack; Ionut Bebu; William I. Sivitz; Mary Larkin; Orville Kolterman; John M. Lachin; on behalf of the DCCT/EDIC Research Group
Topics:
dcct trial
,
edic trial
,
insulin
,
cardiovascular diseases
,
follow-up
Diabetes Care February 2019, Vol.42, 657-664. doi:https://doi.org/10.2337/dc18-1574
Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation in the United Kingdom
Petros Yiannoullou; Angela Summers; Shu C. Goh; Catherine Fullwood; Hussein Khambalia; Zia Moinuddin; Iestyn M. Shapey; Josephine Naish; Christopher Miller; Titus Augustine; Martin K. Rutter; David van Dellen
Topics:
allografting
,
cardiovascular diseases
,
cardiovascular event
,
heart disease risk factors
,
renal and pancreas transplantation
Diabetes Care February 2019, Vol.42, 665-673. doi:https://doi.org/10.2337/dc18-2111
Glycemic Variability Is a Powerful Independent Predictive Factor of Midterm Major Adverse Cardiac Events in Patients With Diabetes With Acute Coronary Syndrome
Edouard Gerbaud; Romain Darier; Michel Montaudon; Marie-Christine Beauvieux; Christine Coffin-Boutreux; Pierre Coste; Hervé Douard; Alexandre Ouattara; Bogdan Catargi
Topics:
acute coronary syndromes
,
blood glucose
,
cardiac event
,
follow-up
,
glucose
Diabetes Care February 2019, Vol.42, 674-681. doi:https://doi.org/10.2337/dc18-2047
Association of Diabetes and Glycated Hemoglobin With the Risk of Intracerebral Hemorrhage: A Population-Based Cohort Study
Walid Saliba; Ofra Barnett-Griness; Naomi Gronich; Jeremy Molad; Jonathan Naftali; Gad Rennert; Eitan Auriel
Topics:
cerebral hemorrhage
,
hemoglobin
,
hemoglobin a, glycosylated
,
follow-up
Diabetes Care February 2019, Vol.42, 682-688. doi:https://doi.org/10.2337/dc18-2472
Novel Communications in Diabetes
Early Detection of Hypoglycemia in Type 1 Diabetes Using Heart Rate Variability Measured by a Wearable Device
Topics:
diabetes mellitus, type 1
,
early diagnosis
,
hypoglycemia
,
hypoglycemic agents
,
wearable electronic devices
Diabetes Care March 2019, Vol.42, 689-692. doi:https://doi.org/10.2337/dc18-1843
Meta-analysis
Ambulatory Blood Pressure Reduction With SGLT-2 Inhibitors: Dose-Response Meta-analysis and Comparative Evaluation With Low-Dose Hydrochlorothiazide
Topics:
diastolic blood pressure
,
hydrochlorothiazide
,
sodium-glucose transporter 2 inhibitors
,
systole
Diabetes Care March 2019, Vol.42, 693-700. doi:https://doi.org/10.2337/dc18-2207
Errata
Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668—1677
William H. Herman; Qing Pan; Sharon L. Edelstein; Kieren J. Mather; Leigh Perreault; Elizabeth Barrett-Connor; Dana M. Dabelea; Edward Horton; Steven E. Kahn; William C. Knowler; Carlos Lorenzo; Xavier Pi-Sunyer; Elizabeth Venditti; Wen Ye; for the Diabetes Prevention Program Research Group
Topics:
glucose
,
life style
,
metformin
,
obesity
,
overweight
Diabetes Care March 2019, Vol.42, 701. doi:https://doi.org/10.2337/dc19-er04
Erratum. The virtual office visit for women with gestational diabetes mellitus. Diabetes Care 2017;40:e34—e35
Topics:
gestational diabetes
,
office visits
Diabetes Care March 2019, Vol.42, 701. doi:https://doi.org/10.2337/dc19-er04a
Issues and Events
Issues and Events
Topics:
podcasts
,
standard of care
,
health personnel
Diabetes Care March 2019, Vol.42, 702. doi:https://doi.org/10.2337/dc19-ie04
e-Letters
Observations
Retinopathy Outcomes With Empagliflozin Versus Placebo in the EMPA-REG OUTCOME Trial
Silvio E. Inzucchi; Christoph Wanner; Uwe Hehnke; Isabella Zwiener; Stefan Kaspers; Douglas Clark; Jyothis T. George; Bernard Zinman
Topics:
empagliflozin
,
retinal diseases
Diabetes Care January 2019, Vol.42, e53-e55. doi:https://doi.org/10.2337/dc18-1355
Glucose Measurements at Various Time Points During the OGTT and Their Role in Capturing Glucose Response Patterns
Adam Hulman; Róbert Wagner; Dorte Vistisen; Kristine Færch; Beverley Balkau; Melania Manco; Alain Golay; Hans-Ulrich Häring; Martin Heni; Andreas Fritsche; Daniel R. Witte
Topics:
glucose
,
glucose measurement
,
oral glucose tolerance test
Diabetes Care January 2019, Vol.42, e56-e57. doi:https://doi.org/10.2337/dc18-2397
Revalidation of the Hypoglycemia Risk Stratification Tool Using ICD-10 Codes
Andrew J. Karter; E. Margaret Warton; Howard H. Moffet; James D. Ralston; Elbert S. Huang; Donald R. Miller; Kasia J. Lipska
Diabetes Care February 2019, Vol.42, e58-e59. doi:https://doi.org/10.2337/dc18-2154
Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data
Lalantha Leelarathna; Roy W. Beck; Richard M. Bergenstal; Hood Thabit; Roman Hovorka; on behalf of APCam11, AP@home04, and APCam08 Investigators
Topics:
glucose
,
legal guardians
,
sensor
,
hemoglobin a, glycosylated
Diabetes Care February 2019, Vol.42, e60-e61. doi:https://doi.org/10.2337/dc18-2479
Comments and Responses
Comment on Cheng et al. Trends and Disparities in Cardiovascular Mortality Among U.S. Adults With and Without Self-Reported Diabetes, 1988–2015. Diabetes Care 2018;41:2306–2315
Topics:
cardiovascular death
,
health disparity
,
self-report
,
heart disease risk factors
,
blood glucose
Diabetes Care March 2019, Vol.42, e62. doi:https://doi.org/10.2337/dc18-2175
Response to Comment on Cheng et al. Trends and Disparities in Cardiovascular Mortality Among U.S. Adults With and Without Self-Reported Diabetes, 1988–2015. Diabetes Care 2018;41:2306–2315
Topics:
cardiovascular death
,
health disparity
,
self-report
Diabetes Care March 2019, Vol.42, e63. doi:https://doi.org/10.2337/dci18-0057
Comment on Lacy et al. Long-term Glycemic Control and Dementia Risk in Type 1 Diabetes. Diabetes Care 2018;41:2339–2345
Topics:
dementia
,
diabetes mellitus, type 1
,
glycemic control
Diabetes Care March 2019, Vol.42, e68. doi:https://doi.org/10.2337/dc18-2467
Response to Comment on Lacy et al. Long-term Glycemic Control and Dementia Risk in Type 1 Diabetes. Diabetes Care 2018;41:2339–2345
Mary E. Lacy; Paola Gilsanz; Andrew J. Karter; Charles P. Quesenberry; Mark J. Pletcher; Rachel A. Whitmer
Topics:
dementia
,
diabetes mellitus, type 1
,
glycemic control
Diabetes Care March 2019, Vol.42, e69. doi:https://doi.org/10.2337/dci18-0065