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March 2021
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Cover: Summer meadow, watercolor painting. Credit: Pobytov. For more information, please visit istockphoto.com.
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
Presidential Address
50 Years of Behavioral Science in Diabetes: A 2020 Vision of the Future
Diabetes Care February 2021, Vol.44, 633-640. doi:https://doi.org/10.2337/dci20-0058
Perspectives in Care
Clinical Translation of Cardiovascular Outcome Trials in Type 2 Diabetes: Is There More or Is There Less Than Meets the Eye?
Diabetes Care February 2021, Vol.44, 641-646. doi:https://doi.org/10.2337/dc20-0913
Metformin Benefits: Another Example for Alternative Energy Substrate Mechanism?
Diabetes Care February 2021, Vol.44, 647-654. doi:https://doi.org/10.2337/dc20-1964
Clinical Care / Education / Nutrition / Psychosocial Research
Specific Dimensions of Depression Have Different Associations With Cognitive Decline in Older Adults With Type 2 Diabetes
Laili Soleimani; Ramit Ravona-Springer; Hung-Mo Lin; Xiaoyu Liu; Mary Sano; Anthony Heymann; Michal Schnaider Beeri
Diabetes Care January 2021, Vol.44, 655-662. doi:https://doi.org/10.2337/dc20-2031
Changes in Plant-Based Diet Indices and Subsequent Risk of Type 2 Diabetes in Women and Men: Three U.S. Prospective Cohorts
Zhangling Chen; Jean-Philippe Drouin-Chartier; Yanping Li; Megu Y. Baden; JoAnn E. Manson; Walter C. Willett; Trudy Voortman; Frank B. Hu; Shilpa N. Bhupathiraju
Diabetes Care January 2021, Vol.44, 663-671. doi:https://doi.org/10.2337/dc20-1636
Association of Oily and Nonoily Fish Consumption and Fish Oil Supplements With Incident Type 2 Diabetes: A Large Population-Based Prospective Study
Guo-Chong Chen; Rhonda Arthur; Li-Qiang Qin; Li-Hua Chen; Zhendong Mei; Yan Zheng; Yang Li; Tao Wang; Thomas E. Rohan; Qibin Qi
Diabetes Care January 2021, Vol.44, 672-680. doi:https://doi.org/10.2337/dc20-2328
Novel Biochemical Markers of Glycemia to Predict Pregnancy Outcomes in Women With Type 1 Diabetes
Claire L. Meek; Diana Tundidor; Denice S. Feig; Jennifer M. Yamamoto; Eleanor M. Scott; Diane D. Ma; Jose A. Halperin; Helen R. Murphy; Rosa Corcoy; on behalf of the CONCEPTT Collaborative Group
Diabetes Care February 2021, Vol.44, 681-689. doi:https://doi.org/10.2337/dc20-2360
Not Only Diabetes but Also Prediabetes Leads to Functional Decline and Disability in Older Adults
Diabetes Care January 2021, Vol.44, 690-698. doi:https://doi.org/10.2337/dc20-2232
Epidemiology / Health Services Research
Thirty-Year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes
Diabetes Care January 2021, Vol.44, 699-706. doi:https://doi.org/10.2337/dc20-2304
Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women
Qi Jin; Ni Shi; Desmond Aroke; Dong Hoon Lee; Joshua J. Joseph; Macarius Donneyong; Darwin L. Conwell; Phil A. Hart; Xuehong Zhang; Steven K. Clinton; Zobeida Cruz-Monserrate; Theodore M. Brasky; Rebecca Jackson; Lesley F. Tinker; Simin Liu; Lawrence S. Phillips; Aladdin H. Shadyab; Rami Nassir; Wei Bao; Fred K. Tabung
Diabetes Care January 2021, Vol.44, 707-714. doi:https://doi.org/10.2337/dc20-2216
Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
Kirthi Menon; Barbora de Courten; Danny Liew; Zanfina Ademi; Alice J. Owen; Dianna J. Magliano; Ella Zomer
Diabetes Care January 2021, Vol.44, 715-721. doi:https://doi.org/10.2337/dc20-1429
Temporal Trends in Incident Hospitalization for Diabetes-Related Foot Ulcer in Type 2 Diabetes: The Fremantle Diabetes Study
Diabetes Care January 2021, Vol.44, 722-730. doi:https://doi.org/10.2337/dc20-1743
Social Deprivation and Incident Diabetes-Related Foot Disease in Patients With Type 2 Diabetes: A Population-Based Cohort Study
Jenny Riley; Christina Antza; Punith Kempegowda; Anuradhaa Subramanian; Joht Singh Chandan; Krishna Gokhale; Neil Thomas; Christopher Sainsbury; Abd A. Tahrani; Krishnarajah Nirantharakumar
Diabetes Care January 2021, Vol.44, 731-739. doi:https://doi.org/10.2337/dc20-1027
Trajectories of Childhood Adversity and Type 1 Diabetes: A Nationwide Study of One Million Children
Jessica Bengtsson; Andreas Rieckmann; Bendix Carstensen; Jannet Svensson; Marit E. Jørgensen; Naja H. Rod
Diabetes Care February 2021, Vol.44, 740-747. doi:https://doi.org/10.2337/dc20-1130
Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy
Charles C. Wykoff; Rahul N. Khurana; Quan Dong Nguyen; Scott P. Kelly; Flora Lum; Rebecca Hall; Ibrahim M. Abbass; Anna M. Abolian; Ivaylo Stoilov; Tu My To; Vincent Garmo
Diabetes Care January 2021, Vol.44, 748-756. doi:https://doi.org/10.2337/dc20-0413
Prediabetes, Diabetes, and the Risk of All-Cause and Cause-Specific Mortality in a Japanese Working Population: Japan Epidemiology Collaboration on Occupational Health Study
Zobida Islam; Shamima Akter; Yosuke Inoue; Huan Hu; Keisuke Kuwahara; Tohru Nakagawa; Toru Honda; Shuichiro Yamamoto; Hiroko Okazaki; Toshiaki Miyamoto; Takayuki Ogasawara; Naoko Sasaki; Akihiko Uehara; Makoto Yamamoto; Takeshi Kochi; Masafumi Eguchi; Taiki Shirasaka; Makiko Shimizu; Satsue Nagahama; Ai Hori; Teppei Imai; Akiko Nishihara; Kentaro Tomita; Tomofumi Sone; Maki Konishi; Isamu Kabe; Tetsuya Mizoue; Seitaro Dohi; for the Japan Epidemiology Collaboration on Occupational Health Study Group
Diabetes Care January 2021, Vol.44, 757-764. doi:https://doi.org/10.2337/dc20-1213
Emerging Therapies: Drugs and Regimens
Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
Juan P. Frias; Enzo Bonora; Luis Nevarez Ruiz; Ying G. Li; Zhuoxin Yu; Zvonko Milicevic; Raleigh Malik; M. Angelyn Bethel; David A. Cox
Diabetes Care January 2021, Vol.44, 765-773. doi:https://doi.org/10.2337/dc20-1473
Durable Effects of iGlarLixi Up to 52 Weeks in Type 2 Diabetes: The LixiLan-G Extension Study
Lawrence Blonde; Julio Rosenstock; Juan Frias; Andreas L. Birkenfeld; Elisabeth Niemoeller; Elisabeth Souhami; Chen Ji; Stefano Del Prato; Vanita R. Aroda
Diabetes Care January 2021, Vol.44, 774-780. doi:https://doi.org/10.2337/dc20-2023
Emerging Technologies: Data Systems and Devices
The SEE Study: Safety, Efficacy, and Equity of Implementing Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth
Risa M. Wolf; T.Y. Alvin Liu; Chrystal Thomas; Laura Prichett; Ingrid Zimmer‐Galler; Kerry Smith; Michael D. Abramoff; Roomasa Channa
Diabetes Care January 2021, Vol.44, 781-787. doi:https://doi.org/10.2337/dc20-1671
Pathophysiology / Complications
Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
Eleni Rebelos; Marco Bucci; Tomi Karjalainen; Vesa Oikonen; Alessandra Bertoldo; Jarna C. Hannukainen; Kirsi A. Virtanen; Aino Latva-Rasku; Jussi Hirvonen; Ilkka Heinonen; Riitta Parkkola; Markku Laakso; Ele Ferrannini; Patricia Iozzo; Lauri Nummenmaa; Pirjo Nuutila
Diabetes Care January 2021, Vol.44, 788-794. doi:https://doi.org/10.2337/dc20-1549
Cardiovascular and Metabolic Risk
Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes
Kalie L. Tommerdahl; Karl Baumgartner; Michal Schäfer; Petter Bjornstad; Isabella Melena; Shannon Hegemann; Amy D. Baumgartner; Laura Pyle; Melanie Cree-Green; Uyen Truong; Lorna Browne; Judith G. Regensteiner; Jane E.B. Reusch; Kristen J. Nadeau
Diabetes Care January 2021, Vol.44, 795-803. doi:https://doi.org/10.2337/dc20-1879
Carbamylated HDL and Mortality Outcomes in Type 2 Diabetes
Diabetes Care January 2021, Vol.44, 804-809. doi:https://doi.org/10.2337/dc20-2186
Serum Galectin-3 and Subsequent Risk of Coronary Heart Disease in Subjects With Childhood-Onset Type 1 Diabetes: A Cohort Study
Maryam Saeed; German Tapia; Inger Ariansen; Lars C. Stene; Ingebjørg Seljeflot; Grethe S. Tell; Torild Skrivarhaug; Geir Joner
Diabetes Care January 2021, Vol.44, 810-816. doi:https://doi.org/10.2337/dc20-1712
OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function
Silva A. Arslanian; Laure El ghormli; Joon Young Kim; Ashley H. Tjaden; Elena Barengolts; Sonia Caprio; Tamara S. Hannon; Kieren J. Mather; Kristen J. Nadeau; Kristina M. Utzschneider; Steven E. Kahn; RISE Consortium
Diabetes Care January 2021, Vol.44, 817-825. doi:https://doi.org/10.2337/dc20-2134
Comparative Effectiveness and Safety of Sodium–Glucose Cotransporter 2 Inhibitors Versus Glucagon-Like Peptide 1 Receptor Agonists in Older Adults
Elisabetta Patorno; Ajinkya Pawar; Lily G. Bessette; Dae H. Kim; Chintan Dave; Robert J. Glynn; Medha N. Munshi; Sebastian Schneeweiss; Deborah J. Wexler; Seoyoung C. Kim
Diabetes Care February 2021, Vol.44, 826-835. doi:https://doi.org/10.2337/dc20-1464
Novel Communications in Diabetes
Fully Closed Loop Glucose Control With a Bihormonal Artificial Pancreas in Adults With Type 1 Diabetes: An Outpatient, Randomized, Crossover Trial
Diabetes Care January 2021, Vol.44, 836-838. doi:https://doi.org/10.2337/dc20-2106
Stay-at-Home Orders During the COVID-19 Pandemic, an Opportunity to Improve Glucose Control Through Behavioral Changes in Type 1 Diabetes
Louis Potier; Boris Hansel; Etienne Larger; Jean-François Gautier; Daphné Carreira; Rachel Assemien; Olivier Lantieri; Jean-Pierre Riveline; Ronan Roussel
Diabetes Care December 2020, Vol.44, 839-843. doi:https://doi.org/10.2337/dc20-2019
Diabeloop DBLG1 Closed-Loop System Enables Patients With Type 1 Diabetes to Significantly Improve Their Glycemic Control in Real-Life Situations Without Serious Adverse Events: 6-Month Follow-up
Coralie Amadou; Sylvia Franc; Pierre-Yves Benhamou; Sandrine Lablanche; Erik Huneker; Guillaume Charpentier; Alfred Penfornis; on behalf of the Diabeloop Consortium
Diabetes Care January 2021, Vol.44, 844-846. doi:https://doi.org/10.2337/dc20-1809
Continuous Glucose Monitoring in the Intensive Care Unit During the COVID-19 Pandemic
Shivani Agarwal; Justin Mathew; Georgia M. Davis; Alethea Shephardson; Ann Levine; Rita Louard; Agustina Urrutia; Citlalli Perez-Guzman; Guillermo E. Umpierrez; Limin Peng; Francisco J. Pasquel
Diabetes Care December 2020, Vol.44, 847-849. doi:https://doi.org/10.2337/dc20-2219
The Effect of BMI and Type 2 Diabetes on Socioeconomic Status: A Two-Sample Multivariable Mendelian Randomization Study
Diabetes Care January 2021, Vol.44, 850-852. doi:https://doi.org/10.2337/dc20-1721
Issues and Events
e-Letters
Observations
DPP-4 Inhibitors and Respiratory Infection: A Systematic Review and Meta-analysis of the Cardiovascular Outcomes Trials
Guillaume Grenet; Samia Mekhaldi; Sabine Mainbourg; Marine Auffret; Catherine Cornu; Jean-Luc Cracowski; François Gueyffier; Jean-Christophe Lega; Michel Cucherat
Diabetes Care January 2021, Vol.44, e36-e37. doi:https://doi.org/10.2337/dc20-2018
Citizenship Status and Prevalence of Diagnosed and Undiagnosed Hypertension and Diabetes Among Adults in the U.S., 2011–2016
Diabetes Care January 2021, Vol.44, e38-e39. doi:https://doi.org/10.2337/dc20-2453
Severe Hypoglycemia and Risk of Atherosclerotic Cardiovascular Disease in Patients With Diabetes
Diabetes Care January 2021, Vol.44, e40-e41. doi:https://doi.org/10.2337/dc20-2798
Effects of Lifestyle Intervention of Maternal Gestational Diabetes Mellitus on Offspring Growth Pattern Before Two Years of Age
Jing Li; Jinnan Liu; Cuiping Zhang; Gongshu Liu; Junhong Leng; Leishen Wang; Weiqin Li; Zhijie Yu; Gang Hu; Juliana C.N. Chan; Xilin Yang
Diabetes Care February 2021, Vol.44, e42-e44. doi:https://doi.org/10.2337/dc20-2750
Changes in Cardiovascular Biomarkers Associated With the Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitor Ertugliflozin in Patients With Chronic Kidney Disease and Type 2 Diabetes
Patrick R. Lawler; Hongyan Liu; Claudia Frankfurter; Leif Erik Lovblom; Yuliya Lytvyn; Dylan Burger; Kevin D. Burns; Davor Brinc; David Z.I. Cherney
Diabetes Care January 2021, Vol.44, e45-e47. doi:https://doi.org/10.2337/dc20-2265
Comparison of Diagnostic Accuracy for Lower-Extremity Amputation Codes During the ICD-9 and ICD-10 Eras in a High-Risk Population of Patients With Diabetes
Alyson J. Littman; Andrew K. Timmons; Kathryn P. Moore; Chin-Lin Tseng; Gregory Landry; Jeffrey M. Robbins; Anna Korpak; Edward J. Boyko
Diabetes Care January 2021, Vol.44, e48-e49. doi:https://doi.org/10.2337/dc20-2452
Continuous Glucose Monitoring in the Operating Room and Cardiac Intensive Care Unit
M. Citlalli Perez-Guzman; Elizabeth Duggan; Seid Gibanica; Saumeth Cardona; Andrea Corujo-Rodriguez; Abimbola Faloye; Michael Halkos; Guillermo E. Umpierrez; Limin Peng; Georgia M. Davis; Francisco J. Pasquel
Diabetes Care January 2021, Vol.44, e50-e52. doi:https://doi.org/10.2337/dc20-2386
Vertebral Ischemic Necrosis in Diabetic Lumbosacral Radiculoplexus Neuropathy
Diabetes Care January 2021, Vol.44, e53-e54. doi:https://doi.org/10.2337/dc20-2787
Early Worsening of Diabetic Nephropathy in Type 2 Diabetes After Rapid Improvement in Chronic Severe Hyperglycemia
Diabetes Care January 2021, Vol.44, e55-e56. doi:https://doi.org/10.2337/dc20-2646
Degree of Cardiometabolic Risk Factor Normalization in Individuals Receiving Bariatric Surgery: Evidence From NHANES 2015–2018
Diabetes Care January 2021, Vol.44, e57-e58. doi:https://doi.org/10.2337/dc20-2748
Comments and Responses
Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
Diabetes Care February 2021, Vol.44, e59-e60. doi:https://doi.org/10.2337/dc20-2575
Response to Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
Roselle A. Herring; Fariba Shojaee-Moradie; Robert Garesse; Mary Stevenage; Nicola Jackson; Barbara A. Fielding; Agampodi Mendis; Sigurd Johnsen; A. Margot Umpleby; Melanie Davies; David L. Russell-Jones
Diabetes Care February 2021, Vol.44, e61. doi:https://doi.org/10.2337/dci20-0072
