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October 2022
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ISSN 0149-5992
EISSN 1935-5548
In this Issue
In This Issue
In This Issue of Diabetes Care
Diabetes Care September 2022, Vol.45, 2187-2188. doi:https://doi.org/10.2337/dc22-ti10
Perspectives in Care
Innovative Designs and Logistical Considerations for Expedited Clinical Development of Combination Disease-Modifying Treatments for Type 1 Diabetes
Randy L. Anderson; Linda A. DiMeglio; Adrian P. Mander; Colin M. Dayan; Peter S. Linsley; Kevan C. Herold; Marjana Marinac; Simi T. Ahmed
Diabetes Care September 2022, Vol.45, 2189-2201. doi:https://doi.org/10.2337/dc22-0308
Commentaries
To Correct or Not to Correct: Lost in Inpatient Translation
Diabetes Care September 2022, Vol.45, 2202-2203. doi:https://doi.org/10.2337/dci22-0023
A New Bar for Pharmacologic Weight Loss: Type 2 Diabetes Prevention
Diabetes Care September 2022, Vol.45, 2204-2206. doi:https://doi.org/10.2337/dci22-0019
Profiles in Progress
Professor Juliana Chung Ngor Chan: Tireless Trailblazer for Diabetes Research, Care, and Education in Asia
Diabetes Care September 2022, Vol.45, 2207-2216. doi:https://doi.org/10.2337/dci22-0016
Clinical Care/Education/Nutrition/Psychosocial Research
Efficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study
Priyathama Vellanki; Saumeth Cardona; Rodolfo J. Galindo; Maria A. Urrutia; Francisco J. Pasquel; Georgia M. Davis; Maya Fayfman; Alexandra Migdal; Limin Peng; Guillermo E. Umpierrez
Diabetes Care June 2022, Vol.45, 2217-2223. doi:https://doi.org/10.2337/dc21-1606
Targeting Technology in Underserved Adults With Type 1 Diabetes: Effect of Diabetes Practice Transformations on Improving Equity in CGM Prescribing Behaviors
Diabetes Care September 2022, Vol.45, 2231-2237. doi:https://doi.org/10.2337/dc22-0555
First STEPS: Primary Outcomes of a Randomized, Stepped-Care Behavioral Clinical Trial for Parents of Young Children With New-Onset Type 1 Diabetes
Marisa E. Hilliard; Carrie Tully; Maureen Monaghan; Tom Hildebrandt; Christine H. Wang; John R. Barber; Lauren Clary; Katherine Gallagher; Wendy Levy; Fran Cogen; Celia Henderson; Lefkothea Karaviti; Randi Streisand
Diabetes Care August 2022, Vol.45, 2238-2246. doi:https://doi.org/10.2337/dc21-2704
Epidemiology/Health Services Research
Thirty-Year Time Trends in Diabetic Retinopathy and Macular Edema in Youth With Type 1 Diabetes
Digby W. Allen; Gerald Liew; Yoon Hi Cho; Alison Pryke; Janine Cusumano; Stephen Hing; Albert K. Chan; Maria E. Craig; Kim C. Donaghue
Diabetes Care May 2022, Vol.45, 2247-2254. doi:https://doi.org/10.2337/dc21-1652
Effect of State-Led Delivery System and Payment Reforms on Population-Level Detection and Management of Diabetes
Diabetes Care August 2022, Vol.45, 2255-2263. doi:https://doi.org/10.2337/dc21-2425
The Transition From a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk
Heba M. Ismail; David Cuthbertson; Stephen E. Gitelman; Jay S. Skyler; Andrea K. Steck; Henry Rodriguez; Mark Atkinson; Brandon M. Nathan; Maria J. Redondo; Kevan C. Herold; Carmella Evans-Molina; Linda A. DiMeglio; Jay Sosenko; on behalf of DPT-1 and TrialNet Study Groups
Diabetes Care August 2022, Vol.45, 2264-2270. doi:https://doi.org/10.2337/dc22-0167
Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study
Jeffrey P. Krischer; on behalf of the TEDDY Study Group; Xiang Liu; on behalf of the TEDDY Study Group; Åke Lernmark; on behalf of the TEDDY Study Group; William A. Hagopian; on behalf of the TEDDY Study Group; Marian J. Rewers; on behalf of the TEDDY Study Group; Jin-Xiong She; on behalf of the TEDDY Study Group; Jorma Toppari; on behalf of the TEDDY Study Group; Anette-G. Ziegler; on behalf of the TEDDY Study Group; Beena Akolkar; on behalf of the TEDDY Study Group; TEDDY Study Group
Diabetes Care September 2022, Vol.45, 2271-2281. doi:https://doi.org/10.2337/dc21-2612
Health Beliefs Associated With Metformin Use Among Insured Adults With Prediabetes
Diabetes Care August 2022, Vol.45, 2282-2288. doi:https://doi.org/10.2337/dc21-2316
Incretin-Based Drugs and the Risk of Acute Liver Injury Among Patients With Type 2 Diabetes
Diabetes Care July 2022, Vol.45, 2289-2298. doi:https://doi.org/10.2337/dc22-0712
Trends in Prescribing Preferences for Antidiabetic Medications Among Patients With Type 2 Diabetes in the U.K. With and Without Chronic Kidney Disease, 2006–2020
Diabetes Care August 2022, Vol.45, 2316-2325. doi:https://doi.org/10.2337/dc22-0224
Range of Risk Factor Levels, Risk Control, and Temporal Trends for Nephropathy and End-stage Kidney Disease in Patients With Type 1 and Type 2 Diabetes
Janita Halminen; Naveed Sattar; Araz Rawshani; Björn Eliasson; Katarina Eeg-Olofsson; Deepak L. Bhatt; Aidin Rawshani
Diabetes Care August 2022, Vol.45, 2326-2335. doi:https://doi.org/10.2337/dc22-0926
Racial Disparities in Health Care With Timing to Amputation Following Diabetic Foot Ulcer
Diabetes Care September 2022, Vol.45, 2336-2341. doi:https://doi.org/10.2337/dc21-2693
Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests
Kendra Vehik; for the TrialNet Study Group and TEDDY Study Group; David Boulware; for the TrialNet Study Group and TEDDY Study Group; Michael Killian; for the TrialNet Study Group and TEDDY Study Group; Marian Rewers; for the TrialNet Study Group and TEDDY Study Group; Richard McIndoe; for the TrialNet Study Group and TEDDY Study Group; Jorma Toppari; for the TrialNet Study Group and TEDDY Study Group; Åke Lernmark; for the TrialNet Study Group and TEDDY Study Group; Beena Akolkar; for the TrialNet Study Group and TEDDY Study Group; Anette-G. Ziegler; for the TrialNet Study Group and TEDDY Study Group; Henry Rodriguez; for the TrialNet Study Group and TEDDY Study Group; Desmond A. Schatz; for the TrialNet Study Group and TEDDY Study Group; Jeffrey P. Krischer; for the TrialNet Study Group and TEDDY Study Group; William Hagopian; for the TrialNet Study Group and TEDDY Study Group; The TEDDY Study Group
Diabetes Care September 2022, Vol.45, 2342-2349. doi:https://doi.org/10.2337/dc22-0828
Emerging Therapies: Drugs and Regimens
Dapagliflozin and Prevention of Kidney Disease Among Patients With Type 2 Diabetes: Post Hoc Analyses From the DECLARE-TIMI 58 Trial
Ofri Mosenzon; Itamar Raz; Stephen D. Wiviott; Meir Schechter; Erica L. Goodrich; Ilan Yanuv; Aliza Rozenberg; Sabina A. Murphy; Thomas A. Zelniker; Anna Maria Langkilde; Ingrid A.M. Gause-Nilsson; Martin Fredriksson; Peter A. Johansson; John P.H. Wilding; Darren K. McGuire; Deepak L. Bhatt; Lawrence A. Leiter; Avivit Cahn; Jamie P. Dwyer; Hiddo J.L. Heerspink; Marc S. Sabatine
Diabetes Care August 2022, Vol.45, 2350-2359. doi:https://doi.org/10.2337/dc22-0382
Emerging Technologies: Data Systems and Devices
Glycemic Variability Patterns Strongly Correlate With Partial Remission Status in Children With Newly Diagnosed Type 1 Diabetes
Olivier G. Pollé; Antoine Delfosse; Manon Martin; Jacques Louis; Inge Gies; Marieke den Brinker; Nicole Seret; Marie-Christine Lebrethon; Thierry Mouraux; Laurent Gatto; Philippe A. Lysy; on behalf of the DIATAG Working Group
Diabetes Care August 2022, Vol.45, 2360-2368. doi:https://doi.org/10.2337/dc21-2543
Continuous Glucose Monitoring–Guided Insulin Administration in Hospitalized Patients With Diabetes: A Randomized Clinical Trial
Elias K. Spanakis; Agustina Urrutia; Rodolfo J. Galindo; Priyathama Vellanki; Alexandra L. Migdal; Georgia Davis; Maya Fayfman; Thaer Idrees; Francisco J. Pasquel; Walkiria Zamudio Coronado; Bonnie Albury; Emmenlin Moreno; Lakshmi G. Singh; Isabel Marcano; Sergio Lizama; Chikara Gothong; Kashif Munir; Catalina Chesney; Rebecca Maguire; William H. Scott; M. Citlalli Perez-Guzman; Saumeth Cardona; Limin Peng; Guillermo E. Umpierrez
Diabetes Care August 2022, Vol.45, 2369-2375. doi:https://doi.org/10.2337/dc22-0716
Pathophysiology/Complications
The Association of Measures of Cardiovascular Autonomic Function, Heart Rate, and Orthostatic Hypotension With Incident Glucose Disorders: The Cardiovascular Health Study
Joshua I. Barzilay; William Tressel; Mary L. Biggs; Phyllis K. Stein; Jorge R. Kizer; Sanyog G. Shitole; Yakubu Bene-Alhasan; Kenneth J. Mukamal
Diabetes Care August 2022, Vol.45, 2376-2382. doi:https://doi.org/10.2337/dc22-0553
Optimal Frequency of Retinopathy Screening in Adolescents With Type 1 Diabetes: Markov Modeling Approach Based on 30 Years of Data
Andrzej S. Januszewski; Vallimayil Velayutham; Paul Z. Benitez-Aguirre; Maria E. Craig; Janine Cusumano; Alison Pryke; Stephen Hing; Gerald Liew; Yoon Hi Cho; Emily Y. Chew; Alicia J. Jenkins; Kim C. Donaghue
Diabetes Care August 2022, Vol.45, 2383-2390. doi:https://doi.org/10.2337/dc22-0071
Cardiac Autonomic Nerve Dysfunction Predicts Incident Retinopathy and Early Kidney Dysfunction in Adolescents With Type 1 Diabetes
Diabetes Care August 2022, Vol.45, 2391-2395. doi:https://doi.org/10.2337/dc22-0349
Cardiovascular and Metabolic Risk
Changes in Glucose Metabolism and Glycemic Status With Once-Weekly Subcutaneous Semaglutide 2.4 mg Among Participants With Prediabetes in the STEP Program
Leigh Perreault; Melanie Davies; Juan P. Frias; Peter Nørkjaer Laursen; Ildiko Lingvay; Sriram Machineni; Anette Varbo; John P.H. Wilding; Signe Olrik Rytter Wallenstein; Carel W. le Roux
Diabetes Care June 2022, Vol.45, 2396-2405. doi:https://doi.org/10.2337/dc21-1785
COVID-19 Exacerbates Insulin Resistance During Diabetic Ketoacidosis in Pediatric Patients With Type 1 Diabetes
Elizabeth S. Keiner; James C. Slaughter; Karishma A. Datye; Alan D. Cherrington; Daniel J. Moore; Justin M. Gregory
Diabetes Care August 2022, Vol.45, 2406-2411. doi:https://doi.org/10.2337/dc22-0396
Use of the Steno T1 Risk Engine Identifies Preclinical Atherosclerosis Better Than Use of ESC/EASD-2019 in Adult Subjects With Type 1 Diabetes at High Risk
Tonet Serés-Noriega; Marga Giménez; Verónica Perea; Laura Boswell; Clara Viñals; Jesús Blanco; Irene Vinagre; Adriana Pané; Enric Esmatjes; Ignacio Conget; Antonio J. Amor
Diabetes Care August 2022, Vol.45, 2412-2421. doi:https://doi.org/10.2337/dc22-0118
Associations of New-Onset Atrial Fibrillation With Risks of Cardiovascular Disease, Chronic Kidney Disease, and Mortality Among Patients With Type 2 Diabetes
Tingting Geng; Yi Wang; Qi Lu; Yan-Bo Zhang; Jun-Xiang Chen; Yan-Feng Zhou; Zhenzhen Wan; Kunquan Guo; Kun Yang; Liegang Liu; Gang Liu; An Pan
Diabetes Care August 2022, Vol.45, 2422-2429. doi:https://doi.org/10.2337/dc22-0717
Measurement of Serum N-Glycans in the Assessment of Early Vascular Aging (Arterial Stiffness) in Adults With Type 1 Diabetes
Gemma Llauradó; Núria Amigó; Rocío Fuertes-Martín; Ana Romero; Albert Cano; Lara Albert; Olga Giménez-Palop; Eugenio Berlanga; Sonia Fernández-Veledo; Xavier Correig; Joan Vendrell; José-Miguel González-Clemente
Diabetes Care August 2022, Vol.45, 2430-2438. doi:https://doi.org/10.2337/dc22-0331
The Fast-Glycator Phenotype, Skin Advanced Glycation End Products, and Complication Burden Among People With Type 1 Diabetes
Diabetes Care August 2022, Vol.45, 2439-2444. doi:https://doi.org/10.2337/dc22-0980
Novel Communications in Diabetes
Association of Estimated Time-in-Range Capillary Glucose Levels Versus HbA1c With Progression of Microvascular Complications in the Diabetes Control and Complications Trial
John M. Lachin; Ionut Bebu; Xiaoyu Gao; David M. Nathan; Bernard Zinman; the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
Diabetes Care August 2022, Vol.45, 2445-2448. doi:https://doi.org/10.2337/dc21-2298
Noninvasive Fibrosis Screening in Fatty Liver Disease Among Vulnerable Populations: Impact of Diabetes and Obesity on FIB-4 Score Accuracy
Diabetes Care August 2022, Vol.45, 2449-2451. doi:https://doi.org/10.2337/dc22-0556
Impact of a Novel Diabetes Prevention Intervention for Early Slow Weight Loss Responders Among Adults With Prediabetes: An Adaptive Trial
Diabetes Care September 2022, Vol.45, 2452-2455. doi:https://doi.org/10.2337/dc22-0824
Symptoms of Anxiety and Depression Are Independently Associated With Impaired Awareness of Hypoglycemia in Type 1 Diabetes
Beatrice A. Pieri; Gabriella A.I. Bergin-Cartwright; Anna Simpson; Julian Collins; Anna Reid; Janaka Karalliedde; Anna Brackenridge; Matthew Hotopf; Sufyan Hussain
Diabetes Care August 2022, Vol.45, 2456-2460. doi:https://doi.org/10.2337/dc21-2482
Cardiovascular Autonomic Neuropathy Is Associated With Increased Glucose Variability in People With Type 1 Diabetes
Sara H. Naaman; Hatice I. Mizrak; Nanna Lind; Jens C. Laursen; Huda Kufaishi; Marie M.B. Christensen; Ajenthen G. Ranjan; Kirsten Nørgaard; Christian S. Hansen
Diabetes Care August 2022, Vol.45, 2461-2465. doi:https://doi.org/10.2337/dc22-0117
Meta-analysis
Systematic Review and Network Meta-analysis of Neurostimulation for Painful Diabetic Neuropathy
Rui V. Duarte; Sarah Nevitt; Sue Copley; Michelle Maden; Cecile C. de Vos; Rod S. Taylor; Sam Eldabe
Diabetes Care September 2022, Vol.45, 2466-2475. doi:https://doi.org/10.2337/dc22-0932
Erratum
Erratum. Patients With Type 2 Diabetes Have an Increased Demand for Pacemaker Treatment: A Comparison With Age- and Sex-Matched Control Subjects From the General Population. Diabetes Care 2020;44:2853–2858
Elina Rautio; Fredrik Gadler; Soffia Gudbjörnsdottir; Stefan Franzén; Lars Rydén; Ann-Marie Svensson; Linda G. Mellbin
Diabetes Care August 2022, Vol.45, 2476. doi:https://doi.org/10.2337/dc22-er10
Issues and Events
e-Letters – Observations
Concomitant Use of Sulfonylureas and Warfarin and the Risk of Severe Hypoglycemia: Population-Based Cohort Study
Diabetes Care August 2022, Vol.45, e131-e133. doi:https://doi.org/10.2337/dc21-2383
Effect of Insulin Delivery Strategies on Glycemic Control and Nursing Exposure in Critically Ill Patients With COVID-19: An Observational Cohort Study
Diabetes Care August 2022, Vol.45, e134-e135. doi:https://doi.org/10.2337/dc21-2602
Can the Artificial Intelligence System for Urine Microalbuminuria Detection Monitor the Progression of Diabetic Kidney Disease in the Clinical Laboratory?
Xiaozhe Lin; Yingxiu Xiao; Yaqiong Tian; Bizhen Cheng; Xiaoyang Jiao; Xinran Yang; Yongni Wang; Wenjing Xiong; Wenyan Guo; Qingyu Wu; Qiaoxin Zhang
Diabetes Care August 2022, Vol.45, e136-e138. doi:https://doi.org/10.2337/dc22-0966
Painful Diabetic Neuropathy: Myofascial Pain Makes the Difference
Fabiola Escolano-Lozano; Felix Buehling-Schindowski; Heidrun H. Krämer; Frank Birklein; Christian Geber
Diabetes Care August 2022, Vol.45, e139-e140. doi:https://doi.org/10.2337/dc22-1023
Acute and Chronic Diabetes-Related Complications Among Patients With Diabetes Receiving Care in Community Health Centers
Irina Chamine; Jun Hwang; Steele Valenzuela; Miguel Marino; Annie E. Larson; Joanna Georgescu; Michaella Latkovic-Taber; Heather Angier; Jennifer E. DeVoe; Nathalie Huguet
Diabetes Care August 2022, Vol.45, e141-e143. doi:https://doi.org/10.2337/dc22-0420
The At-Risk Diabetic Foot: Time to Focus on Prevention
Diabetes Care August 2022, Vol.45, e144-e145. doi:https://doi.org/10.2337/dc22-1111
Dulaglutide and a Composite Outcome Reflecting Atherosclerosis in the REWIND Trial: A Post Hoc Analysis
Giulia Ferrannini; Linda G. Mellbin; Faith Kirabo; Chinthanie Ramasundarahettige; Hertzel C. Gerstein; Lars Rydén
Diabetes Care August 2022, Vol.45, e146-e147. doi:https://doi.org/10.2337/dc22-0903
Activation of the Tubulo-Glomerular Feedback by SGLT2 Inhibitors in Patients With Type 2 Diabetes and Advanced Chronic Kidney Disease: Toward the End of a Myth?
Diabetes Care August 2022, Vol.45, e148-e149. doi:https://doi.org/10.2337/dc22-0921
e-Letters – Comments and Responses
Response to Comment on Mone et al. Empagliflozin Improves Cognitive Impairment in Frail Older Adults With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction. Diabetes Care 2022;45:1247–1251
Gaetano Santulli; Salvatore Frullone; Maria Morgante; Gaetano Macina; Antonella Pansini; Jessica Gambardella; Angela Lombardi; Pasquale Mone
Diabetes Care September 2022, Vol.45, e151-e152. doi:https://doi.org/10.2337/dci22-0025
