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Alisa K. Manning
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Journal Articles

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts

Free
Amber M. Luckett, Richard A. Oram, Aaron J. Deutsch, Hector I. Ortega, Diane P. Fraser, Kaavya Ashok, Alisa K. Manning, Josep M. Mercader, Manuel A. Rivas, Miriam S. Udler, Michael N. Weedon, Anna L. Gloyn, Seth A. Sharp
Journal: Diabetes Care
Diabetes Care 2025;48(6):e81–e83
https://doi.org/10.2337/dc25-0142
Published: 23 April 2025
View articletitled, Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts
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Journal Articles

Genome-Wide Polygenic Risk Score Predicts Incident Type 2 Diabetes in Women With History of Gestational Diabetes

Available to Purchase
Jaewon Choi, Hyunsuk Lee, Alan Kuang, Alicia Huerta-Chagoya, Denise M. Scholtens, Daeho Choi, Minseok Han, William L. Lowe, Jr.,, Alisa K. Manning, Hak Chul Jang, Kyong Soo Park, Soo Heon Kwak
Journal: Diabetes Care
Diabetes Care 2024;47(9):1622–1629
https://doi.org/10.2337/dc24-0022
Published: 28 June 2024
View articletitled, Genome-Wide Polygenic Risk Score Predicts Incident Type 2 Diabetes in Women With History of Gestational Diabetes
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Journal Articles

Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk

Free
Deirdre K. Tobias, Alisa K. Manning, Jennifer Wessel, Sridharan Raghavan, Kenneth E. Westerman, Alexander G. Bick, Daniel Dicorpo, Eric A. Whitsel, Jason Collins, Adolfo Correa, L. Adrienne Cupples, Josée Dupuis, Mark O. Goodarzi, Xiuqing Guo, Barbara Howard, Leslie A. Lange, Simin Liu, Laura M. Raffield, Alex P. Reiner, Stephen S. Rich, Kent D. Taylor, Lesley Tinker, James G. Wilson, Peitao Wu, April P. Carson, Ramachandran S. Vasan, Myriam Fornage, Bruce M. Psaty, Charles Kooperberg, Jerome I. Rotter, James Meigs, JoAnn E. Manson, TOPMed Diabetes Working Group and National Heart, Lung, and Blood Institute TOPMed Consortium
Journal: Diabetes Care
Diabetes Care 2023;46(11):1978–1985
https://doi.org/10.2337/dc23-0805
Published: 27 September 2023
View articletitled, Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk
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Journal Articles

Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity

Free
Sara J. Cromer, Chirag M. Lakhani, Josep M. Mercader, Timothy D. Majarian, Philip Schroeder, Joanne B. Cole, Jose C. Florez, Chirag J. Patel, Alisa K. Manning, Sherri-Ann M. Burnett-Bowie, Jordi Merino, Miriam S. Udler
Journal: Diabetes Care
Diabetes Care 2023;46(5):944–952
https://doi.org/10.2337/dc22-1954
Published: 14 February 2023
View articletitled, Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity
Open the PDF for Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity in another window
Journal Articles

Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms

Free
Aaron J. Deutsch, Lauren Stalbow, Timothy D. Majarian, Josep M. Mercader, Alisa K. Manning, Jose C. Florez, Ruth J.F. Loos, Miriam S. Udler
Journal: Diabetes Care
Diabetes Care 2023;46(4):794–800
https://doi.org/10.2337/dc22-1833
Published: 06 February 2023
View articletitled, Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms
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Journal Articles

Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts

Free
Daniel DiCorpo, Jessica LeClair, Joanne B. Cole, Chloé Sarnowski, Fariba Ahmadizar, Lawrence F. Bielak, Anneke Blokstra, Erwin P. Bottinger, Layal Chaker, Yii-Der I. Chen, Ye Chen, Paul S. de Vries, Tariq Faquih, Mohsen Ghanbari, Valborg Gudmundsdottir, Xiuqing Guo, Natalie R. Hasbani, Dorina Ibi, M. Arfan Ikram, Maryam Kavousi, Hampton L. Leonard, Aaron Leong, Josep M. Mercader, Alanna C. Morrison, Girish N. Nadkarni, Mike A. Nalls, Raymond Noordam, Michael Preuss, Jennifer A. Smith, Stella Trompet, Petra Vissink, Jie Yao, Wei Zhao, Eric Boerwinkle, Mark O. Goodarzi, Vilmundur Gudnason, J. Wouter Jukema, Sharon L.R. Kardia, Ruth J.F. Loos, Ching-Ti Liu, Alisa K. Manning, Dennis Mook-Kanamori, James S. Pankow, H. Susan J. Picavet, Naveed Sattar, Eleanor M. Simonsick, W.M. Monique Verschuren, Ko Willems van Dijk, Jose C. Florez, Jerome I. Rotter, James B. Meigs, Josée Dupuis, Miriam S. Udler
Journal: Diabetes Care
Diabetes Care 2022;45(3):674–683
https://doi.org/10.2337/dc21-1395
Published: 27 January 2022
View articletitled, Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
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Journal Articles

TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

Free
Shylaja Srinivasan, Varinderpal Kaur, Bindu Chamarthi, Katherine R. Littleton, Ling Chen, Alisa K. Manning, Jordi Merino, Melissa K. Thomas, Margo Hudson, Allison Goldfine, Jose C. Florez
Journal: Diabetes Care
Diabetes Care 2018;41(3):554–561
https://doi.org/10.2337/dc17-1386
Published: 11 January 2018
View articletitled, TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)
Open the PDF for TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH) in another window
Includes: Supplementary data
Journal Articles

Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms

Open Access
Jose M. de Miguel-Yanes, MD, MBA, Peter Shrader, MS, Michael J. Pencina, PHD, Caroline S. Fox, MD, MPH, Alisa K. Manning, MA, Richard W. Grant, MD, MPH, Josèe Dupuis, PHD, Jose C. Florez, MD, PHD, Ralph B. D'Agostino, Sr, PHD, L. Adrienne Cupples, PHD, James B. Meigs, MD, MPH, the MAGIC Investigators, the DIAGRAM+ Investigators
Journal: Diabetes Care
Diabetes Care 2011;34(1):121–125
https://doi.org/10.2337/dc10-1265
Published: 10 October 2010
View articletitled, Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms
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Includes: Supplementary data