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MODY Calculator and Clinical Features Routinely Used to Distinguish MODY From Type 2 Diabetes in Adults Perform Poorly for Youth Clinically Diagnosed With Type 2 Diabetes

Raymond J. Kreienkamp, Beverley M. Shields, Toni I. Pollin, Amy S. Shah, Angela D. Liese, Anna Bellatorre, Catherine Pihoker, Mustafa Tosur, Jose C. Florez, Shylaja Srinivasan, Andrew T. Hattersley, Miriam S. Udler, Maria J. Redondo

Diabetes Care 2025;48(1):e3–e5

https://doi.org/10.2337/dc24-1565

Published: 18 November 2024

View articletitled, MODY Calculator and Clinical Features Routinely Used to Distinguish MODY From Type 2 Diabetes in Adults Perform Poorly for Youth Clinically Diagnosed With Type 2 Diabetes

Journal Articles

Comment on Garvey et al. Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial. Diabetes Care 2024;47:562–570

Pedro Cardoso, Katie G. Young, Andrew T. Hattersley, Beverley M. Shields, Angus G. Jones, John M. Dennis

Diabetes Care 2024;47(9):e70–e71

https://doi.org/10.2337/dc24-0885

Published: 27 August 2024

View articletitled, Comment on Garvey et al. Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial. Diabetes Care 2024;47:562–570

Journal Articles

Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study

Angus G. Jones, Beverley M. Shields, Richard A. Oram, Dana M. Dabelea, William A. Hagopian, Seth A. Sharp, Eva Lustigova, Amy S. Shah, Julieanne Knupp, Amy K. Mottl, Ralph B. D’Agostino, Jr., Adrienne Williams, Santica M. Marcovina, Catherine Pihoker, Jasmin Divers, Maria J. Redondo

Diabetes Care 2024;47(12):2110–2119

https://doi.org/10.2337/dc23-1815

Published: 22 January 2024

View articletitled, Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study

Journal Articles

Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes

Nicholas J. Thomas, Anita V. Hill, Colin M. Dayan, Richard A. Oram, Timothy J. McDonald, Beverley M. Shields, Angus G. Jones, StartRight Study Group, Godwin Simon, Dr, Angelo Ramos, Andrea Norris, Dr, Kai Tan, Dr, Parth Narendran, Dr, Shenaz Ramtoola, Dr, Amar Ali, Dr, Moulinath Banerjee, Dr, Augustin Brooks, Dr, Ali Chakera, Dr, Andrew Johnson, Dr, Danijela Tatovic, Dr, Chitrabhanu Ballav, Dr, Colin Dayan, Prof, Sunil Nair, Dr, Francis Game, Prof, Susan Beames, Gerry Rayman, Prof, Marie Snell, Susie Butler, Sarah Beck, Janet Beecham, John Wilding, Prof, Sam Rice, Dr, Mimi Chen, Dr, Athinyaa Thiraviaraj, Dr, Siva Sivappriyan, Dr, Basil Issa, Dr, Asif Humayun, Dr, Rebecca Hinch, Leena Krishnan, Dr, Khin Swe Myint, Dr, Charles Fox, Dr, Jennifer Prouten, Dr, Mike Sampson, Prof, Peter Mansell, Dr, Carolyn Chee, Dr, Katherine Owen, Dr, Ioannis Dimitropoulis, Dr, Michael Cummings, Prof, Foteini Kavourra, Dr, Adrian Heald, Dr, Simon Heller, Prof, Sarbpreet Sihota, Dr, Vakkat Muraleedharan, Dr, Tara Watson, Dr, Hermione Price, Dr, Roger Whittaker, Sarah Orme, Ben Field, Dr, Stephen Bain, Prof, Beas Battacharya, Dr, Lesley Haxton, Suzannah Pegler, Catherine Thompson, Rob Andrew, Prof, Jamie Smith, Dr, Duncan Browne, Dr, Steve Creely, Dr, Rahul Yadav, Dr, Rakhi Kakad, Dr, Ken Laji, Dr, Mohit Kumar, Dr, Alirezi Mohammadi, Dr, James Young, Dr, Seshadri Pramodh, Dr, Vijay Jayagopal, Dr, Angus Jones, Dr, Anita Hill, Robert Bolt, Suzanne Hammersley, Migaila Aldred, Anna Steele, Peter Tippett

Diabetes Care 2023;46(6):1156–1163

https://doi.org/10.2337/dc22-2159

Published: 21 February 2023

View articletitled, Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes

Journal Articles

Routine Islet Autoantibody Testing in Clinically Diagnosed Adult-Onset Type 1 Diabetes Can Help Identify Misclassification and the Possibility of Successful Insulin Cessation

Russell J. Eason, Nicholas J. Thomas, Anita V. Hill, Bridget A. Knight, Alice Carr, Andrew T. Hattersley, Timothy J. McDonald, Beverley M. Shields, Angus G. Jones, for the StartRight Study Group, Godwin Simon, Angelo Ramos, Andrea Norris, Kai Tan, Parth Narendran, Shenaz Ramtoola, Amar Ali, Moulinath Banerjee, Augustin Brooks, Ali Chakera, Andrew Johnson, Danijela Tatovic, Chitrabhanu Ballav, Colin Dayan, Sunil Nair, Frances Game, Angus Jones, Susan Beames, Gerry Rayman, Marie Snell, Susie Butler, Sarah Beck, Janet Beecham, John Wilding, Sam Rice, Mimi Chen, Athinyaa Thiraviaraj, Siva Sivappriyan, Basil Issa, Asif Humayun, Rebecca Hinch, Leena Krishnan, Khin Swe Myint, Charles Fox, Jennifer Prouten, Mike Sampson, Peter Mansell, Carolyn Chee, Katharine Owen, Ioannis Dimitropoulis, Michael Cummings, Foteini Kavourra, Adrian Heald, Simon Heller, Sarbpreet Sihota, Vakkat Muraleedharan, Tara Watson, Hermione Price, Roger Whittaker, Sarah Orme, Ben Field, Stephen Bain, Beas Battacharya, Lesley Haxton, Suzannah Pegler, Catherine Thompson, Rob Andrew, Jamie Smith, Duncan Browne, Steve Creely, Rahul Yadav, Rakhi Kakad, Ken Laji, Mohit Kumar, Alirezi Mohammadi, James Young, Seshadri Pramodh, Vijay Jayagopal

Diabetes Care 2022;45(12):2844–2851

https://doi.org/10.2337/dc22-0623

Published: 07 October 2022

View articletitled, Routine Islet Autoantibody Testing in Clinically Diagnosed Adult-Onset Type 1 Diabetes Can Help Identify Misclassification and the Possibility of Successful Insulin Cessation

Journal Articles

Improvements in Awareness and Testing Have Led to a Threefold Increase Over 10 Years in the Identification of Monogenic Diabetes in the U.K.

Lewis Pang, Kevin C. Colclough, Maggie H. Shepherd, Joanne McLean, Ewan R. Pearson, Sian Ellard, Andrew T. Hattersley, Beverley M. Shields

Diabetes Care 2022;45(3):642–649

https://doi.org/10.2337/dc21-2056

Published: 21 January 2022

View articletitled, Improvements in Awareness and Testing Have Led to a Threefold Increase Over 10 Years in the Identification of Monogenic Diabetes in the U.K.

Journal Articles

Latent Autoimmune Diabetes of Adults (LADA) Is Likely to Represent a Mixed Population of Autoimmune (Type 1) and Nonautoimmune (Type 2) Diabetes

Angus G. Jones, Timothy J. McDonald, Beverley M. Shields, William Hagopian, Andrew T. Hattersley

Diabetes Care 2021;44(6):1243–1251

https://doi.org/10.2337/dc20-2834

Published: 18 June 2021

View articletitled, Latent Autoimmune Diabetes of Adults (LADA) Is Likely to Represent a Mixed Population of Autoimmune (Type 1) and Nonautoimmune (Type 2) Diabetes

Journal Articles

Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes

Kashyap A. Patel, Michael N. Weedon, Beverley M. Shields, Ewan R. Pearson, Andrew T. Hattersley, Timothy J. McDonald

Diabetes Care 2019;42(2):e16–e17

https://doi.org/10.2337/dc18-0373

Published: 08 November 2018

View articletitled, Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes

Journal Articles

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody–Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Anita L. Grubb, Timothy J. McDonald, Femke Rutters, Louise A. Donnelly, Andrew T. Hattersley, Richard A. Oram, Colin N.A. Palmer, Amber A. van der Heijden, Fiona Carr, Petra J.M. Elders, Mike N. Weedon, Roderick C. Slieker, Leen M. ’t Hart, Ewan R. Pearson, Beverley M. Shields, Angus G. Jones

Diabetes Care 2019;42(2):208–214

https://doi.org/10.2337/dc18-0431

Published: 23 October 2018

View articletitled, A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody–Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Includes: Supplementary data

Journal Articles

Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data

Diabetes Care 2018;41(9):1844–1853

https://doi.org/10.2337/dc18-0344

Published: 02 August 2018

View articletitled, Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data

Includes: Supplementary data

Journal Articles

C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase

Beverley M. Shields, Timothy J. McDonald, Richard Oram, Anita Hill, Michelle Hudson, Pia Leete, Ewan R. Pearson, Sarah J. Richardson, Noel G. Morgan, Andrew T. Hattersley, The TIGI Consortium, Bart O. Roep, Tim I. Tree, Suzy Hammersley, Robert Bolt, Anita V. Hill

Diabetes Care 2018;41(7):1486–1492

https://doi.org/10.2337/dc18-0465

Published: 07 June 2018

View articletitled, C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase

Includes: Supplementary data

Journal Articles

Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy

John M. Dennis, Beverley M. Shields, Anita V. Hill, Bridget A. Knight, Timothy J. McDonald, Lauren R. Rodgers, Michael N. Weedon, William E. Henley, Naveed Sattar, Rury R. Holman, Ewan R. Pearson, Andrew T. Hattersley, Angus G. Jones

Diabetes Care 2018;41(4):705–712

https://doi.org/10.2337/dc17-1827

Published: 31 January 2018

View articletitled, Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy

Includes: Supplementary data

Journal Articles

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Beverley M. Shields, Maggie Shepherd, Michelle Hudson, Timothy J. McDonald, Kevin Colclough, Jaime Peters, Bridget Knight, Chris Hyde, Sian Ellard, Ewan R. Pearson, Andrew T. Hattersley

Diabetes Care 2017;40(8):1017–1025

https://doi.org/10.2337/dc17-0224

Published: 11 July 2017

View articletitled, Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Includes: Supplementary data

Journal Articles

Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes

Angus G. Jones, Timothy J. McDonald, Beverley M. Shields, Anita V. Hill, Christopher J. Hyde, Bridget A. Knight, Andrew T. Hattersley

Diabetes Care 2016;39(2):250–257

https://doi.org/10.2337/dc15-0258

Published: 04 August 2015

View articletitled, Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes

Includes: Supplementary data

Journal Articles

Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors

Richard A. Oram, Timothy J. McDonald, Beverley M. Shields, Michelle M. Hudson, Maggie H. Shepherd, Suzanne Hammersley, Ewan R. Pearson, Andrew T. Hattersley, on behalf of the UNITED Team

Diabetes Care 2015;38(2):323–328

https://doi.org/10.2337/dc14-0871

Published: 17 December 2014

View articletitled, Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors

Includes: Supplementary data

Journal Articles

Effect of the Holiday Season in Patients With Diabetes: Glycemia and Lipids Increase Postholiday, but the Effect Is Small and Transient

Angus G. Jones, Timothy J. McDonald, Andrew T. Hattersley, Beverley M. Shields

Diabetes Care 2014;37(5):e98–e99

https://doi.org/10.2337/dc13-2353

Published: 10 April 2014

View articletitled, Effect of the Holiday Season in Patients With Diabetes: Glycemia and Lipids Increase Postholiday, but the Effect Is Small and Transient

Journal Articles

Response to Comment on: Besser et al. Lessons From the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195–201

Beverley M. Shields, PHD, William Henley, PHD, Rachel E.J. Besser, PHD, Andrew T. Hattersley, DM, Johnny Ludvigsson, PHD

Diabetes Care 2013;36(12):e222

https://doi.org/10.2337/dc13-0609

Published: 13 November 2013

View articletitled, Response to Comment on: Besser et al. Lessons From the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195–201

Includes: Supplementary data

Journal Articles

Lessons From the Mixed-Meal Tolerance Test: Use of 90-minute and fasting C-peptide in pediatric diabetes

Rachel E.J. Besser, PHD, Beverley M. Shields, PHD, Rosaura Casas, PHD, Andrew T. Hattersley, DM, Johnny Ludvigsson, MD

Diabetes Care 2013;36(2):195–201

https://doi.org/10.2337/dc12-0836

Published: 17 January 2013

View articletitled, Lessons From the Mixed-Meal Tolerance Test: Use of 90-minute and fasting C-peptide in pediatric diabetes

Includes: Supplementary data

Journal Articles

High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

Tim J. McDonald, MSC, Beverley M. Shields, PHD, Jane Lawry, BSC, Katharine R. Owen, MD, Anna L. Gloyn, DPHIL, Sian Ellard, PHD, Andrew T. Hattersley, DM

Diabetes Care 2011;34(8):1860–1862

https://doi.org/10.2337/dc11-0323

Published: 16 July 2011

View articletitled, High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

Includes: Supplementary data

Journal Articles

Urine C-Peptide Creatinine Ratio Is a Noninvasive Alternative to the Mixed-Meal Tolerance Test in Children and Adults With Type 1 Diabetes

Rachel E.J. Besser, MBBS, Johnny Ludvigsson, PHD, Angus G. Jones, MBBS, Timothy J. McDonald, MSC, Beverley M. Shields, PHD, Bridget A. Knight, PHD, Andrew T. Hattersley, DM

Diabetes Care 2011;34(3):607–609

https://doi.org/10.2337/dc10-2114

Published: 17 February 2011

View articletitled, Urine C-Peptide Creatinine Ratio Is a Noninvasive Alternative to the Mixed-Meal Tolerance Test in Children and Adults With Type 1 Diabetes

Includes: Supplementary data

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MODY Calculator and Clinical Features Routinely Used to Distinguish MODY From Type 2 Diabetes in Adults Perform Poorly for Youth Clinically Diagnosed With Type 2 Diabetes

Comment on Garvey et al. Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial. Diabetes Care 2024;47:562–570

Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study

Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes

Routine Islet Autoantibody Testing in Clinically Diagnosed Adult-Onset Type 1 Diabetes Can Help Identify Misclassification and the Possibility of Successful Insulin Cessation

Improvements in Awareness and Testing Have Led to a Threefold Increase Over 10 Years in the Identification of Monogenic Diabetes in the U.K.

Latent Autoimmune Diabetes of Adults (LADA) Is Likely to Represent a Mixed Population of Autoimmune (Type 1) and Nonautoimmune (Type 2) Diabetes

Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody–Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data

C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase

Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes

Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors

Effect of the Holiday Season in Patients With Diabetes: Glycemia and Lipids Increase Postholiday, but the Effect Is Small and Transient

Response to Comment on: Besser et al. Lessons From the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195–201

Lessons From the Mixed-Meal Tolerance Test: Use of 90-minute and fasting C-peptide in pediatric diabetes

High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

Urine C-Peptide Creatinine Ratio Is a Noninvasive Alternative to the Mixed-Meal Tolerance Test in Children and Adults With Type 1 Diabetes

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