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Darren K. McGuire
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Journal Articles

Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity

Matthew M.Y. Lee, Nazim Ghouri, Anoop Misra, Yu Mi Kang, Martin K. Rutter, Hertzel C. Gerstein, Darren K. McGuire, Naveed Sattar
Journal: Diabetes Care
Diabetes Care 2025;48(3):489–493
https://doi.org/10.2337/dc24-1533
Published: 20 February 2025
View article titled, Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity
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Journal Articles

Is This the Real Life? Real-World Evidence of Empagliflozin in Health Care Resource Utilization and Cost

Josephine Harrington, Yu Mi Kang, Darren K. McGuire
Journal: Diabetes Care
Diabetes Care 2024;47(11):1897–1899
https://doi.org/10.2337/dci24-0061
Published: 21 October 2024
View article titled, Is This the Real Life? Real-World Evidence of Empagliflozin in Health Care Resource Utilization and Cost
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Journal Articles

Cardiovascular and Kidney Risks in Individuals With Type 2 Diabetes: Contemporary Understanding With Greater Emphasis on Excess Adiposity

Naveed Sattar, Calum Presslie, Martin K. Rutter, Darren K. McGuire
Journal: Diabetes Care
Diabetes Care 2024;47(4):531–543
https://doi.org/10.2337/dci23-0041
Published: 27 February 2024
View article titled, Cardiovascular and Kidney Risks in Individuals With Type 2 Diabetes: Contemporary Understanding With Greater Emphasis on Excess Adiposity
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Journal Articles

Risk Factors for and Risk of Peripheral Artery Disease in Swedish Individuals With Type 2 Diabetes: A Nationwide Register-Based Study

Tarik Avdic, Hanne K. Carlsen, Rikard Isaksson, Soffia Gudbjörnsdottir, Zacharias Mandalenakis, Stefan Franzén, Naveed Sattar, Joshua A. Beckman, Darren K. McGuire, Björn Eliasson
Journal: Diabetes Care
Diabetes Care 2024;47(1):109–116
https://doi.org/10.2337/dc23-1198
Published: 02 November 2023
View article titled, Risk Factors for and Risk of Peripheral Artery Disease in Swedish Individuals With Type 2 Diabetes: A Nationwide Register-Based Study
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Journal Articles

Efficacy and Safety of Dapagliflozin by Baseline Insulin Regimen and Dose: Post Hoc Analyses From DECLARE-TIMI 58

Rena Pollack, Itamar Raz, Stephen D. Wiviott, Erica L. Goodrich, Sabina A. Murphy, Ilan Yanuv, Aliza Rozenberg, Ofri Mosenzon, Anna Maria Langkilde, Ingrid A.M. Gause-Nilsson, Deepak L. Bhatt, Lawrence A. Leiter, Darren K. McGuire, John P.H. Wilding, Marc S. Sabatine, Avivit Cahn
Journal: Diabetes Care
Diabetes Care 2023;46(1):156–164
https://doi.org/10.2337/dc22-1318
Published: 18 November 2022
View article titled, Efficacy and Safety of Dapagliflozin by Baseline Insulin Regimen and Dose: Post Hoc Analyses From DECLARE-TIMI 58
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Journal Articles

Dapagliflozin and Prevention of Kidney Disease Among Patients With Type 2 Diabetes: Post Hoc Analyses From the DECLARE-TIMI 58 Trial

Ofri Mosenzon, Itamar Raz, Stephen D. Wiviott, Meir Schechter, Erica L. Goodrich, Ilan Yanuv, Aliza Rozenberg, Sabina A. Murphy, Thomas A. Zelniker, Anna Maria Langkilde, Ingrid A.M. Gause-Nilsson, Martin Fredriksson, Peter A. Johansson, John P.H. Wilding, Darren K. McGuire, Deepak L. Bhatt, Lawrence A. Leiter, Avivit Cahn, Jamie P. Dwyer, Hiddo J.L. Heerspink, Marc S. Sabatine
Journal: Diabetes Care
Diabetes Care 2022;45(10):2350–2359
https://doi.org/10.2337/dc22-0382
Published: 23 August 2022
View article titled, Dapagliflozin and Prevention of Kidney Disease Among Patients With Type 2 Diabetes: Post Hoc Analyses From the DECLARE-TIMI 58 Trial
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Journal Articles

Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes

Evangelos K. Oikonomou, Marc A. Suchard, Darren K. McGuire, Rohan Khera
Journal: Diabetes Care
Diabetes Care 2022;45(4):965–974
https://doi.org/10.2337/dc21-1765
Published: 04 February 2022
View article titled, Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes
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Journal Articles

Effect of Dapagliflozin on Hematocrit in Patients With Type 2 Diabetes at High Cardiovascular Risk: Observations From DECLARE-TIMI 58

Ahmed A. Kolkailah, Stephen D. Wiviott, Itamar Raz, Sabina A. Murphy, Ofri Mosenzon, Deepak L. Bhatt, Lawrence A. Leiter, John P.H. Wilding, Ingrid Gause-Nilsson, Marc S. Sabatine, Darren K. McGuire
Journal: Diabetes Care
Diabetes Care 2022;45(2):e27–e29
https://doi.org/10.2337/dc21-1668
Published: 17 January 2022
View article titled, Effect of Dapagliflozin on Hematocrit in Patients With Type 2 Diabetes at High Cardiovascular Risk: Observations From DECLARE-TIMI 58
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Journal Articles

Association of Baseline HbA1c With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58

Avivit Cahn, Stephen D. Wiviott, Ofri Mosenzon, Erica L. Goodrich, Sabina A. Murphy, Ilan Yanuv, Aliza Rozenberg, Deepak L. Bhatt, Lawrence A. Leiter, Darren K. McGuire, John P.H. Wilding, Ingrid A.M. Gause-Nilsson, Anna Maria Langkilde, Marc S. Sabatine, Itamar Raz
Journal: Diabetes Care
Diabetes Care 2022;45(4):938–946
https://doi.org/10.2337/dc21-1744
Published: 11 January 2022
View article titled, Association of Baseline HbA<sub>1c</sub> With Cardiovascular and Renal Outcomes: Analyses From DECLARE-TIMI 58
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Journal Articles

Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine

Abhinav Sharma, Yinggan Zheng, Justin A. Ezekowitz, Cynthia M. Westerhout, Jacob A. Udell, Shaun G. Goodman, Paul W. Armstrong, John B. Buse, Jennifer B. Green, Robert G. Josse, Keith D. Kaufman, Darren K. McGuire, Giuseppe Ambrosio, Lee-Ming Chuang, Renato D. Lopes, Eric D. Peterson, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2022;45(1):204–212
https://doi.org/10.2337/dc20-2806
Published: 29 October 2021
View article titled, Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine
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Journal Articles

A Biomarker-Based Score for Risk of Hospitalization for Heart Failure in Patients With Diabetes

David D. Berg, Stephen D. Wiviott, Benjamin M. Scirica, Thomas A. Zelniker, Erica L. Goodrich, Petr Jarolim, Ofri Mosenzon, Avivit Cahn, Deepak L. Bhatt, Lawrence A. Leiter, Darren K. McGuire, John P.H. Wilding, Per Johanson, Anna Maria Langkilde, Itamar Raz, Eugene Braunwald, Marc S. Sabatine, David A. Morrow
Journal: Diabetes Care
Diabetes Care 2021;44(11):2573–2581
https://doi.org/10.2337/dc21-1170
Published: 17 September 2021
View article titled, A Biomarker-Based Score for Risk of Hospitalization for Heart Failure in Patients With Diabetes
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Journal Articles

The Effect of Dapagliflozin on Albuminuria in DECLARE-TIMI 58

Ofri Mosenzon, Stephen D. Wiviott, Hiddo J.L. Heerspink, Jamie P. Dwyer, Avivit Cahn, Erica L. Goodrich, Aliza Rozenberg, Meir Schechter, Ilan Yanuv, Sabina A. Murphy, Thomas A. Zelniker, Ingrid A.M. Gause-Nilsson, Anna Maria Langkilde, Martin Fredriksson, Peter A. Johansson, Deepak L. Bhatt, Lawrence A. Leiter, Darren K. McGuire, John P.H. Wilding, Marc S. Sabatine, Itamar Raz
Journal: Diabetes Care
Diabetes Care 2021;44(8):1805–1815
https://doi.org/10.2337/dc21-0076
Published: 11 August 2021
View article titled, The Effect of Dapagliflozin on Albuminuria in DECLARE-TIMI 58
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Journal Articles

Meta-analyses of Results From Randomized Outcome Trials Comparing Cardiovascular Effects of SGLT2is and GLP-1RAs in Asian Versus White Patients With and Without Type 2 Diabetes

Matthew M.Y. Lee, Nazim Ghouri, Darren K. McGuire, Martin K. Rutter, Naveed Sattar
Journal: Diabetes Care
Diabetes Care 2021;44(5):1236–1241
https://doi.org/10.2337/dc20-3007
Published: 11 March 2021
View article titled, Meta-analyses of Results From Randomized Outcome Trials Comparing Cardiovascular Effects of SGLT2is and GLP-1RAs in Asian Versus White Patients With and Without Type 2 Diabetes
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Journal Articles

Cardiovascular, Renal, and Metabolic Outcomes of Dapagliflozin Versus Placebo in a Primary Cardiovascular Prevention Cohort: Analyses From DECLARE-TIMI 58

Avivit Cahn, Itamar Raz, Lawrence A. Leiter, Ofri Mosenzon, Sabina A. Murphy, Erica L. Goodrich, Ilan Yanuv, Aliza Rozenberg, Deepak L. Bhatt, Darren K. McGuire, John P.H. Wilding, Ingrid A.M. Gause-Nilsson, Anna Maria Langkilde, Marc S. Sabatine, Stephen D. Wiviott
Journal: Diabetes Care
Diabetes Care 2021;44(5):1159–1167
https://doi.org/10.2337/dc20-2492
Published: 02 March 2021
View article titled, Cardiovascular, Renal, and Metabolic Outcomes of Dapagliflozin Versus Placebo in a Primary Cardiovascular Prevention Cohort: Analyses From DECLARE-TIMI 58
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Journal Articles

Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies

Anne L. Peters, Darren K. McGuire, Thomas Danne, Jake A. Kushner, Helena W. Rodbard, Ketan Dhatariya, Sangeeta Sawhney, Phillip Banks, Wenjun Jiang, Michael J. Davies, Pablo Lapuerta
Journal: Diabetes Care
Diabetes Care 2020;43(11):2713–2720
https://doi.org/10.2337/dc20-0924
Published: 14 September 2020
View article titled, Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies
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Journal Articles

Medicaid Expansion and Utilization of Antihyperglycemic Therapies

Andrew Sumarsono, Leo F. Buckley, Sara R. Machado, Rishi K. Wadhera, Haider J. Warraich, Rishi J. Desai, Brendan M. Everett, Darren K. McGuire, Gregg C. Fonarow, Javed Butler, Ambarish Pandey, Muthiah Vaduganathan
Journal: Diabetes Care
Diabetes Care 2020;43(11):2684–2690
https://doi.org/10.2337/dc20-0735
Published: 04 September 2020
View article titled, Medicaid Expansion and Utilization of Antihyperglycemic Therapies
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Journal Articles

Effects of Liraglutide on Cardiovascular Outcomes in Type 2 Diabetes Patients With and Without Baseline Metformin Use: Post Hoc Analyses of the LEADER Trial

Matthew J. Crowley, Darren K. McGuire, Anastasia-Stefania Alexopoulos, Thomas Jon Jensen, Søren Rasmussen, Hans A. Saevereid, Subodh Verma, John B. Buse
Journal: Diabetes Care
Diabetes Care 2020;43(9):e108–e110
https://doi.org/10.2337/dc20-0437
Published: 09 July 2020
View article titled, Effects of Liraglutide on Cardiovascular Outcomes in Type 2 Diabetes Patients With and Without Baseline Metformin Use: Post Hoc Analyses of the LEADER Trial
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Journal Articles

Association of Long-term Change and Variability in Glycemia With Risk of Incident Heart Failure Among Patients With Type 2 Diabetes: A Secondary Analysis of the ACCORD Trial

Matthew W. Segar, Kershaw V. Patel, Muthiah Vaduganathan, Melissa C. Caughey, Javed Butler, Gregg C. Fonarow, Justin L. Grodin, Darren K. McGuire, Ambarish Pandey
Journal: Diabetes Care
Diabetes Care 2020;43(8):1920–1928
https://doi.org/10.2337/dc19-2541
Published: 15 June 2020
View article titled, Association of Long-term Change and Variability in Glycemia With Risk of Incident Heart Failure Among Patients With Type 2 Diabetes: A Secondary Analysis of the ACCORD Trial
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Journal Articles

Effects of Linagliptin on Cardiovascular and Kidney Outcomes in People With Normal and Reduced Kidney Function: Secondary Analysis of the CARMELINA Randomized Trial

Vlado Perkovic, Robert Toto, Mark E. Cooper, Johannes F.E. Mann, Julio Rosenstock, Darren K. McGuire, Steven E. Kahn, Nikolaus Marx, John H. Alexander, Bernard Zinman, Egon Pfarr, Sven Schnaidt, Thomas Meinicke, Maximillian von Eynatten, Jyothis T. George, Odd Erik Johansen, Christoph Wanner
Journal: Diabetes Care
Diabetes Care 2020;43(8):1803–1812
https://doi.org/10.2337/dc20-0279
Published: 22 May 2020
View article titled, Effects of Linagliptin on Cardiovascular and Kidney Outcomes in People With Normal and Reduced Kidney Function: Secondary Analysis of the CARMELINA Randomized Trial
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Journal Articles

Response to Comment on Segar et al. Machine Learning to Predict the Risk of Incident Heart Failure Hospitalization Among Patients With Diabetes: The WATCH-DM Risk Score. Diabetes Care 2019;42:2298–2306

Matthew W. Segar, Muthiah Vaduganathan, Darren K. McGuire, Mujeeb Basit, Ambarish Pandey
Journal: Diabetes Care
Diabetes Care 2020;43(2):e26–e27
https://doi.org/10.2337/dci19-0059
Published: 13 January 2020
View article titled, Response to Comment on Segar et al. Machine Learning to Predict the Risk of Incident Heart Failure Hospitalization Among Patients With Diabetes: The WATCH-DM Risk Score. Diabetes Care 2019;42:2298–2306
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