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Filip K. Knop
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Journal Articles

Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial

Casper K. Nielsen, Caroline C. Øhrstrøm, Inas J.K. Houji, Mads M. Helsted, Liva S.L. Krogh, Nicklas J. Johansen, Bolette Hartmann, Jens J. Holst, Tina Vilsbøll, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2023;46(12):2208–2217
https://doi.org/10.2337/dc23-1193
Published: 11 October 2023
View article titled, Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial
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Journal Articles

Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Mille Baekdal, Sophie W. Nielsen, Carsten P. Hansen, Jan H. Storkholm, Gerrit van Hall, Bolette Hartmann, Jens J. Holst, Tina Vilsbøll, Asger Lund, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2024;47(1):71–80
https://doi.org/10.2337/dc23-0645
Published: 13 September 2023
View article titled, Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study
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Journal Articles

Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes

Coco M. Fuhri Snethlage, Timothy J. McDonald, Richard D. Oram, Pleun de Groen, Elena Rampanelli, Alinda W.M. Schimmel, Frits Holleman, Sarah Siegelaar, Joost Hoekstra, Catherine B. Brouwer, Filip K. Knop, C. Bruce Verchere, Daniël H. van Raalte, Bart O. Roep, Max Nieuwdorp, Nordin M.J. Hanssen
Journal: Diabetes Care
Diabetes Care 2024;47(7):1114–1121
https://doi.org/10.2337/dc23-0776
Published: 03 August 2023
View article titled, Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes
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Journal Articles

Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

Casper K. Nielsen, Caroline C. Øhrstrøm, Urd L. Kielgast, Dorte L. Hansen, Bolette Hartmann, Jens J. Holst, Asger Lund, Tina Vilsbøll, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2022;45(6):1476–1481
https://doi.org/10.2337/dc21-2252
Published: 23 March 2022
View article titled, Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
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Journal Articles

Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)

Alexander S. Christensen, Sofie Hædersdal, Julie Støy, Heidi Storgaard, Ulla Kampmann, Julie L. Forman, Marta Seghieri, Jens J. Holst, Torben Hansen, Filip K. Knop, Tina Vilsbøll
Journal: Diabetes Care
Diabetes Care 2020;43(9):2025–2033
https://doi.org/10.2337/dc20-0408
Published: 13 July 2020
View article titled, Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)
Open the PDF for Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA) in another window
Journal Articles

No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

Natasha C. Bergmann, Lærke S. Gasbjerg, Sebastian M. Heimbürger, Liva S.L. Krogh, Flemming Dela, Bolette Hartmann, Jens J. Holst, Lene Jessen, Mikkel B. Christensen, Tina Vilsbøll, Asger Lund, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2020;43(3):588–596
https://doi.org/10.2337/dc19-0578
Published: 16 January 2020
View article titled, No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes
Open the PDF for No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes in another window
Includes: Supplementary data
Journal Articles

Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts

Yuki M.F. Andersen, Alexander Egeberg, Lu Ban, Sonia Gran, Hywel C. Williams, Nick A. Francis, Filip K. Knop, Gunnar H. Gislason, Lone Skov, Jacob P. Thyssen
Journal: Diabetes Care
Diabetes Care 2019;42(6):1095–1103
https://doi.org/10.2337/dc18-2158
Published: 01 April 2019
View article titled, Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts
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Includes: Supplementary data
Journal Articles

Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers

Magnus F. Grøndahl, Jonatan I. Bagger, Asger Lund, Annesofie Faurschou, Jens F. Rehfeld, Jens J. Holst, Tina Vilsbøll, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2018;41(6):1260–1267
https://doi.org/10.2337/dc17-1818
Published: 30 March 2018
View article titled, Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers
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Includes: Supplementary data
Journal Articles

Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference

Signe Foghsgaard, Camilla Andreasen, Louise Vedtofte, Emilie S. Andersen, Emilie Bahne, Charlotte Strandberg, Thora Buhl, Jens J. Holst, Jens A. Svare, Tine D. Clausen, Elisabeth R. Mathiesen, Peter Damm, Lise L. Gluud, Filip K. Knop, Tina Vilsbøll
Journal: Diabetes Care
Diabetes Care 2017;40(1):109–116
https://doi.org/10.2337/dc16-1017
Published: 03 November 2016
View article titled, Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
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Journal Articles

GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes

Thea A.S. Halden, Erlend J. Egeland, Anders Åsberg, Anders Hartmann, Karsten Midtvedt, Hassan Z. Khiabani, Jens J. Holst, Filip K. Knop, Mads Hornum, Bo Feldt-Rasmussen, Trond Jenssen
Journal: Diabetes Care
Diabetes Care 2016;39(4):617–624
https://doi.org/10.2337/dc15-2383
Published: 23 February 2016
View article titled, GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
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Journal Articles

Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care 2015;38:1858–1867

David P. Sonne, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2015;38(12):e215
https://doi.org/10.2337/dc15-1794
Published: 19 November 2015
View article titled, Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care 2015;38:1858–1867
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Journal Articles

Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blind, Parallel-Group, Randomized Trial

Thomas Idorn, Filip K. Knop, Morten B. Jørgensen, Tonny Jensen, Marsela Resuli, Pernille M. Hansen, Karl B. Christensen, Jens J. Holst, Mads Hornum, Bo Feldt-Rasmussen
Journal: Diabetes Care
Diabetes Care 2016;39(2):206–213
https://doi.org/10.2337/dc15-1025
Published: 17 August 2015
View article titled, Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blind, Parallel-Group, Randomized Trial
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Includes: Supplementary data
Journal Articles

Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests

David P. Sonne, Tina Vilsbøll, Filip K. Knop
Journal: Diabetes Care
Diabetes Care 2015;38(5):e71–e72
https://doi.org/10.2337/dc14-2751
Published: 13 April 2015
View article titled, Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
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Journal Articles

Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

Signe H. Østoft, Jonatan I. Bagger, Torben Hansen, Oluf Pedersen, Jens Faber, Jens J. Holst, Filip K. Knop, Tina Vilsbøll
Journal: Diabetes Care
Diabetes Care 2014;37(7):1797–1805
https://doi.org/10.2337/dc13-3007
Published: 12 June 2014
View article titled, Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
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Includes: Supplementary data
Journal Articles

Secretion of Glucose-Dependent Insulinotropic Polypeptide in Patients With Type 2 Diabetes: Systematic review and meta-analysis of clinical studies

Salvatore Calanna, MD, Mikkel Christensen, MD, Jens J. Holst, MD, DMSC, Blandine Laferrère, MD, Lise L. Gluud, MD, DMSC, Tina Vilsbøll, MD, DMSC, Filip K. Knop, MD, PHD
Journal: Diabetes Care
Diabetes Care 2013;36(10):3346–3352
https://doi.org/10.2337/dc13-0465
Published: 14 September 2013
View article titled, Secretion of Glucose-Dependent Insulinotropic Polypeptide in Patients With Type 2 Diabetes: <subtitle>Systematic review and meta-analysis of clinical studies</subtitle>
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Includes: Supplementary data
Journal Articles

Mechanism of Metabolic Advantages After Bariatric Surgery: It’s all gastrointestinal factors versus it’s all food restriction

Filip K. Knop, MD, Roy Taylor, MD
Journal: Diabetes Care
Diabetes Care 2013;36(Supplement_2):S287–S291
https://doi.org/10.2337/dcS13-2032
Published: 17 July 2013
View article titled, Mechanism of Metabolic Advantages After Bariatric Surgery: <subtitle>It’s all gastrointestinal factors versus it’s all food restriction</subtitle>
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Journal Articles

Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes

Jens J. Holst, MD, Filip K. Knop, MD, Tina Vilsbøll, MD, Thure Krarup, MD, Sten Madsbad, MD
Journal: Diabetes Care
Diabetes Care 2011;34(Supplement_2):S251–S257
https://doi.org/10.2337/dc11-s227
Published: 22 April 2011
View article titled, Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
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Journal Articles

Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552–2554

Filip K. Knop, MD
Journal: Diabetes Care
Diabetes Care 2011;34(4):e44
https://doi.org/10.2337/dc10-2407
Published: 21 March 2011
View article titled, Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552–2554
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Journal Articles

No Hypoglycemia After Subcutaneous Administration of Glucagon-Like Peptide-1 in Lean Type 2 Diabetic Patients and in Patients With Diabetes Secondary to Chronic Pancreatitis

Filip K. Knop, MD, Tina Vilsbøll, MD, Steen Larsen, MD, DMSC, Sten Madsbad, MD, DMSC, Jens J. Holst, MD, DMSC, Thure Krarup, MD, DMSC
Journal: Diabetes Care
Diabetes Care 2003;26(9):2581–2587
https://doi.org/10.2337/diacare.26.9.2581
Published: 01 September 2003
View article titled, No Hypoglycemia After Subcutaneous Administration of Glucagon-Like Peptide-1 in Lean Type 2 Diabetic Patients and in Patients With Diabetes Secondary to Chronic Pancreatitis
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