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Journal Articles

Effect of Efpeglenatide on Heart Failure Outcomes: A Participant-Level Exploratory Analysis of the Randomized AMPLITUDE-O Trial

Free
Kelley R.H. Branch, Carolyn S.P. Lam, Shofiqul Islam, Stefano Del Prato, Renato D. Lopes, Richard Pratley, Julio Rosenstock, Naveed Sattar, Hertzel C. Gerstein
Journal: Diabetes Care
Diabetes Care dc242629
https://doi.org/10.2337/dc24-2629
Published: 09 June 2025
View article titled, Effect of Efpeglenatide on Heart Failure Outcomes: A Participant-Level Exploratory Analysis of the Randomized AMPLITUDE-O Trial
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Journal Articles

The Modern Role of Basal Insulin in Advancing Therapy in People With Type 2 Diabetes

Free
Geremia B. Bolli, Philip D. Home, Francesca Porcellati, Matthew C. Riddle, Hertzel C. Gerstein, Paola Lucidi, Carmine G. Fanelli, David R. Owens
Journal: Diabetes Care
Diabetes Care 2025;48(5):671–681
https://doi.org/10.2337/dci24-0104
Published: 21 March 2025
View article titled, The Modern Role of Basal Insulin in Advancing Therapy in People With Type 2 Diabetes
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Journal Articles

Isolated Glucosuria in Adolescence and Early-Onset Diabetes: A Nationwide Cohort Study of 1.6 Million Adolescents

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Adi Vinograd, Tsahi T. Lerman, Orit Pinhas-Hamiel, Aya Bardugo, Cole D. Bendor, Estela Derazne, Josef Coresh, Ofir Vinograd, Miri Lutski, Inbar Zucker, Michal Bromberg, Tamar Fishman, Gabriel Chodick, Hertzel C. Gerstein, Tali Cukierman-Yaffe, Asaf Vivante, Adi Leiba, Arnon Afek, Amir Tirosh, Boris Fishman, Gilad Twig
Journal: Diabetes Care
Diabetes Care 2025;48(5):763–767
https://doi.org/10.2337/dc24-2402
Published: 26 February 2025
View article titled, Isolated Glucosuria in Adolescence and Early-Onset Diabetes: A Nationwide Cohort Study of 1.6 Million Adolescents
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Journal Articles

Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity

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Matthew M.Y. Lee, Nazim Ghouri, Anoop Misra, Yu Mi Kang, Martin K. Rutter, Hertzel C. Gerstein, Darren K. McGuire, Naveed Sattar
Journal: Diabetes Care
Diabetes Care 2025;48(3):489–493
https://doi.org/10.2337/dc24-1533
Published: 20 February 2025
View article titled, Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity
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Journal Articles

A Glycemic Threshold Above Which the Improvement of β-Cell Function and Glycemia in Response to Insulin Therapy Is Amplified in Early Type 2 Diabetes: The Reversal of Glucotoxicity

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Ravi Retnakaran, Jiajie Pu, Chang Ye, Alexandra Emery, Stewart B. Harris, Sonja M. Reichert, Hertzel C. Gerstein, Natalia McInnes, Caroline K. Kramer, Bernard Zinman
Journal: Diabetes Care
Diabetes Care 2024;47(11):2017–2023
https://doi.org/10.2337/dc24-1375
Published: 20 September 2024
View article titled, A Glycemic Threshold Above Which the Improvement of β-Cell Function and Glycemia in Response to Insulin Therapy Is Amplified in Early Type 2 Diabetes: The Reversal of Glucotoxicity
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Journal Articles

Dulaglutide and Kidney Function–Related Outcomes in Type 2 Diabetes: A REWIND Post Hoc Analysis

Free
Fady T. Botros, Hertzel C. Gerstein, Raleigh Malik, Claudia Nicolay, Anastasia Hoover, Ibrahim Turfanda, Helen M. Colhoun, Jonathan E. Shaw
Journal: Diabetes Care
Diabetes Care 2023;46(8):1524–1530
https://doi.org/10.2337/dc23-0231
Published: 21 June 2023
View article titled, Dulaglutide and Kidney Function–Related Outcomes in Type 2 Diabetes: A REWIND Post Hoc Analysis
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Journal Articles

Biomarker Changes Associated With Both Dulaglutide and Cardiovascular Events in the REWIND Randomized Controlled Trial: A Nested Case-Control Post Hoc Analysis

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Hertzel C. Gerstein, Shun-Fu Lee, Guillaume Paré, M. Angelyn Bethel, Helen M. Colhoun, Anastasia Hoover, Mark Lakshmanan, Yanzhu Lin, Valentina Pirro, Hui-Rong Qian, Giacomo Ruotolo, Lars Ryden, Jonathan M. Wilson, Kevin L. Duffin
Journal: Diabetes Care
Diabetes Care 2023;46(5):1046–1051
https://doi.org/10.2337/dc22-2397
Published: 10 March 2023
View article titled, Biomarker Changes Associated With Both Dulaglutide and Cardiovascular Events in the REWIND Randomized Controlled Trial: A Nested Case-Control Post Hoc Analysis
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Journal Articles

Dulaglutide and a Composite Outcome Reflecting Atherosclerosis in the REWIND Trial: A Post Hoc Analysis

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Giulia Ferrannini, Linda G. Mellbin, Faith Kirabo, Chinthanie Ramasundarahettige, Hertzel C. Gerstein, Lars Rydén
Journal: Diabetes Care
Diabetes Care 2022;45(10):e146–e147
https://doi.org/10.2337/dc22-0903
Published: 30 August 2022
View article titled, Dulaglutide and a Composite Outcome Reflecting Atherosclerosis in the REWIND Trial: A Post Hoc Analysis
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Journal Articles

Protein Biomarkers and Cardiovascular Outcomes in People With Type 2 Diabetes and Acute Coronary Syndrome: The ELIXA Biomarker Study

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Hertzel C. Gerstein, Sibylle Hess, Brian Claggett, Kenneth Dickstein, Lars Kober, Aldo P. Maggioni, John J.V. McMurray, Jeffrey L. Probstfield, Matthew C. Riddle, Jean-Claude Tardif, Marc A. Pfeffer
Journal: Diabetes Care
Diabetes Care 2022;45(9):2152–2155
https://doi.org/10.2337/dc22-0453
Published: 11 July 2022
View article titled, Protein Biomarkers and Cardiovascular Outcomes in People With Type 2 Diabetes and Acute Coronary Syndrome: The ELIXA Biomarker Study
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Journal Articles

Glucose Intolerance in Pregnancy and Offspring Obesity in Late Adolescence

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Cole D. Bendor, Aya Bardugo, Ran Shmuel Rotem, Estela Derazne, Hertzel C. Gerstein, Dorit Tzur, Orit Pinhas-Hamiel, Avishai M. Tsur, Tali Cukierman-Yaffe, Yael Lebenthal, Arnon Afek, Gabriel Chodick, Gilad Twig
Journal: Diabetes Care
Diabetes Care 2022;45(7):1540–1548
https://doi.org/10.2337/dc21-2634
Published: 04 June 2022
View article titled, Glucose Intolerance in Pregnancy and Offspring Obesity in Late Adolescence
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Journal Articles

Response to Comment on Koska et al. Advanced Glycation End Products Predict Loss of Renal Function and High-Risk Chronic Kidney Disease in Type 2 Diabetes. Diabetes Care 2022;44:684–691

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Juraj Koska, Hertzel C. Gerstein, Paul J. Beisswenger, Peter D. Reaven
Journal: Diabetes Care
Diabetes Care 2022;45(6):e111–e112
https://doi.org/10.2337/dci22-0013
Published: 27 May 2022
View article titled, Response to Comment on Koska et al. Advanced Glycation End Products Predict Loss of Renal Function and High-Risk Chronic Kidney Disease in Type 2 Diabetes. Diabetes Care 2022;44:684–691
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Journal Articles

Advanced Glycation End Products Predict Loss of Renal Function and High-Risk Chronic Kidney Disease in Type 2 Diabetes

Free
Juraj Koska, Hertzel C. Gerstein, Paul J. Beisswenger, Peter D. Reaven
Journal: Diabetes Care
Diabetes Care 2022;45(3):684–691
https://doi.org/10.2337/dc21-2196
Published: 20 January 2022
View article titled, Advanced Glycation End Products Predict Loss of Renal Function and High-Risk Chronic Kidney Disease in Type 2 Diabetes
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Journal Articles

HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial

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Anita Y.M. Kwan, Hertzel C. Gerstein, Jan Basile, Denis Xavier, Juan M. Maldonado, Sohini Raha, Manige Konig
Journal: Diabetes Care
Diabetes Care 2022;45(3):547–554
https://doi.org/10.2337/dc21-1160
Published: 18 January 2022
View article titled, HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial
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Journal Articles

Remission of Type 2 Diabetes Following a Short-term Intensive Intervention With Insulin Glargine, Sitagliptin, and Metformin: Results of an Open-label Randomized Parallel-Design Trial

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Natalia McInnes, Stephanie Hall, Irene Hramiak, Ronald J. Sigal, Ronald Goldenberg, Nikhil Gupta, Remi Rabasa-Lhoret, Manoela Braga, Vincent Woo, Farah Sultan, Rose Otto, Ada Smith, Diana Sherifali, Yan Yun Liu, Hertzel C. Gerstein
Journal: Diabetes Care
Diabetes Care 2022;45(1):178–185
https://doi.org/10.2337/dc21-0278
Published: 02 November 2021
View article titled, Remission of Type 2 Diabetes Following a Short-term Intensive Intervention With Insulin Glargine, Sitagliptin, and Metformin: Results of an Open-label Randomized Parallel-Design Trial
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Journal Articles

Lingering Effects of Hyperglycemia in Recently Diagnosed Diabetes During Long-term Follow-up of the DCCT/EDIC and UKPDS Cohorts: More Evidence That Early Control Matters

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Matthew C. Riddle, Hertzel C. Gerstein, Philip D. Home
Journal: Diabetes Care
Diabetes Care 2021;44(10):2212–2215
https://doi.org/10.2337/dci21-0030
Published: 30 September 2021
View article titled, Lingering Effects of Hyperglycemia in Recently Diagnosed Diabetes During Long-term Follow-up of the DCCT/EDIC and UKPDS Cohorts: More Evidence That Early Control Matters
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Journal Articles

Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes

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Matthew C. Riddle, William T. Cefalu, Philip H. Evans, Hertzel C. Gerstein, Michael A. Nauck, William K. Oh, Amy E. Rothberg, Carel W. le Roux, Francesco Rubino, Philip Schauer, Roy Taylor, Douglas Twenefour
Journal: Diabetes Care
Diabetes Care 2021;44(10):2438–2444
https://doi.org/10.2337/dci21-0034
Published: 30 August 2021
View article titled, Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes
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Journal Articles

Creating Composite Indices From Continuous Variables for Research: The Geometric Mean

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Hertzel C. Gerstein, Chinthanie Ramasundarahettige, Shrikant I. Bangdiwala
Journal: Diabetes Care
Diabetes Care 2021;44(5):e85–e86
https://doi.org/10.2337/dc20-2446
Published: 25 February 2021
View article titled, Creating Composite Indices From Continuous Variables for Research: The Geometric Mean
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Journal Articles

HbA1c Change and Diabetic Retinopathy During GLP-1 Receptor Agonist Cardiovascular Outcome Trials: A Meta-analysis and Meta-regression

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M. Angelyn Bethel, Rafael Diaz, Noelia Castellana, Indranil Bhattacharya, Hertzel C. Gerstein, Mark C. Lakshmanan
Journal: Diabetes Care
Diabetes Care 2021;44(1):290–296
https://doi.org/10.2337/dc20-1815
Published: 14 December 2020
View article titled, HbA1c Change and Diabetic Retinopathy During GLP-1 Receptor Agonist Cardiovascular Outcome Trials: A Meta-analysis and Meta-regression
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Journal Articles

Adolescent Hypertension and Risk for Early-Onset Type 2 Diabetes: A Nationwide Study of 1.9 Million Israeli Adolescents

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Boris Fishman, Ehud Grossman, Inbar Zucker, Omri Orr, Miri Lutski, Aya Bardugo, Cole D. Bendor, Yoav Leiba, Tali Cukierman-Yaffe, Estela Derazne, Ofri Mosenzon, Dorit Tzur, Zivan Beer, Orit Pinhas-Hamiel, Tamar Fishman, Arnon Afek, Amir Tirosh, Itamar Raz, Hertzel C. Gerstein, Gilad Twig
Journal: Diabetes Care
Diabetes Care 2021;44(1):e6–e8
https://doi.org/10.2337/dc20-1752
Published: 04 November 2020
View article titled, Adolescent Hypertension and Risk for Early-Onset Type 2 Diabetes: A Nationwide Study of 1.9 Million Israeli Adolescents
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Journal Articles

Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial

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Yaling Tang, Hetal Shah, Carlos Roberto Bueno Junior, Xiuqin Sun, Joanna Mitri, Maria Sambataro, Luisa Sambado, Hertzel C. Gerstein, Vivian Fonseca, Alessandro Doria, Rodica Pop-Busui
Journal: Diabetes Care
Diabetes Care 2021;44(1):164–173
https://doi.org/10.2337/dc20-1842
Published: 03 November 2020
View article titled, Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial
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