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M. Angelyn Bethel
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Journal Articles

Biomarker Changes Associated With Both Dulaglutide and Cardiovascular Events in the REWIND Randomized Controlled Trial: A Nested Case-Control Post Hoc Analysis

Hertzel C. Gerstein, Shun-Fu Lee, Guillaume Paré, M. Angelyn Bethel, Helen M. Colhoun, Anastasia Hoover, Mark Lakshmanan, Yanzhu Lin, Valentina Pirro, Hui-Rong Qian, Giacomo Ruotolo, Lars Ryden, Jonathan M. Wilson, Kevin L. Duffin
Journal: Diabetes Care
Diabetes Care 2023;46(5):1046–1051
https://doi.org/10.2337/dc22-2397
Published: 10 March 2023
View article titled, Biomarker Changes Associated With Both Dulaglutide and Cardiovascular Events in the REWIND Randomized Controlled Trial: A Nested Case-Control Post Hoc Analysis
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Journal Articles

Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)

Juan P. Frias, Enzo Bonora, Luis Nevarez Ruiz, Ying G. Li, Zhuoxin Yu, Zvonko Milicevic, Raleigh Malik, M. Angelyn Bethel, David A. Cox
Journal: Diabetes Care
Diabetes Care 2021;44(3):765–773
https://doi.org/10.2337/dc20-1473
Published: 04 January 2021
View article titled, Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
Open the PDF for Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11) in another window
Journal Articles

Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL

Eberhard Standl, Susanna R. Stevens, Yuliya Lokhnygina, M. Angelyn Bethel, John B. Buse, Stephanie M. Gustavson, Aldo P. Maggioni, Robert J. Mentz, Adrian F. Hernandez, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2020;43(3):643–652
https://doi.org/10.2337/dc19-1079
Published: 27 December 2020
View article titled, Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL
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Includes: Supplementary data
Journal Articles

HbA1c Change and Diabetic Retinopathy During GLP-1 Receptor Agonist Cardiovascular Outcome Trials: A Meta-analysis and Meta-regression

M. Angelyn Bethel, Rafael Diaz, Noelia Castellana, Indranil Bhattacharya, Hertzel C. Gerstein, Mark C. Lakshmanan
Journal: Diabetes Care
Diabetes Care 2021;44(1):290–296
https://doi.org/10.2337/dc20-1815
Published: 14 December 2020
View article titled, HbA<sub>1c</sub> Change and Diabetic Retinopathy During GLP-1 Receptor Agonist Cardiovascular Outcome Trials: A Meta-analysis and Meta-regression
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Journal Articles

Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

Shelby D. Reed, Yanhong Li, Helen A. Dakin, Frauke Becker, Jose Leal, Stephanie M. Gustavson, Bernt Kartman, Eric Wittbrodt, Robert J. Mentz, Neha J. Pagidipati, M. Angelyn Bethel, Alastair M. Gray, Rury R. Holman, Adrian F. Hernandez
Journal: Diabetes Care
Diabetes Care 2020;43(2):374–381
https://doi.org/10.2337/dc19-0950
Published: 05 December 2019
View article titled, Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)
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Includes: Supplementary data
Journal Articles

Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial

M. Angelyn Bethel, Robert J. Mentz, Peter Merrill, John B. Buse, Juliana C. Chan, Shaun G. Goodman, Nayyar Iqbal, Neli Jakuboniene, Brian Katona, Yuliya Lokhnygina, Renato D. Lopes, Aldo P. Maggioni, Peter Ohman, Tsvetalina Tankova, George L. Bakris, Adrian F. Hernandez, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2020;43(2):446–452
https://doi.org/10.2337/dc19-1065
Published: 22 November 2019
View article titled, Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial
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Includes: Supplementary data
Journal Articles

Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL)

M. Angelyn Bethel, Rishi A. Patel, Vivian P. Thompson, Peter Merrill, Shelby D. Reed, Yanhong Li, Sara Ahmadi, Brian G. Katona, Stephanie M. Gustavson, Peter Ohman, Nayyar Iqbal, Robert F. Gagel, Adrian F. Hernandez, John B. Buse, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2019;42(6):1075–1080
https://doi.org/10.2337/dc18-2028
Published: 22 April 2019
View article titled, Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL)
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Includes: Supplementary data
Journal Articles

Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

M. Angelyn Bethel, Samuel S. Engel, Jennifer B. Green, Zhen Huang, Robert G. Josse, Keith D. Kaufman, Eberhard Standl, Shailaja Suryawanshi, Frans Van de Werf, Darren K. McGuire, Eric D. Peterson, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2017;40(4):494–501
https://doi.org/10.2337/dc16-1135
Published: 05 January 2017
View article titled, Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)
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Includes: Supplementary data
Journal Articles

Pancreatic Safety of Sitagliptin in the TECOS Study

John B. Buse, M. Angelyn Bethel, Jennifer B. Green, Susanna R. Stevens, Yuliya Lokhnygina, Pablo Aschner, Carlos Raffo Grado, Tsvetalina Tankova, Julio Wainstein, Robert Josse, John M. Lachin, Samuel S. Engel, Keyur Patel, Eric D. Peterson, Rury R. Holman
Journal: Diabetes Care
Diabetes Care 2017;40(2):164–170
https://doi.org/10.2337/dc15-2780
Published: 14 September 2016
View article titled, Pancreatic Safety of Sitagliptin in the TECOS Study
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Includes: Supplementary data
Journal Articles

Evaluation of a Self-Administered Oral Glucose Tolerance Test

M. Angelyn Bethel, MD, Hermione C. Price, MRCP, Harald Sourij, MD, Sarah White, RGN, Ruth L. Coleman, MSC, Arne Ring, PHD, Irene E.C. Kennedy, PHD, Lynne Tucker, BSC, Rury R. Holman, FRCP
Journal: Diabetes Care
Diabetes Care 2013;36(6):1483–1488
https://doi.org/10.2337/dc12-0643
Published: 15 May 2013
View article titled, Evaluation of a Self-Administered Oral Glucose Tolerance Test
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Includes: Supplementary data
Journal Articles

Costs of the Metabolic Syndrome in Elderly Individuals: Findings from the Cardiovascular Health Study

Lesley H. Curtis, PHD, Bradley G. Hammill, MS, M. Angelyn Bethel, MD, Kevin J. Anstrom, PHD, John S. Gottdiener, MD, Kevin A. Schulman, MD
Journal: Diabetes Care
Diabetes Care 2007;30(10):2553–2558
https://doi.org/10.2337/dc07-0460
Published: 01 October 2007
View article titled, Costs of the Metabolic Syndrome in Elderly Individuals: <subtitle>Findings from the Cardiovascular Health Study</subtitle>
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Journal Articles

Modification of Postprandial Hyperglycemia With Insulin Lispro Improves Glucose Control in Patients With Type 2 Diabetes

Mary N Feinglos, MD, CM, Connie H Thacker, BA, CCRA, Jennifer English, RN, BSN, M Angelyn Bethel, BS, James D Lane, PHD
Journal: Diabetes Care
Diabetes Care 1997;20(10):1539–1542
https://doi.org/10.2337/diacare.20.10.1539
Published: 01 October 1997
View article titled, Modification of Postprandial Hyperglycemia With Insulin Lispro Improves Glucose Control in Patients With Type 2 Diabetes
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