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Journal Articles

Exocrine Proteins Including Trypsin(ogen) as a Key Biomarker in Type 1 Diabetes

Lilianna Bakinowska, Tanwi Vartak, Thato Phuthego, Michelle Taylor, Kyla Chandler, Samual T. Jerram, Steven Williams, Marc Feldmann, Desmond G. Johnson, Kashyap A. Patel, Alistair J.K. Williams, Anna E. Long, R. David Leslie, Kathleen M. Gillespie, the Action LADA Consortium, Richard David Leslie, Mohammed I Hawa, Paolo Pozzilli, Henning Beck-Nielsen, Knud Yderstraede, Steven Hunter, David Hadden, Raffaella Buzzetti, Werner Scherbaum, Hubert Kolb, Nanette C. Schloot, Jochen Seissler, Guntram Schernthaner, MD, Jaakko Tuomilehto, Cinzia Sarti, Alberto De Leiva, Eulalia Brugues, Didac Mauricio, Charles Thivolet, the BOX Study Group, Isabel Wilson, Rachel Aitken, Clare Megson, Chitrabhanu Ballav, Atanu Dutta, Michelle Russell-Taylor, Rachel Besser, James Bursell, Shanthi Chandran, Sejal Patel, Anne Smith, Manohara Kenchaiah, Gomathi Margabanthu, Foteini Kavvoura, Chandan Yaliwal
Journal: Diabetes Care
Diabetes Care 2023;46(4):714–721
https://doi.org/10.2337/dc22-1317
Published: 26 January 2023
View article titled, Exocrine Proteins Including Trypsin(ogen) as a Key Biomarker in Type 1 Diabetes
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Journal Articles

Computed Tomography Highlights Increased Visceral Adiposity Associated With Critical Illness in COVID-19

Sofia Battisti, Claudio Pedone, Nicola Napoli, Emanuele Russo, Vanni Agnoletti, Stefano Geniere Nigra, Caterina Dengo, Martina Mughetti, Caterina Conte, Paolo Pozzilli, Emanuela Giampalma, Rocky Strollo
Journal: Diabetes Care
Diabetes Care 2020;43(10):e129–e130
https://doi.org/10.2337/dc20-1333
Published: 11 September 2020
View article titled, Computed Tomography Highlights Increased Visceral Adiposity Associated With Critical Illness in COVID-19
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Journal Articles

Comment on So et al. Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody–Positive Individuals. Diabetes Care 2020;43:913–917

Ghadeer E. Alhamar, Rocky Strollo, Paolo Pozzilli
Journal: Diabetes Care
Diabetes Care 2020;43(8):e102
https://doi.org/10.2337/dc20-0409
Published: 10 July 2020
View article titled, Comment on So et al. Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody–Positive Individuals. Diabetes Care 2020;43:913–917
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Journal Articles

Effects of COVID-19 Lockdown on Glucose Control: Continuous Glucose Monitoring Data From People With Diabetes on Intensive Insulin Therapy

Ernesto Maddaloni, Lucia Coraggio, Silvia Pieralice, Angela Carlone, Paolo Pozzilli, Raffaella Buzzetti
Journal: Diabetes Care
Diabetes Care 2020;43(8):e86–e87
https://doi.org/10.2337/dc20-0954
Published: 05 June 2020
View article titled, Effects of COVID-19 Lockdown on Glucose Control: Continuous Glucose Monitoring Data From People With Diabetes on Intensive Insulin Therapy
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Journal Articles

Inverse Relationship Between Organ-Specific Autoantibodies and Systemic Immune Mediators in Type 1 Diabetes and Type 2 Diabetes: Action LADA 11

Nanette C. Schloot, Minh N. Pham, Mohammed I. Hawa, Paolo Pozzilli, Werner A. Scherbaum, Matthias Schott, Hubert Kolb, Steven Hunter, Guntram Schernthaner, Charles Thivolet, Jochen Seissler, Richard David Leslie, for the Action LADA Group
Journal: Diabetes Care
Diabetes Care 2016;39(11):1932–1939
https://doi.org/10.2337/dc16-0293
Published: 29 August 2016
View article titled, Inverse Relationship Between Organ-Specific Autoantibodies and Systemic Immune Mediators in Type 1 Diabetes and Type 2 Diabetes: Action LADA 11
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Includes: Supplementary data
Journal Articles

Detection of Insulitis by Pancreatic Scintigraphy With 99mTc-Labeled IL-2 and MRI in Patients With LADA (Action LADA 10)

Alberto Signore, Gabriela Capriotti, Marco Chianelli, Elena Bonanno, Filippo Galli, Carlo Catalano, Ana M. Quintero, Giorgio De Toma, Silvia Manfrini, Paolo Pozzilli, the Action LADA Group
Journal: Diabetes Care
Diabetes Care 2015;38(4):652–658
https://doi.org/10.2337/dc14-0580
Published: 09 February 2015
View article titled, Detection of Insulitis by Pancreatic Scintigraphy With <sup>99m</sup>Tc-Labeled IL-2 and MRI in Patients With LADA (Action LADA 10)
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Journal Articles

Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial. Diabetes Care 2014;37: 1392–1400 . DOI: 10.2337/dc13-1391

Itamar Raz, Anette G. Ziegler, Thomas Linn, Guntram Schernthaner, Francois Bonnici, Larry A. Distiller, Carla Giordano, Francesco Giorgino, Liat de Vries, Didac Mauricio, Vlastimil Procházka, Julio Wainstein, Dana Elias, Ann Avron, Merana Tamir, Rachel Eren, Dana Peled, Shlomo Dagan, Irun R. Cohen, Paolo Pozzilli, the DIA-AID 1 Writing Group
Journal: Diabetes Care
Diabetes Care 2015;38(1):178
https://doi.org/10.2337/dc15-rt01
Published: 13 December 2014
View article titled, Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial. Diabetes Care 2014;37: 1392–1400 . DOI: 10.2337/dc13-1391
Open the PDF for Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial. Diabetes Care 2014;37: 1392–1400 . DOI: 10.2337/dc13-1391 in another window
Journal Articles

Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal. Diabetes Care 2014;37: 1384–1391 . DOI: 10.2337/dc13-1392

Paolo Pozzilli, Itamar Raz, Dana Peled, Dana Elias, Ann Avron, Merana Tamir, Rachel Eren, Shlomo Dagan, Irun R. Cohen
Journal: Diabetes Care
Diabetes Care 2015;38(1):179
https://doi.org/10.2337/dc15-rt01a
Published: 13 December 2014
View article titled, Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal. Diabetes Care 2014;37: 1384–1391 . DOI: 10.2337/dc13-1392
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Journal Articles

Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes

Ronnie Aronson, Peter A. Gottlieb, Jens S. Christiansen, Thomas W. Donner, Emanuele Bosi, Bruce W. Bode, Paolo Pozzilli, the DEFEND Investigator Group
Journal: Diabetes Care
Diabetes Care 2014;37(10):2746–2754
https://doi.org/10.2337/dc13-0327
Published: 10 September 2014
View article titled, Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal

Paolo Pozzilli, Itamar Raz, Dana Peled, Dana Elias, Ann Avron, Merana Tamir, Rachel Eren, Shlomo Dagan, Irun R. Cohen
Journal: Diabetes Care
Diabetes Care 2014;37(5):1384–1391
https://doi.org/10.2337/dc13-1392
Published: 10 April 2014
View article titled, Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal
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Includes: Supplementary data
Journal Articles

Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial

Itamar Raz, Anette G. Ziegler, Thomas Linn, Guntram Schernthaner, Francois Bonnici, Larry A. Distiller, Carla Giordano, Francesco Giorgino, Liat de Vries, Didac Mauricio, Vlastimil Procházka, Julio Wainstein, Dana Elias, Ann Avron, Merana Tamir, Rachel Eren, Dana Peled, Shlomo Dagan, Irun R. Cohen, Paolo Pozzilli, the DIA-AID 1 Writing Group
Journal: Diabetes Care
Diabetes Care 2014;37(5):1392–1400
https://doi.org/10.2337/dc13-1391
Published: 10 April 2014
View article titled, Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial
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Includes: Supplementary data
Journal Articles

Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical Phenotype: Action LADA 7. Diabetes Care 2013;36: 908–913

Mohammed I. Hawa, Hubert Kolb, Nanette Schloot, Huriya Beyan, Stavroula A. Paschou, Raffaella Buzzetti, Didac Mauricio, Alberto De Leiva, Knud Yderstraede, Henning Beck-Neilsen, Jaakko Tuomilehto, Cinzia Sarti, Charles Thivolet, David Hadden, Steven Hunter, Guntram Schernthaner, Werner A. Scherbaum, Rhys Williams, Sinead Brophy, Paolo Pozzilli, Richard David Leslie, on behalf of the Action LADA Consortium
Journal: Diabetes Care
Diabetes Care 2014;37(5):1494
https://doi.org/10.2337/dc14-er05
Published: 10 April 2014
View article titled, Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical Phenotype: Action LADA 7. Diabetes Care 2013;36: 908–913
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Journal Articles

Is Glucose Control Important for Prevention of Cardiovascular Disease in Diabetes?

Edoardo Mannucci, MD, Ilaria Dicembrini, MD, Angelo Lauria, MD, Paolo Pozzilli, MD
Journal: Diabetes Care
Diabetes Care 2013;36(Supplement_2):S259–S263
https://doi.org/10.2337/dcS13-2018
Published: 17 July 2013
View article titled, Is Glucose Control Important for Prevention of Cardiovascular Disease in Diabetes?
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Journal Articles

Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical Phenotype: Action LADA 7

Mohammed I. Hawa, PHD, Hubert Kolb, MD, Nanette Schloot, MD, Huriya Beyan, PHD, Stavroula A. Paschou, PHD, Raffaella Buzzetti, MD, Didac Mauricio, MD, Alberto De Leiva, MD, Knud Yderstraede, MD, Henning Beck-Neilsen, MD, Jaakko Tuomilehto, MD, Cinzia Sarti, MD, Charles Thivolet, MD, David Hadden, MD, Steven Hunter, MD, Guntram Schernthaner, MD, Werner A. Scherbaum, MD, Rhys Williams, MD, Sinead Brophy, MD, Paolo Pozzilli, MD, Richard David Leslie, MD, on behalf of the Action LADA consortium
Journal: Diabetes Care
Diabetes Care 2013;36(4):908–913
https://doi.org/10.2337/dc12-0931
Published: 14 March 2013
View article titled, Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical Phenotype: <subtitle>Action LADA 7</subtitle>
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Includes: Supplementary data
Journal Articles

Breast-Feeding and Childhood-Onset Type 1 Diabetes: A pooled analysis of individual participant data from 43 observational studies

Chris R. Cardwell, PHD, Lars C. Stene, PHD, Johnny Ludvigsson, MD, Joachim Rosenbauer, MD, Ondrej Cinek, MD, Jannet Svensson, PHD, Francisco Perez-Bravo, PHD, Anjum Memon, MBBS, Suely G. Gimeno, DPH, Emma J.K. Wadsworth, PHD, Elsa S. Strotmeyer, PHD, Michael J. Goldacre, FFPHM, Katja Radon, PHD, Lee-Ming Chuang, MD, Roger C. Parslow, PHD, Amanda Chetwynd, PHD, Kyriaki Karavanaki, MD, Girts Brigis, MD, Paolo Pozzilli, MBBS, Brone UrbonaitĖ, MD, Edith Schober, MD, Gabriele Devoti, MD, Sandra Sipetic, MD, Geir Joner, MD, Constantin Ionescu-Tirgoviste, MD, Carine E. de Beaufort, MD, Kirsten Harrild, MSC, Victoria Benson, PHD, Erkki Savilahti, MD, Anne-Louise Ponsonby, MBBS, Mona Salem, MD, Samira Rabiei, MSC, Chris C. Patterson, PHD
Journal: Diabetes Care
Diabetes Care 2012;35(11):2215–2225
https://doi.org/10.2337/dc12-0438
Published: 13 October 2012
View article titled, Breast-Feeding and Childhood-Onset Type 1 Diabetes: <subtitle>A pooled analysis of individual participant data from 43 observational studies</subtitle>
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Includes: Supplementary data
Journal Articles

Diabetes-Related Autoantibodies in Children With Acute Lymphoblastic Leukemia

Carla Bizzarri, MD, Rita M. Pinto, MD, Dario Pitocco, MD, Elisa Astorri, MD, PHD, Marco Cappa, MD, Mohammed Hawa, MD, Germana Giannone, MD, Andrea Palermo, MD, Ernesto Maddaloni, MD, David R.G. Leslie, MD, Paolo Pozzilli, MD, on behalf of the IMDIAB Group
Journal: Diabetes Care
Diabetes Care 2012;35(3):e23
https://doi.org/10.2337/dc11-1946
Published: 10 February 2012
View article titled, Diabetes-Related Autoantibodies in Children With Acute Lymphoblastic Leukemia
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Journal Articles

Obesity, Autoimmunity, and Double Diabetes in Youth

Paolo Pozzilli, MD, Chiara Guglielmi, MD, Sonia Caprio, MD, Raffaella Buzzetti, MD
Journal: Diabetes Care
Diabetes Care 2011;34(Supplement_2):S166–S170
https://doi.org/10.2337/dc11-s213
Published: 22 April 2011
View article titled, Obesity, Autoimmunity, and Double Diabetes in Youth
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Journal Articles

Incidence of Type 1 Diabetes Has Doubled in Rome and the Lazio Region in the 0- to 14-Year Age-Group: A 6-Year Prospective Study (2004–2009)

Carla Bizzarri, MD, Patrizia Ippolita Patera, MD, Claudia Arnaldi, MD, Stefano Petrucci, MD, Maria Luisa Manca Bitti, MD, Raffaella Scrocca, MD, Silvia Manfrini, MD, Rosalba Portuesi, MD, Raffaella Buzzetti, MD, Marco Cappa, MD, Paolo Pozzilli, MD, the Immunotherapy Diabetes (IMDIAB) Group
Journal: Diabetes Care
Diabetes Care 2010;33(11):e140
https://doi.org/10.2337/dc10-1168
Published: 01 November 2010
View article titled, Incidence of Type 1 Diabetes Has Doubled in Rome and the Lazio Region in the 0- to 14-Year Age-Group: A 6-Year Prospective Study (2004–2009)
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Includes: Supplementary data
Journal Articles

No Protective Effect of Calcitriol on β-Cell Function in Recent-Onset Type 1 Diabetes: The IMDIAB XIII trial

Carla Bizzarri, MD, Dario Pitocco, MD, Nicola Napoli, MD, Enrico Di Stasio, MD, Daria Maggi, MD, Silvia Manfrini, MD, Concetta Suraci, MD, Maria Gisella Cavallo, MD, Marco Cappa, MD, Giovanni Ghirlanda, MD, Paolo Pozzilli, MD, the IMDIAB Group
Journal: Diabetes Care
Diabetes Care 2010;33(9):1962–1963
https://doi.org/10.2337/dc10-0814
Published: 01 September 2010
View article titled, No Protective Effect of Calcitriol on β-Cell Function in Recent-Onset Type 1 Diabetes: <subtitle>The IMDIAB XIII trial</subtitle>
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Journal Articles

β-Cell Protection and Therapy for Latent Autoimmune Diabetes in Adults

Simona Cernea, MD, Raffaella Buzzetti, MD, Paolo Pozzilli, MD
Journal: Diabetes Care
Diabetes Care 2009;32(suppl_2):S246–S252
https://doi.org/10.2337/dc09-S317
Published: 01 November 2009
View article titled, β-Cell Protection and Therapy for Latent Autoimmune Diabetes in Adults
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