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Journal Articles

Prediction of Diabetes Based on Baseline Metabolic Characteristics in Individuals at High Risk

Ralph A. DeFronzo, MD, Devjit Tripathy, MD, Dawn C. Schwenke, PHD, MaryAnn Banerji, MD, George A. Bray, MD, Thomas A. Buchanan, MD, Stephen C. Clement, MD, Robert R. Henry, MD, Abbas E. Kitabchi, PHD, Sunder Mudaliar, MD, Robert E. Ratner, MD, Frankie B. Stentz, MS, Nicolas Musi, MD, Peter D. Reaven, MD, Amalia Gastaldelli, PHD, for the ACT NOW Study

Diabetes Care 2013;36(11):3607–3612

DOI: https://doi.org/10.2337/dc13-0520

Published: 15 October 2013

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Journal Articles

Characterization of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and Subjects With Type 2 Diabetes

Ralph A. DeFronzo, MD, Marcus Hompesch, MD, Sreeneeranj Kasichayanula, PHD, Xiaoni Liu, PHD, Ying Hong, PHD, Marc Pfister, MD, Linda A. Morrow, MD, Bruce R. Leslie, MD, David W. Boulton, MD, Agatha Ching, PHD, Frank P. LaCreta, PHD, Steven C. Griffen, MD

Diabetes Care 2013;36(10):3169–3176

DOI: https://doi.org/10.2337/dc13-0387

Published: 14 September 2013

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Includes: Supplementary data

Journal Articles

Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study

Carolina Solis-Herrera, MD, Curtis Triplitt, PHARMD, Jose de Jesús Garduno-Garcia, MD, John Adams, BS, Ralph A. DeFronzo, MD, Eugenio Cersosimo, MD

Diabetes Care 2013;36(9):2756–2762

DOI: https://doi.org/10.2337/dc12-2072

Published: 13 August 2013

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Includes: Supplementary data

Journal Articles

In Vivo Actions of Peroxisome Proliferator–Activated Receptors: Glycemic control, insulin sensitivity, and insulin secretion

Roy Eldor, MD, Ralph A. DeFronzo, MD, Muhammad Abdul-Ghani, MD

Diabetes Care 2013;36(Supplement_2):S162–S174

DOI: https://doi.org/10.2337/dcS13-2003

Published: 17 July 2013

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Journal Articles

Pathophysiologic Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes

Ralph A. DeFronzo, MD, Roy Eldor, MD, Muhammad Abdul-Ghani, MD

Diabetes Care 2013;36(Supplement_2):S127–S138

DOI: https://doi.org/10.2337/dcS13-2011

Published: 17 July 2013

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Journal Articles

Is Incretin-Based Therapy Ready for the Care of Hospitalized Patients With Type 2 Diabetes?: The time has come for GLP-1 receptor agonists!

Stanley Schwartz, MD, FACP, FACE, Ralph A. DeFronzo, MD

Diabetes Care 2013;36(7):2107–2111

DOI: https://doi.org/10.2337/dc12-2060

Published: 12 June 2013

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Journal Articles

Two-Step Approach for the Prediction of Future Type 2 Diabetes Risk

Muhammad A. Abdul-Ghani, MD, Tamam Abdul-Ghani, MSC, Michael P. Stern, MD, Jasmina Karavic, Tiinamaija Tuomi, MD, Insoma Bo, MD, Ralph A. DeFronzo, MD, Leif Groop, MD

Diabetes Care 2011;34(9):2108–2112

DOI: https://doi.org/10.2337/dc10-2201

Published: 19 August 2011

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Journal Articles

Type 2 Diabetes Can Be Prevented With Early Pharmacological Intervention

Ralph A. DeFronzo, MD, Muhammad Abdul-Ghani, MD

Diabetes Care 2011;34(Supplement_2):S202–S209

DOI: https://doi.org/10.2337/dc11-s221

Published: 22 April 2011

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Includes: Supplementary data

Journal Articles

The Relationship Between β-Cell Function and Glycated Hemoglobin: Results from the Veterans Administration Genetic Epidemiology Study

Mustafa Kanat, MD, Diedre Winnier, PHD, Luke Norton, PHD, Nazik Arar, MD, Chris Jenkinson, PHD, Ralph A. DeFronzo, MD, Muhammad A. Abdul-Ghani, MD

Diabetes Care 2011;34(4):1006–1010

DOI: https://doi.org/10.2337/dc10-1352

Published: 21 March 2011

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Journal Articles

Bromocriptine: A Sympatholytic, D2-Dopamine Agonist for the Treatment of Type 2 Diabetes

Ralph A. DeFronzo, MD

Diabetes Care 2011;34(4):789–794

DOI: https://doi.org/10.2337/dc11-0064

Published: 21 March 2011

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Includes: Supplementary data

Journal Articles

Reduced Time Points to Calculate the Composite Index

Ralph A. DeFronzo, MD, Masafumi Matsuda, MD, PHD

Diabetes Care 2010;33(7):e93

DOI: https://doi.org/10.2337/dc10-0646

Published: 01 July 2010

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Journal Articles

Effects of Exenatide Plus Rosiglitazone on β-Cell Function and Insulin Sensitivity in Subjects With Type 2 Diabetes on Metformin

Ralph A. DeFronzo, MD, Curtis Triplitt, PHARMD, Yongming Qu, PHD, Michelle S. Lewis, PHD, David Maggs, MD, Leonard C. Glass, MD

Diabetes Care 2010;33(5):951–957

DOI: https://doi.org/10.2337/dc09-1521

Published: 27 January 2010

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Includes: Supplementary data

Journal Articles

Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose

Muhammad A. Abdul-Ghani, MD, PHD, Michael P. Stern, MD, Valeriya Lyssenko, MD, PHD, Tiinamaija Tuomi, MD, PHD, Leif Groop, MD, Ralph A. DeFronzo, MD

Diabetes Care 2010;33(3):557–561

DOI: https://doi.org/10.2337/dc09-1145

Published: 10 December 2009

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Journal Articles

Plasma Glucose Concentration and Prediction of Future Risk of Type 2 Diabetes

Muhammad A. Abdul-Ghani, MD, PHD, Ralph A. DeFronzo, MD

Diabetes Care 2009;32(suppl_2):S194–S198

DOI: https://doi.org/10.2337/dc09-S309

Published: 01 November 2009

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Journal Articles

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

Ralph A. DeFronzo, MD, Devjit Tripathy, MD

Diabetes Care 2009;32(suppl_2):S157–S163

DOI: https://doi.org/10.2337/dc09-S302

Published: 01 November 2009

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Includes: Supplementary data

Journal Articles

Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels: Response to Utzschneider et al.

Ralph A. DeFronzo, MD, Muhammad A. Abdul-Ghani, MD

Diabetes Care 2009;32(7):e86

DOI: https://doi.org/10.2337/dc09-0537

Published: 01 July 2009

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Journal Articles

Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance

Alberto O. Chavez, MD, Marjorie Molina-Carrion, MD, Muhammad A. Abdul-Ghani, MD, PHD, Franco Folli, MD, PHD, Ralph A. DeFronzo, MD, Devjit Tripathy, MD, PHD

Diabetes Care 2009;32(8):1542–1546

DOI: https://doi.org/10.2337/dc09-0684

Published: 01 June 2009

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Journal Articles

The Efficacy and Safety of Saxagliptin When Added to Metformin Therapy in Patients With Inadequately Controlled Type 2 Diabetes With Metformin Alone

Ralph A. DeFronzo, MD, Miguel N. Hissa, MD, Alan J. Garber, MD, PHD, Jorge Luiz Gross, MD, Raina Yuyan Duan, PHD, Shoba Ravichandran, MD, Roland S. Chen, MD, for the Saxagliptin 014 Study Group

Diabetes Care 2009;32(9):1649–1655

DOI: https://doi.org/10.2337/dc08-1984

Published: 28 May 2009

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Includes: Supplementary data

Journal Articles

Fasting Versus Postload Plasma Glucose Concentration and the Risk for Future Type 2 Diabetes: Results from the Botnia Study

Muhammad A. Abdul-Ghani, MD, PHD, Valeriya Lyssenko, MD, PHD, Tiinamaija Tuomi, MD, PHD, Ralph A. DeFronzo, MD, Leif Groop, MD

Diabetes Care 2009;32(2):281–286

DOI: https://doi.org/10.2337/dc08-1264

Published: 01 February 2009

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Journal Articles

Efficacy and Safety of the Dipeptidyl Peptidase-4 Inhibitor Alogliptin in Patients With Type 2 Diabetes and Inadequate Glycemic Control: A randomized, double-blind, placebo-controlled study

Ralph A. DeFronzo, MD, Penny R. Fleck, MT, Craig A. Wilson, PHD, Qais Mekki, MD, PHD, on behalf of the Alogliptin Study 010 Group

Diabetes Care 2008;31(12):2315–2317

DOI: https://doi.org/10.2337/dc08-1035

Published: 01 December 2008

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Includes: Supplementary data

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NARROW

Prediction of Diabetes Based on Baseline Metabolic Characteristics in Individuals at High Risk

Characterization of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and Subjects With Type 2 Diabetes

Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study

In Vivo Actions of Peroxisome Proliferator–Activated Receptors: Glycemic control, insulin sensitivity, and insulin secretion

Pathophysiologic Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes

Is Incretin-Based Therapy Ready for the Care of Hospitalized Patients With Type 2 Diabetes?: The time has come for GLP-1 receptor agonists!

Two-Step Approach for the Prediction of Future Type 2 Diabetes Risk

Type 2 Diabetes Can Be Prevented With Early Pharmacological Intervention

The Relationship Between β-Cell Function and Glycated Hemoglobin: Results from the Veterans Administration Genetic Epidemiology Study

Bromocriptine: A Sympatholytic, D2-Dopamine Agonist for the Treatment of Type 2 Diabetes

Reduced Time Points to Calculate the Composite Index

Effects of Exenatide Plus Rosiglitazone on β-Cell Function and Insulin Sensitivity in Subjects With Type 2 Diabetes on Metformin

Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose

Plasma Glucose Concentration and Prediction of Future Risk of Type 2 Diabetes

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels: Response to Utzschneider et al.

Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance

The Efficacy and Safety of Saxagliptin When Added to Metformin Therapy in Patients With Inadequately Controlled Type 2 Diabetes With Metformin Alone

Fasting Versus Postload Plasma Glucose Concentration and the Risk for Future Type 2 Diabetes: Results from the Botnia Study

Efficacy and Safety of the Dipeptidyl Peptidase-4 Inhibitor Alogliptin in Patients With Type 2 Diabetes and Inadequate Glycemic Control: A randomized, double-blind, placebo-controlled study

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