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Journal Articles

Effect of 48 Months of Closed-Loop Insulin Delivery on Residual C-Peptide Secretion and Glycemic Control in Newly Diagnosed Youth With Type 1 Diabetes: A Randomized Trial

Julia Ware, Charlotte K. Boughton, Janet M. Allen, Malgorzata E. Wilinska, Sara Hartnell, Ajay Thankamony, Tabitha Randell, Atrayee Ghatak, Rachel E.J. Besser, Daniela Elleri, Nicola Trevelyan, Fiona M. Campbell, Judy Sibayan, Ryan Bailey, Peter Calhoun, Gareth Dunseath, Roman Hovorka, CLOuD Consortium, Tabitha Randell, Vreni Verhoeven, Roman Hovorka, Ajay Thankmonay, Carlo Acerini, David Dunger, Charlotte Boughton, Julia Ware, Martin Tauschmann, Rama Lakshman, Janet Allen, Malgorzata Wilinska, Sara Hartnell, Alina Cezar, Nicole Ashcroft, Mirela de Barros Tamarozzi, Meena Murthy, Atrayee Ghatak, Keith Thornborough, Jonathon Mimnagh, Joanne Shakeshaft, Karen Phelan, Rachel Besser, Rebecca Law, Clare Megson, Jane Haest, Alison West, Imogen Stamford, Daniela Elleri, Morag McDonald, Nicola Trevelyan, Helen Dewar, Rachel Brampton, Gabrielle Price, Gillian Crouch, Fiona Campbell, James Yong, Emily Metcalfe, Andrew Cameron, Julia Lawton, David Rankin, Judy Sibayan, Peter Calhoun, Ryan Bailey, Jessica Rusnak, Brian Bugielski, Gareth Dunseath, Stephen Luzio, Elisabeth Northam, John Todd, Stéphane Roze, Eleanor Scott, Tim Jones, Chris Patterson, Peter Adolfsson, John Gregory, Stephen Greene, Jo Blair, Alexia Passmore
Journal: Diabetes Care
Diabetes Care 2024;47(8):1441–1448
https://doi.org/10.2337/dc24-0360
Published: 26 June 2024
View article titled, Effect of 48 Months of Closed-Loop Insulin Delivery on Residual C-Peptide Secretion and Glycemic Control in Newly Diagnosed Youth With Type 1 Diabetes: A Randomized Trial
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Journal Articles

Fully Closed-Loop Glucose Control Compared With Insulin Pump Therapy With Continuous Glucose Monitoring in Adults With Type 1 Diabetes and Suboptimal Glycemic Control: A Single-Center, Randomized, Crossover Study

Charlotte K. Boughton, Sara Hartnell, Rama Lakshman, Munachiso Nwokolo, Malgorzata E. Wilinska, Julia Ware, Janet M. Allen, Mark L. Evans, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2023;46(11):1916–1922
https://doi.org/10.2337/dc23-0728
Published: 24 August 2023
View article titled, Fully Closed-Loop Glucose Control Compared With Insulin Pump Therapy With Continuous Glucose Monitoring in Adults With Type 1 Diabetes and Suboptimal Glycemic Control: A Single-Center, Randomized, Crossover Study
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Journal Articles

Cambridge Hybrid Closed-Loop System in Very Young Children With Type 1 Diabetes Reduces Caregivers’ Fear of Hypoglycemia and Improves Their Well-being

Carine de Beaufort, Ulrike Schierloh, Ajay Thankamony, Julia Ware, Malgorzata E. Wilinska, Elke Fröhlich-Reiterer, Thomas M. Kapellen, Birgit Rami-Merhar, Sabine E. Hofer, Fiona M. Campbell, James Yong, Laura E. Bocchino, Judy Sibayan, Julia Lawton, Stephane Roze, Maria Fritsch, Alena Thiele, Janet M. Allen, Charlotte Boughton, Julia K. Mader, Craig Kollman, Roman Hovorka, Ineke M. Pit-ten Cate, on behalf of the KidsAP Consortium
Journal: Diabetes Care
Diabetes Care 2022;45(12):3050–3053
https://doi.org/10.2337/dc22-0693
Published: 04 October 2022
View article titled, Cambridge Hybrid Closed-Loop System in Very Young Children With Type 1 Diabetes Reduces Caregivers’ Fear of Hypoglycemia and Improves Their Well-being
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Journal Articles

Perioperative Fully Closed-Loop Insulin Delivery in Patients Undergoing Elective Surgery: An Open-Label, Randomized Controlled Trial

David Herzig, Simon Suhner, Jonathan Roos, Daniel Schürch, Luca Cecchini, Christos T. Nakas, Salome Weiss, Alexander Kadner, Gregor J. Kocher, Dominik P. Guensch, Malgorzata E. Wilinska, Andreas Raabe, Klaus A. Siebenrock, Guido Beldi, Beat Gloor, Roman Hovorka, Andreas P. Vogt, Lia Bally
Journal: Diabetes Care
Diabetes Care 2022;45(9):2076–2083
https://doi.org/10.2337/dc22-0438
Published: 26 July 2022
View article titled, Perioperative Fully Closed-Loop Insulin Delivery in Patients Undergoing Elective Surgery: An Open-Label, Randomized Controlled Trial
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Journal Articles

User Engagement With the CamAPS FX Hybrid Closed-Loop App According to Age and User Characteristics

Natalie S. Chen, Charlotte K. Boughton, Sara Hartnell, Julia Fuchs, Janet M. Allen, Malgorzata E. Willinska, Ajay Thankamony, Carine de Beaufort, Fiona M. Campbell, Elke Fröhlich-Reiterer, Sabine E. Hofer, Thomas M. Kapellen, Birgit Rami-Merhar, Atrayee Ghatak, Tabitha L. Randell, Rachel E. J. Besser, Daniela Elleri, Nicola Trevelyan, Louise Denvir, Nikki Davis, Eleanor Gurnell, Robert Lindsay, Damian Morris, Eleanor M. Scott, Lia Bally, Hood Thabit, Lalantha Leelarathna, Mark L. Evans, Helen R. Murphy, Julia K. Mader, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2021;44(7):e148–e150
https://doi.org/10.2337/dc20-2762
Published: 20 July 2021
View article titled, User Engagement With the CamAPS FX Hybrid Closed-Loop App According to Age and User Characteristics
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Journal Articles

Duration of Hybrid Closed-Loop Insulin Therapy to Achieve Representative Glycemic Outcomes in Adults With Type 1 Diabetes

Lalantha Leelarathna, Hood Thabit, Malgorzata E. Willinska, Lia Bally, Julia K. Mader, Sabine Arnolds, Carsten Benesch, Thomas R. Pieber, Viral N. Shah, Anders L. Carlson, Richard M. Bergenstal, Mark L. Evans, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2020;43(3):e38–e39
https://doi.org/10.2337/dc19-2041
Published: 16 January 2020
View article titled, Duration of Hybrid Closed-Loop Insulin Therapy to Achieve Representative Glycemic Outcomes in Adults With Type 1 Diabetes
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Journal Articles

Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range

Tadej Battelino, Thomas Danne, Richard M. Bergenstal, Stephanie A. Amiel, Roy Beck, Torben Biester, Emanuele Bosi, Bruce A. Buckingham, William T. Cefalu, Kelly L. Close, Claudio Cobelli, Eyal Dassau, J. Hans DeVries, Kim C. Donaghue, Klemen Dovc, Francis J. Doyle, III, Satish Garg, George Grunberger, Simon Heller, Lutz Heinemann, Irl B. Hirsch, Roman Hovorka, Weiping Jia, Olga Kordonouri, Boris Kovatchev, Aaron Kowalski, Lori Laffel, Brian Levine, Alexander Mayorov, Chantal Mathieu, Helen R. Murphy, Revital Nimri, Kirsten Nørgaard, Christopher G. Parkin, Eric Renard, David Rodbard, Banshi Saboo, Desmond Schatz, Keaton Stoner, Tatsuiko Urakami, Stuart A. Weinzimer, Moshe Phillip
Journal: Diabetes Care
Diabetes Care 2019;42(8):1593–1603
https://doi.org/10.2337/dci19-0028
Published: 08 June 2019
View article titled, Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range
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Includes: Supplementary data
Journal Articles

Young Children Have Higher Variability of Insulin Requirements: Observations During Hybrid Closed-Loop Insulin Delivery

Klemen Dovc, Charlotte Boughton, Martin Tauschmann, Hood Thabit, Lia Bally, Janet M. Allen, Carlo L. Acerini, Sabine Arnolds, Carine de Beaufort, Richard M. Bergenstal, Fiona Campbell, Amy Criego, David B. Dunger, Daniella Elleri, Mark L. Evans, Elke Fröhlich-Reiterer, Sabine Hofer, Thomas Kapellen, Lalantha Leelarathna, Thomas R. Pieber, Birgit Rami-Merhar, Viral N. Shah, Judy Sibayan, Malgorzata E. Wilinska, Roman Hovorka, APCam11, AP@Home, and KidsAP Consortia, Klemen Dovc, Martin Tauschmann, Charlotte Boughton, Gianluca Musolino, Hood Thabit, Lia Bally, Sonja Slegtenhorst, Janet M. Allen, Malgorzata E. Wilinska, Yue Ruan, Josephine Hayes, Nicole Barber, Jane Curtis, Carlo L. Acerini, David B. Dunger, Mark L. Evans, Roman Hovorka, Lalantha Leelarathna, Hood Thabit, Angel Shaju, Stefanie Yau, Linda James, Karthirani Balakrishnan, Denise Donahue, Womba Mubita, Jane Exall, James Yong, Rachel Forshaw, Rebecca Pad, Stephanie Heath, Emily Metcalfe, Fiona Campbell, Judy Sibayan, Craig Kollman, Peiyao Cheng, Roy W. Beck, John Lum, Sarah Borgman, Viki Huegel, Sydnee Bradshaw, Amanda Hellman, Nanadan Patibandla, Chris McCarthy, Carlos Murphy, Brian Bugielski, Barvan Alvarado, Daniella Elleri, Morag McDonald, Louise Bath, Harriet Miles, Debbie Miller, Emily Collett, Julie Baggott, Key Riding, Jane Thomson, Richard M. Bergenstal, Amy Criego, Anders B. Carlson, Thomas Martens, Shannon Beasley, M. Madden, Beth Olson, Jamie Hyatt, Charlotte Ashanti, Vera Mikityuk, LeeAnn Thomas, Wanda Konerza, Viral N. Shah, Hal Joseph, Christie R. Beatson, Jamie K. Demmitt, Prakriti Joshee, Dawn White, Harald Kojzar, Julia K. Mader, Elisabeth Suppan, Thomas R. Pieber, Erike E. Fröhlich-Reiterer, Martin Ellmerer, Manuel Holzer, Dominique Schaeffer, Muriel Fichelle, Ulrike Schierloh, Carine de Beaufort, Alena G. Thiele, Heike Bartelt, Thomas M. Kapellen, Daniela Abt, Dagmar Meraner, Elisabeth Binder, Elisabeth Steichen, Lukas Hackl, Sabine Hofer, Birgit Rami Merhar, Maria Fritsch, Katrin Nagl, Sonja Katzenbeisser-Pawlik, Martin Tauschmann, Sabine Arnolds, Carsten Benesch, Sibylle Dellweg, Martina Haase, Lutz Heinemann, Kirstin Kuschma, Maren Luebkert, Elke Przetak, Krisztina Schmitz-Grozs
Journal: Diabetes Care
Diabetes Care 2019;42(7):1344–1347
https://doi.org/10.2337/dc18-2625
Published: 21 May 2019
View article titled, Young Children Have Higher Variability of Insulin Requirements: Observations During Hybrid Closed-Loop Insulin Delivery
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Includes: Supplementary data
Journal Articles

Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data

Lalantha Leelarathna, Roy W. Beck, Richard M. Bergenstal, Hood Thabit, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2019;42(4):e60–e61
https://doi.org/10.2337/dc18-2479
Published: 06 February 2019
View article titled, Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data
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Journal Articles

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial

Martin Tauschmann, Janet M. Allen, Katrin Nagl, Maria Fritsch, James Yong, Emily Metcalfe, Dominique Schaeffer, Muriel Fichelle, Ulrike Schierloh, Alena G. Thiele, Daniela Abt, Harald Kojzar, Julia K. Mader, Sonja Slegtenhorst, Nicole Barber, Malgorzata E. Wilinska, Charlotte Boughton, Gianluca Musolino, Judy Sibayan, Nathan Cohen, Craig Kollman, Sabine E. Hofer, Elke Fröhlich-Reiterer, Thomas M. Kapellen, Carlo L. Acerini, Carine de Beaufort, Fiona Campbell, Birgit Rami-Merhar, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2019;42(4):594–600
https://doi.org/10.2337/dc18-1881
Published: 28 January 2019
View article titled, Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial
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Includes: Supplementary data
Journal Articles

Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial

Zoe A. Stewart, Malgorzata E. Wilinska, Sara Hartnell, Leanne K. O’Neil, Gerry Rayman, Eleanor M. Scott, Katharine Barnard, Conor Farrington, Roman Hovorka, Helen R. Murphy
Journal: Diabetes Care
Diabetes Care 2018;41(7):1391–1399
https://doi.org/10.2337/dc17-2534
Published: 13 March 2018
View article titled, Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial
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Includes: Supplementary data
Journal Articles

International Consensus on Use of Continuous Glucose Monitoring

Thomas Danne, Revital Nimri, Tadej Battelino, Richard M. Bergenstal, Kelly L. Close, J. Hans DeVries, Satish Garg, Lutz Heinemann, Irl Hirsch, Stephanie A. Amiel, Roy Beck, Emanuele Bosi, Bruce Buckingham, Claudio Cobelli, Eyal Dassau, Francis J. Doyle, III, Simon Heller, Roman Hovorka, Weiping Jia, Tim Jones, Olga Kordonouri, Boris Kovatchev, Aaron Kowalski, Lori Laffel, David Maahs, Helen R. Murphy, Kirsten Nørgaard, Christopher G. Parkin, Eric Renard, Banshi Saboo, Mauro Scharf, William V. Tamborlane, Stuart A. Weinzimer, Moshe Phillip
Journal: Diabetes Care
Diabetes Care 2017;40(12):1631–1640
https://doi.org/10.2337/dc17-1600
Published: 10 November 2017
View article titled, International Consensus on Use of Continuous Glucose Monitoring
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Includes: Supplementary data
Journal Articles

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Suboptimally Controlled Adolescents With Type 1 Diabetes: A 3-Week, Free-Living, Randomized Crossover Trial

Martin Tauschmann, Janet M. Allen, Malgorzata E. Wilinska, Hood Thabit, Carlo L. Acerini, David B. Dunger, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2016;39(11):2019–2025
https://doi.org/10.2337/dc16-1094
Published: 09 September 2016
View article titled, Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Suboptimally Controlled Adolescents With Type 1 Diabetes: A 3-Week, Free-Living, Randomized Crossover Trial
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Includes: Supplementary data
Journal Articles

Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report

David M. Maahs, Bruce A. Buckingham, Jessica R. Castle, Ali Cinar, Edward R. Damiano, Eyal Dassau, J. Hans DeVries, Francis J. Doyle, III, Steven C. Griffen, Ahmad Haidar, Lutz Heinemann, Roman Hovorka, Timothy W. Jones, Craig Kollman, Boris Kovatchev, Brian L. Levy, Revital Nimri, David N. O’Neal, Moshe Philip, Eric Renard, Steven J. Russell, Stuart A. Weinzimer, Howard Zisser, John W. Lum
Journal: Diabetes Care
Diabetes Care 2016;39(7):1175–1179
https://doi.org/10.2337/dc15-2716
Published: 20 March 2016
View article titled, Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report
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Journal Articles

Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes

Yue Ruan, Hood Thabit, Lalantha Leelarathna, Sara Hartnell, Malgorzata E. Willinska, Sibylle Dellweg, Carsten Benesch, Julia K. Mader, Manuel Holzer, Harald Kojzar, Mark L. Evans, Thomas R. Pieber, Sabine Arnolds, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2016;39(5):830–832
https://doi.org/10.2337/dc15-2623
Published: 10 March 2016
View article titled, Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial

Martin Tauschmann, Janet M. Allen, Malgorzata E. Wilinska, Hood Thabit, Zoë Stewart, Peiyao Cheng, Craig Kollman, Carlo L. Acerini, David B. Dunger, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2016;39(7):1168–1174
https://doi.org/10.2337/dc15-2078
Published: 13 November 2015
View article titled, Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial
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Includes: Supplementary data
Journal Articles

Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197

Nick S. Oliver, Mark L. Evans, Roman Hovorka, Simon Heller, Desmond G. Johnston, Stephanie A. Amiel, Katharine Barnard
Journal: Diabetes Care
Diabetes Care 2014;37(10):e226–e227
https://doi.org/10.2337/dc14-1499
Published: 10 September 2014
View article titled, Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197
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Journal Articles

Day and Night Home Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes: Three-Center Randomized Crossover Study

Lalantha Leelarathna, Sibylle Dellweg, Julia K. Mader, Janet M. Allen, Carsten Benesch, Werner Doll, Martin Ellmerer, Sara Hartnell, Lutz Heinemann, Harald Kojzar, Lucy Michalewski, Marianna Nodale, Hood Thabit, Malgorzata E. Wilinska, Thomas R. Pieber, Sabine Arnolds, Mark L. Evans, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2014;37(7):1931–1937
https://doi.org/10.2337/dc13-2911
Published: 12 June 2014
View article titled, Day and Night Home Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes: Three-Center Randomized Crossover Study
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Includes: Supplementary data
Journal Articles

Pharmacokinetics of Insulin Aspart in Pregnant Women With Type 1 Diabetes: Every Day Is Different

Robert J.B. Goudie, David Lunn, Roman Hovorka, Helen R. Murphy
Journal: Diabetes Care
Diabetes Care 2014;37(6):e121–e122
https://doi.org/10.2337/dc13-2535
Published: 10 May 2014
View article titled, Pharmacokinetics of Insulin Aspart in Pregnant Women With Type 1 Diabetes: Every Day Is Different
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Journal Articles

Feasibility of Closed-Loop Insulin Delivery in Type 2 Diabetes: A Randomized Controlled Study

Kavita Kumareswaran, Hood Thabit, Lalantha Leelarathna, Karen Caldwell, Daniela Elleri, Janet M. Allen, Marianna Nodale, Malgorzata E. Wilinska, Mark L. Evans, Roman Hovorka
Journal: Diabetes Care
Diabetes Care 2014;37(5):1198–1203
https://doi.org/10.2337/dc13-1030
Published: 10 April 2014
View article titled, Feasibility of Closed-Loop Insulin Delivery in Type 2 Diabetes: A Randomized Controlled Study
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Includes: Supplementary data