A 71-year-old Caucasian man with a history of type 2 diabetes, stage 3 chronic kidney disease, hypertension, coronary artery disease, and depression presented to his primary care provider (PCP) for routine diabetes follow-up. At the time of his visit, his antidiabetic medication regimen included metformin extended release 500 mg twice daily and glyburide 10 mg daily. His other chronic and stable medications included aspirin 81 mg daily, cholecalciferol 1,000 units daily, fenofibrate 145 mg daily, lisinopril 2.5 mg daily, rosuvastatin 5 mg daily, and trazodone 100 mg as needed. The patient reported that he had started a walking routine and reduced his overall dietary carbohydrate intake since his last visit, resulting in a 10-lb weight loss.

Despite these lifestyle changes, his A1C remained elevated at 8.7%; it had been 8.8% previously. It was determined that additional drug therapy was needed for glycemic management. The patient was receptive to a medication...

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