The incidence of type 2 diabetes in children is rising and carries a worse prognosis than in adults. The influence of sex on pediatric type 2 diabetes outcomes has not been well investigated. We studied 715 youth with type 2 diabetes diagnosed at a median age of 13.7 years and compared sex differences in demographic, clinical, and laboratory characteristics within the first year of diagnosis. Females diagnosed with type 2 diabetes were younger and at a higher stage of pubertal development than males, yet presented with lower A1Cs, a lower prevalence of diabetic ketoacidosis, and higher HDL cholesterol levels.
Characteristics of Type 2 Diabetes in Female and Male Youth
Beatriz Castillo Rodriguez, Marcela Astudillo, Mustafa Tosur, Ahmad Rafaey, Siripoom McKay, Fida Bacha, Ashok Balasubramanyam, Maria J. Redondo; Characteristics of Type 2 Diabetes in Female and Male Youth. Clin Diabetes 1 April 2023; 41 (2): 239–243. https://doi.org/10.2337/cd22-0057
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