Obstructive sleep apnea (OSA) is a sleep disorder consisting of repetitive upper airway collapse that triggers hypoxemic episodes. OSA has been linked to increased risk of developing type 2 diabetes, as well as impaired glucose tolerance and elevated fasting glucose (1). Some studies have shown an association between OSA and nocturnal hyperglycemia in patients with type 2 diabetes (2).

Data on the effect of continuous positive airway pressure (CPAP) on glucose metabolism in patients with type 2 diabetes and OSA remain controversial, although some observational studies have revealed a significant reduction in mean nocturnal glucose levels with CPAP administration in patients with type 2 diabetes and severe OSA (3).

Herein, we present the case of a patient with type 2 diabetes presenting with refractory fasting hyperglycemia in the setting of OSA who was identified through continuous glucose monitoring (CGM) to have nocturnal hyperglycemia, which...

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