There are many numbers to keep in mind when we help people with diabetes manage their condition. Some are diagnosis criteria, others are therapeutic targets, and still others are related to specific treatments. Although these numbers may seem random or arbitrary to some of our patients, they are evidence based and derived from data related to diabetes pathophysiology and the prevention of complications. This article is part of a series explaining some of the key numbers related to diabetes management and summarizing the evidence underpinning them.

Because A1C is foundational to nearly all facets of diabetes care, the first installment of “Diabetes by the Numbers” focused on A1C (1). However, there are too many A1C- related numbers discussed in the American Diabetes Association (ADA) Standards of Care in Diabetes—2024 to be adequately covered in a single article. Thus, this is a continuation of our exploration of key A1C...

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