A holistic approach to obesity management is essential, encompassing nutrition counseling, regular exercise, behavioral strategies, and diabetes self-management education to ensure effective and sustainable results.

In people with type 2 diabetes and overweight or obesity, weight management should represent a primary goal of treatment along with glycemic management.

  • Delays progression from prediabetes to type 2 diabetes

  • Is highly beneficial in treating type 2 diabetes

  • Improves glycemia and reduces the need for glucose-lowering medications

  • Reduces cardiovascular risk factors, lowering long-term cardiovascular and mortality risks

  • Reduces other obesity-related health risks

  • Use person-centered, nonjudgmental, person-first language (e.g., “person with diabetes” rather than “diabetic person” and “person with obesity” rather than “obese person”).

  • Calculate BMI and perform measures body fat distribution (e.g., waist circumference, waist-to-hip ratio, and/or waist-to-height ratio).

  • Monitor obesity-related parameters at least annually to guide treatment decisions.

ER, extended release

  • Consider weight when choosing glucose-lowering medications for individuals with type 2 diabetes and overweight or obesity.

  • When possible, avoid prescribing medications that cause weight gain to treat comorbid conditions.

  • Obesity pharmacotherapy should be considered for people with diabetes and overweight or obesity along with lifestyle changes. Potential benefits and risks must be considered.

  • Continue obesity pharmacotherapy if it is effective (>5% weight loss after 3 months).

  • Consider changing or stopping treatment if weight loss is <5% after 3 months or if significant safety/tolerability issues arise.

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