• Periodically check serum creatinine and potassium levels when ACE inhibitor, angiotensin receptor blocker (ARB), or nonsteroidal mineralcorticoid receptor antagonist is used.

  • Do not discontinue ACE inhibitor or ARB therapy for increases ≤30% increases in serum creatinine in the absence of volume depletion.

  • Aim for a urinary albumin reduction ≥30% in people with CKD and urinary albumin ≥300 mg/g to slow CKD progression.

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