Carefully managing people with diabetes during hospitalization can reduce the risk of hyperglycemia, hypoglycemia, or glucose variability, which all lead to adverse outcomes, including death. Consult with a specialized diabetes or glucose management team when possible.

  • Institute validated order sets for management of dysglycemia in the hospital.

  • State the type of diabetes on the initial evaluation when it is known.

  • Perform an A1C test on all hospitalized people with diabetes or hyperglycemia (random blood glucose >140 mg/dL [7.8 mmol/L]) if no A1C result is available from the prior 3 months.

  • Assess diabetes self-management knowledge and behaviors on admission and provide self-management education when needed.

  • If feasible, continue use of personal continuous glucose monitoring and/or insulin pump therapy when clinically appropriate, with confirmatory point-of-care blood glucose monitoring for insulin dosing decisions and hypoglycemia assessment and treatment.

  • Initiate or intensify insulin and/or other glucose-lowering therapies for persistent hyperglycemia at a threshold of ≥180 mg/dL.

A1C and glucose goals 
  • Elective surgery A1C goal: <8% (<64.0 mmol/L)

  • Blood glucose goal within 4 hours of surgery: 100–180 mg/dL (5.6–10.0 mmol/L)

  • CGM alone should not be used for glucose monitoring during surgery.

 
Medication adjustments 
  • Hold metformin on the day of surgery.

  • Discontinue sodium–glucose cotransporter 2 inhibitors 3–4 days before surgery.

  • Hold other oral glucose-lowering agents the morning of the surgery or procedure.

  • Consider holding glucagon-like peptide 1 receptor agonists on the day of the procedure or surgery for daily-dose agents and for at least 7 days before the procedure or surgery for once-weekly agents.

  • Individualize plan based on type of procedure or surgery.

 
Insulin therapy adjustments 
  • Give half of NPH dose or 75–80% of long-acting analog insulin dose or adjust insulin pump basal rates based on diabetes type and clinical judgment.

 
A1C and glucose goals 
  • Elective surgery A1C goal: <8% (<64.0 mmol/L)

  • Blood glucose goal within 4 hours of surgery: 100–180 mg/dL (5.6–10.0 mmol/L)

  • CGM alone should not be used for glucose monitoring during surgery.

 
Medication adjustments 
  • Hold metformin on the day of surgery.

  • Discontinue sodium–glucose cotransporter 2 inhibitors 3–4 days before surgery.

  • Hold other oral glucose-lowering agents the morning of the surgery or procedure.

  • Consider holding glucagon-like peptide 1 receptor agonists on the day of the procedure or surgery for daily-dose agents and for at least 7 days before the procedure or surgery for once-weekly agents.

  • Individualize plan based on type of procedure or surgery.

 
Insulin therapy adjustments 
  • Give half of NPH dose or 75–80% of long-acting analog insulin dose or adjust insulin pump basal rates based on diabetes type and clinical judgment.

 

Tailor a structured discharge plan to the individual with diabetes:

  • Transmit discharge summaries to the primary care clinician as soon as possible after discharge.

  • Provide diabetes self-management education before discharge.

  • Ensure medication reconciliation and access.

  • Arrange virtual or in-person follow-up visits post-discharge:

    • » Schedule a visit with the primary care clinician, endocrinologist, or a diabetes care and education specialist within 1 month of discharge.

    • » Schedule earlier follow-up (1–2 weeks) if medications change or glucose goals are not met at discharge.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/journals/pages/license.