A young diabetic patient with ketoacidosis responding to standard treatment abruptly developed pulmonary edema, apnea, coma, cardiac arrythmias and diabetes insipidus. At autopsy, cerebral edema and neuronal degeneration were present. In the hypothalamus many neurones were absent. Similar cases have been reported, but the pathogenesis of the syndrome is not understood. The present patient received large amounts of sodium bicarbonate, and significant potassium deficiency may have been present.
Brief Notes and Comments| February 01 1968
Cerebral Edema, Diabetes Insipidus, and Sudden Death during the Treatment of Diabetic Ketoacidosis
Howard Taubin, M.D.;
Howard Taubin, Robert Matz; Cerebral Edema, Diabetes Insipidus, and Sudden Death during the Treatment of Diabetic Ketoacidosis. Diabetes 1 February 1968; 17 (2): 108–109. https://doi.org/10.2337/diab.17.2.108
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