When acute (four-hour) hyponatremia with clinical signs of water intoxication was produced in normal weanling mice by the use of hypotonie glucose or deionized water, there was a two-to-fourfold increase in plasma glucose concentration. Concomitantly, concentrations of plasma insulin fell 63 to 68 per cent, whereas plasma glue agon increased to 262 per cent of control. The findings are compatible with stress-induced catecholamine release.
Original Contributions| January 01 1978
Hyperglycemia, Hypoinsulinemia, and Hyperglucagonemia in Acute Water Intoxication
Jean Holowach Thurston, MD;
Richard E Hauhart;
Jean Holowach Thurston, Richard E Hauhart, John A Dirgo; Hyperglycemia, Hypoinsulinemia, and Hyperglucagonemia in Acute Water Intoxication. Diabetes 1 January 1978; 27 (1): 61–63. https://doi.org/10.2337/diab.27.1.61
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