Dr. Elliott P. Joslin laid the foundation for his lifetime interest in diabetes at the beginning of his medical career. The results of his careful study of the early medical records of the Massachusetts General Hospital published in collaboration with Dr. Fitz 57 years ago reveal information of interest from the viewpoint of the medical historian. The paper is also instructive from two other points of view. The importance of careful observation and sound evaluation of clinical data is illustrated. The progress which has been made in the therapy of diabetes since its initial publication represents a challenge to the future.

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