Background: Although the resistant starch (RS) supplementation has shown promise in lowering postprandial glucose in healthy non-obese persons, little is known about the effect of RS on postprandial glucose levels in abdominally obese persons.

Objective: This study examined the effect of RS-supplemented muffins on postprandial glucose levels in sedentary, abdominally obese individuals as compared with digestible carbohydrates-matched oral glucose solution.

Method: A total of 8 sedentary, abdominally obese participants were randomly assigned to two sequences of treatments (AB, BA) using a 2 x 2 randomized cross-over design. The treatment effect tested with a muffin that contained 75 g of digestible carbohydrates and 30 g of RS (TRT), while the control tested using a 75-g oral glucose solution as a control condition (CON). Linear mixed models were used to test the treatment effect (TRT vs. CON) on glucose values and area under the curve (AUC).

Results: The 2-h postprandial glucose AUC was significantly lower in the TRT than in the CON (12.5±1.6 mmol/L·h vs. 15.6±3 mmol/L·h, P=0.002). The glucose levels were also significantly lower in the TRT than in the CON at 30 minutes (6.6±0.8 vs. 8.3±1.3 mmol/L, P=0.001), 60 minutes (6.6 ± 1.1 vs. 8.5 ± 2.1 mmol/L, P=0.004), and 90 minutes (6.3±1.1 vs. 8.1±1.8 mmol/L, P=0.003). The 2-h postprandial insulin AUC was also significantly lower in the TRT than in the CON (1354.5±6vs. 1788.9±522.8 pmol/L·h, P<0.001). Based on the 2-h glucose incremental AUC values, the calculated glycemic index of the RS-supplemented muffins was 48 (glucose=100).

Conclusion: The RS muffins supplemented with 30 g of RS could reduce postprandial glucose and insulin responses in abdominally obese adults.


T. Ma: None. C. Lee: None.

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