In this investigation, we compared the performance of various parameters including Waist-to-Height Ratio (WHtR), Waist-Hip Ratio (WHR), Waist Circumference (WC), Body Mass Index (BMI), and triglycerides glucose related Index including TyG index, TyG-BMI, TyG-WC in detecting Metabolic Syndrome (MS). (TyG index: TG× FPG, TyG-BMI: TyG index × BMI, TyG-WC: TyG index × WC) In 2013, 2972 registered permanent residents in a rural satellite town of Beijing, aged ≥ 20 years, were invited to participate in the study. MS patients were identified with the criteria of Chinese Diabetes Society (CDS). The receiver-operating characteristics (ROC) curve analyses and the respective area under the ROC curves (AUC) were used to compare the association of the different index with MS.In men, the AUC was 0.81 (0.78-0.84) for BMI, 0.77 (0.74-0.81) for WHtR, 0.68 (0.63-0.72) for WHR, 0.77 (0.74-0.80) for WC in detecting MS, respectively. In women, the AUC was 0.78 (0.76-0.81), 0.76 (0.73-0.78), 0.66 (0.64-0.68), 0.76(0.74-0.78), respectively. The correlation between BMI and MS was higher than other indicators by comparing AUCs (P<0.05). In men, the AUC was 0.88 (0.86-0.90) for TyG index, 0.89 (0.87-0.92) for TyG-BMI, 0.88 (0.86-0.90) for TyG-WC, respectively. In women, the AUC was 0.88 (0.86-0.90), 0.88 (0.86-0.92), 0.87 (0.85-0.89), respectively. There were no significant differences for these three indexes. However, the correlation between TyG index and MS was higher than BMI (P<0.05).The cut-off points for BMI evaluating MS were 25.0 Kg/m2 in men and 25.3 Kg/m2 in women, and for TyG index were 8.87 in men and 8.80 in women. BMI is an efficient surrogate marker in the evaluation of MS in Chinese people. It can be used to screen MS patients and self-assess the risk in common people easily. TyG index is better than BMI in the evaluation of MS. This will help general practitioners to assess the risks of their patients quickly.

Disclosure

Z. Xin: None.

Funding

Expert Promotion Program of Beijing Health Systems (2015-3-017)

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