Objective: The association between uncontrolled diabetes mellitus (DM) and liver disease (LD) has been established. The impact of different etiologies of LD on specific DM complications (Cx) is not well known. The aim of this study is to determine if the frequency of DM complications are related to specific LD etiologies.

Methods: This is a cross-sectional study of the 2016 National Inpatient Sample database. Adult patients with type 2 DM were studied. ICD-10 CM codes were used to identify DM complications and different LD etiologies. Univariate analyses and multivariate logistic regressions were performed.

Results: 1,538,604 patients met inclusion criteria. The prevalence of DM complications was 26.9%. Based on multivariate analysis results (Table 1), kidney Cx were associated with increased viral hepatitis. Ophthalmic Cx were preferentially associated with an increased prevalence of hepatitis B but not C. Skin and circulatory Cx were associated with less reported in all LD, while neurological Cx were associated more with reported LD.

Conclusion: Among inpatients, the prevalence of DM Cx differ by LD, with more significant differences noted for patients with Hepatitis etiologies. Our analysis is limited with retrospective nature and should be supported with future prospective studies.


M.A. Minhem: None. A. Nakshabandi: None. M. Cerasale: None.

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