Introduction: Stroke remains a leading cause of mortality and disability in the United States, presenting significant public health and economic challenges. Among the various risk factors contributing to the incidence of stroke, high fasting plasma glucose levels (FPG) have emerged as a critical element.
Method: Using Global Burden of Disease tool, deaths and disability adjusted life years (DALYs) due to stroke attributable to FPG were estimated by age, sex, year across the US from 1990-2019.
Results: From 1990-2019, the annual percentage change (APC) in deaths rose by 77% (95% UI: 52-107%), and DALYs increased by 78% (56-106%). However, the age-standardized APC saw a 3% decrease in death rates, while DALY rates increased by 3%. Nevada experienced the highest increase in death APC at 338%, followed by Alaska at 312%, whereas Pennsylvania had the lowest at 18%. The highest death toll was in the 85-89 age group, and the most DALYs were seen in the 70-74 age group in 2019. Females showed a higher APC in both deaths (83% vs 70%) and DALYs (81% vs 74%) compared to males during this period.
Conclusion: Stroke related to FPG represented 28.68% of all stroke-related deaths. This significant proportion underscores the need for public health policymakers to take decisive action to address and mitigate this growing burden.
K. Maddineni: None. A. Parisapogu: None. M. Chinthapalli: None. G. Potluri: None. K. Markandu: None. H. Islam: None. R. Islam: None. A. Dekhne: None. H. Desai: None.
