Insulin-like Activity

This presentat ion is a review of the ILA concept and considers (1) major insulin assays; description, comparison, and variation of results; (2) location of circulating ILA in the plasma proteins by various technics; (3) types of ILA: “free-bound,” “typical-atypical,” “suppressiblenonsuppressible,” “NSILA,” and other forms; (4) inhibitory or antagonistic factors: synalbumin-antagonistic albumin and nonesterified fatty acids; and (5) the ILA concept with respect to vascular membranes and the glucose transport theory. Also included are data comparing insulin levels obtained by the major assays, types of ILA-insulin levels and properties of the various forms of insulin.