Previous studies in normal females and in stilbestrolpretreated males have revealed increases in plasma insulin and growth hormone (HGH), after infusion of arginine monochloride, and a sharp decrease in free fatty acids (FFA), which return toward normal over two to two and one-half hours. In the present study, similar measurements were made after arginine infusion in subjects who were deficient only in HGH. The rise in plasma insulin levels in the HGH-deficient subjects was less than half the normal response. The fall in plasma FFA levels was similar in normal and in HGH-deficient subjects, but the HGHdeficient group failed to restore their FFA levels to control values over the time of the experiment.
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Original Contributions| July 01 1967
Influence of Growth Hormone on Insulin Secretion: Studies of Growth-Hormone Deficient Subjects
T J Merimee, MD;
J A Burgess, ALB, MRACP;
T J Merimee, J A Burgess, D Rabinowitz; Influence of Growth Hormone on Insulin Secretion: Studies of Growth-Hormone Deficient Subjects. Diabetes 1 July 1967; 16 (7): 478–482. https://doi.org/10.2337/diab.16.7.478
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