Infantile idiopathic hypoglycemia appears to be an early manifestation of an early manifestation of an inherited metabolic defect that leads to diabetes mellitus. Eight children with this form of hypoglycemia were studied for the presence of synalbumir insulin antagonism. All had diabetes in one or both parenta families. Two of the children had normal antagonist level. before and after they developed chemical diabetes. A thirt child was tested twice after she was found to have chemica diabetes, and on each occasion had normal antagonist levels. Rather than a causa sine qua non for the develop ment of diabetes, or a constant feature of the disorder, ex cess synalbumin insulin antagonism appears to be a variable expression of a more fundamental metabolic abnormality ir essential diabetes mellitus.
Skip Nav Destination
Article navigation
Original Contributions|
September 01 1968
Synalbumin Insulin Antagonism in Idiopathic Hypoglycemia of Infancy
Lawrence Sherman, M.D.;
Lawrence Sherman, M.D.
Department of Medicine, Long Island Jewish Hospital—Queens Hospital Center Affiliation
Jamaica, N. Y.
Department of Pediatrics, University of Wisconsin Medical Center
Madison, Wise
Search for other works by this author on:
Arlan L Rosenbloom, M.D.
Arlan L Rosenbloom, M.D.
Department of Medicine, Long Island Jewish Hospital—Queens Hospital Center Affiliation
Jamaica, N. Y.
Department of Pediatrics, University of Wisconsin Medical Center
Madison, Wise
Search for other works by this author on:
Address reprint requests to Dr. Lawrence Sherman, Dept. of Medicine, Queens Hospital Center, 82–68 164th Street, Jamaica, N.Y. 11432.
Diabetes 1968;17(9):557–559
Citation
Lawrence Sherman, Arlan L Rosenbloom; Synalbumin Insulin Antagonism in Idiopathic Hypoglycemia of Infancy. Diabetes 1 September 1968; 17 (9): 557–559. https://doi.org/10.2337/diab.17.9.557
Download citation file: