Two examples of “insulitis” (infiltration of pancreatic islets by mononuclear cells, apparently chiefly lymphocytes) are reported in adults with late-onset diabetes. Attempts to demonstrate cell-bound antibodies by immunofluorescent methods and to isolate a virus in one case were inconclusive. Possible implications with regard to auto-immune processes and virus infection in the etiology of diabetes are discussed.
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Original Contributions| June 01 1972
Insulitis (Lymphocytic Infiltration of Pancreatic Islets) in Late-onset Diabetes
Philip M LeCompte, M.D.;
Address reprint requests to Dr. Philip M. LeCompte, Faulkner Hospital, 1153 Centre Street, Boston, Massachusetts 02130.
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Philip M LeCompte, Merle A Legg; Insulitis (Lymphocytic Infiltration of Pancreatic Islets) in Late-onset Diabetes. Diabetes 1 June 1972; 21 (6): 762–769. https://doi.org/10.2337/diab.21.6.762
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