Subpopulations of peripheral lymphocytes were studied in 26 children with insulin-treated juvenile diabetes and in 27 control children of comparable age. T-lymphocytes were quantitated by spontaneous rosette-formation with sheep erythrocytes and B-lymphocytes by indirect immunofluorescence with the use of monovalent, fluorescein-labeled rabbit antiserum specific to the heavy chains of human IgG IgM, or IgA. No significant quantitative difference in subpopulations of the peripheral lymphocytes, T-cells, and B-cells with IgG, IgA, or IgM markers found between children with juvenile diabetes and the control group, although the B-lymphocytes with IgG or IgA markers tended to be higher and those with IgM markers lower in the diabetic than in the control group.
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Articles| February 01 1976
Subpopulations of Peripheral Lymphocytes in Juvenile Diabetes
Suhung Hann, M.D.;
Robert Kaye, M.D.;
Address reprint requests to Dr. S. Hann, Department of Pediatrics, Hahnemann Medical College, 230 N. Broad St., Philadelphia, Pa. 19102.
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Suhung Hann, Robert Kaye, Bonita Falkner; Subpopulations of Peripheral Lymphocytes in Juvenile Diabetes. Diabetes 1 February 1976; 25 (2): 101–103. https://doi.org/10.2337/diab.25.2.101
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