The microvascular complications of diabetes are demonstrated in the eye at a very early stage with the use of retinal ftuorescein angiography. One hundred and fifty-four children who have had diabetes mellitus for durations varying from one month to 18 years had their retinal vasculature evaluated with fluorescein angiography. Seventy-five per cent of the children examined had vascular abnormalities, including 20 children who had diabetes for one year or less. Twenty-five per cent of the children showed no vascular abnormalities. This included one child who had diabetes for 12 years. The severity of the vascular abnormalities increased with the duration of diabetes. Vascular abnormalities did not appear related to diabetic management or control. The possibility of two types of diabetes, one with and the other without associated vascular abnormalities, is suggested.
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Original Contributions|
July 01 1977
Diabetic Vascular Changes in Children
John I Malone, MD;
John I Malone, MD
Departments of Pediatrics and Ophthalmology, University of South Florida, College of Medicine
Tampa, Florida 33612
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Thomas C Van Cader;
Thomas C Van Cader
Departments of Pediatrics and Ophthalmology, University of South Florida, College of Medicine
Tampa, Florida 33612
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William C Edwards, MD
William C Edwards, MD
Departments of Pediatrics and Ophthalmology, University of South Florida, College of Medicine
Tampa, Florida 33612
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Citation
John I Malone, Thomas C Van Cader, William C Edwards; Diabetic Vascular Changes in Children. Diabetes 1 July 1977; 26 (7): 673–679. https://doi.org/10.2337/diab.26.7.673
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