Oxytocin Infusion Increases Plasma Insulin and Glucagon Levels and Glucose Production and Uptake in the Normal Dog

Infusion of oxytocin (50-500 μU/kg/min) into normal conscious dogs produces a rise in plasma glucose, insulin, and glucagon levels. These changes are accompanied by a prompt increase in glucose production followed by an increase in overall glucose uptake, as determined using 6-³H-glucose infusion.