Variant DNA sequences flanking the human insulin gene were found in the Danish population using restriction endonucleases (restriction fragment length polymorphism). The frequencies of these DNA sequences were determined in 47 non-insulin-dependent diabetics and 93 control individuals. We report an association between a restriction fragment length polymorphism of the insulin gene and NIDDM.
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Rapid Publications| March 01 1982
Restriction Fragment Length Polymorphism of the Insulin Gene in Diabetes Mellitus
Address reprint requests to Dr. Jprn Nerup, Steno Memorial Hospital, Niels Steensen Vej 2, DK-2820, Gentofte, Denmark.
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David Owerbach, Jørn Nerup; Restriction Fragment Length Polymorphism of the Insulin Gene in Diabetes Mellitus. Diabetes 1 March 1982; 31 (3): 275–277. https://doi.org/10.2337/diab.31.3.275
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